2 results match your criteria: "Department of Comparative Biomedicine and Food Science of the University of Padova[Affiliation]"
Duration of efficacy and effect of implant location in adult queens treated with a 9.4 mg deslorelin subcutaneous implant.
Theriogenology
January 2025
Department of Animal Medicine, Production and Health of the University of Padova, Italy.
Article Synopsis
- - Deslorelin is a GnRH-agonist used off-label to control reproduction in female cats, and a study evaluated its safety and effectiveness with a 9.4 mg implant placed in either interscapular or periumbilical locations.
- - Over the course of the study, 14 female cats were monitored, showing no significant side effects, with 40% exhibiting signs of estrus post-implantation and an average duration of the implant's effect lasting around 790 days.
- - The treatment led to weight gain in most cats, and importantly, it was reversible as evidenced by some queens being able to mate and conceive after the treatment period ended.
In the mammalian brain, the differentiation of neural cells and the developmental organization of the underlying circuitry are influenced by steroid hormones. The estrogen 17-β estradiol (E2) is one of the most potent regulators of neural growth during prenatal life, synthetized locally from steroid precursors including prenatal testicular testosterone. Estradiol promotes brain differentiation counting sexually dimorphic neural circuits by binding to the estrogen receptors, ER-α and ER-β.
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