3 results match your criteria: "Department of Clinical Nutrition Medical University of Gdansk[Affiliation]"
DNA methylation profile in patients with indolent systemic mastocytosis.
Clin Transl Allergy
November 2021
Department of Dermatology, Venerology and Allergology Medical University of Gdansk Gdansk Poland.
Article Synopsis
- Mastocytosis is a diverse, often acquired disease of mast cells, primarily driven by a specific mutation (KIT D816V) that influences its severity and treatment approaches.
- This study aimed to examine the connection between symptoms of mastocytosis and epigenetic changes, seeking to find potential epigenetic markers that could predict disease progression.
- Results showed a notable decrease in DNA hydroxymethylation (5-hmC) in patients with indolent systemic mastocytosis compared to healthy individuals, suggesting epigenetic changes are linked to the condition, although other methylation markers were not statistically significant.
Lipoxin (LTX A4 5S, 6R, 15R) levels drastically decrease after 5 years of hemodialysis treatment.
J Physiol Pharmacol
June 2020
Department of Clinical Nutrition Medical University of Gdansk, Gdansk, Poland.
The increased risk of atherosclerosis in patients with chronic kidney disease (CKD) is associated with the increased concentration of fatty acids from the omega-6 family. Products of arachidonic acid oxidation, including prostaglandins, thromboxanes, hydroxyleicosa-tetraenoic acids (HETES) and hydroxyoctadecadienoic acids (HODES) are involved in the pathogenesis of cancer and cardiovascular diseases due to increased oxidative stress. The aim of our study was to determine the relations resulting from the duration of CKD treatment.
View Article and Find Full Text PDFFatty acid (FA) profiles in the plasma of patients with metabolic syndrome and chronic kidney disease (CKD) seem to be identical despite their different etiology (dietary mistakes vs. cachexia). The aim of this study was to compare both profiles and to highlight the differences that could influence the improvement of the treatment of patients in both groups.
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