7 results match your criteria: "Department of Clinical Research. Electronic address: fujisawa@mie-m.hosp.go.jp.[Affiliation]"
SCCA2 is a reliable biomarker for evaluating pediatric atopic dermatitis.
J Allergy Clin Immunol
May 2018
Division of Medical Biochemistry, Department of Biomolecular Sciences, Saga Medical School, Saga, Japan. Electronic address:
Long-term safety of subcutaneous immunotherapy with TO-204 in Japanese patients with house dust mite-induced allergic rhinitis and allergic bronchial asthma: Multicenter, open label clinical trial.
Allergol Int
July 2018
Department of Clinical Development, Torii Pharmaceutical Co., Ltd., Tokyo, Japan.
Background: To evaluate the long-term safety of subcutaneous immunotherapy with TO-204, a standardized house dust mite (HDM) allergen extracts, we conducted a multicenter, open label clinical trial.
Methods: Japanese patients aged 5-65 years were eligible for the study, if they had HDM-induced allergic rhinitis (AR), allergic bronchial asthma (BA), or both. TO-204 was administered in a dose titration scheme, and the maintenance dose was determined according to the predefined criteria.
Early control treatment with montelukast in preschool children with asthma: A randomized controlled trial.
Allergol Int
January 2018
Allergy Center, Mie National Hospital, Tsu, Japan. Electronic address:
Background: While Japanese guideline recommends initial control treatment for preschool children with asthma symptoms more than once a month, Western guidelines do not. To determine whether control treatment with montelukast was more effective than as-needed β-agonists in this population, we conducted a randomized controlled trial.
Methods: Eligible patients were children aged 1-5 years who had asthma symptoms more than once a month but less than once a week.
"Spike" in acute asthma exacerbations during enterovirus D68 epidemic in Japan: A nation-wide survey.
Allergol Int
January 2018
Institute for Clinical Research, Mie National Hospital, Tsu, Japan. Electronic address:
Article Synopsis
- - In September 2015, Japan saw a significant rise in child asthma hospitalizations linked to an outbreak of enterovirus D68 (EV-D68), prompting an investigation into their relationship.
- - A comprehensive survey spanning nearly six years gathered data from hospitals about asthma-related admissions, finding a marked increase in cases during the EV-D68 epidemic, particularly among children aged 3-6.
- - The study concluded that the surge in asthma hospitalizations was associated with the EV-D68 epidemic, highlighting the importance of monitoring infectious diseases to better manage asthma exacerbations.
Validation and reliability of the Japanese version of the Food Allergy Quality of Life Questionnaire-Parent Form.
Allergol Int
April 2017
Institute for Clinical Research, Mie National Hospital, Mie, Japan. Electronic address:
Background: Food allergy (FA) is a heavy burden for patients and their families and can significantly reduce the quality of life (QoL) of both. To provide adequate support, qualitative and quantitative evaluation of the parents' QoL may be helpful. The objective of this study is to develop and validate a Japanese version of the Food Allergy QoL Questionnaire-Parent Form (FAQLQ-PF-J), an internationally validated disease-specific QoL measurement of the parental burden of having a child with FA.
View Article and Find Full Text PDFSemaphorin 4D is expressed constitutively by human eosinophils.
Allergol Int
September 2015
Institute for Clinical Research, Mie National Hospital, Mie, Japan. Electronic address:
Background: Methylated catechin, one of the active ingredients in green tea, has been reported to ameliorate allergic reactions. We evaluated the efficacy of 'Benifuuki' green tea, which contains O-methylated epigallocatechin-3-O-[3-O-methyl] gallate (O-methylated EGCG), in alleviating Japanese cedar pollinosis (JCP).
Methods: The study was a double-blind, randomized, placebo-controlled trial.