4,629 results match your criteria: "Department of Clinical Epidemiology and Biostatistics[Affiliation]"
Factors in Parenting Stress in Young Patients With Breast Cancer and Implications for Children's Emotional Development: The PSYCHE Study.
JAMA Netw Open
November 2023
Department of Surgery, University of Ulsan College of Medicine, Asan Medical Center, Seoul, South Korea.
Article Synopsis
- A study was conducted in Seoul, South Korea, involving mothers with stage 0 to 3 breast cancer to understand the impact of the disease on their parenting stress and their children's emotional development.
- It was found that mothers with children experienced higher rates of depression, especially those undergoing specific treatments, while the duration of their illness was linked to lower depression levels.
- The results highlighted factors such as caring for older children and being the primary caregiver that influenced parenting stress, indicating that these women face significant emotional challenges alongside their health issues.
Differential Diagnosis of Thickened Gastric Wall between Hypertrophic Gastritis and Borrmann Type 4 Advanced Gastric Cancer.
Gut Liver
November 2024
Department of Gastroenterology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.
Background/aims: : Accurately diagnosing diffuse gastric wall thickening is challenging. Hypertrophic gastritis (HG), while benign, mimics the morphology of Borrmann type 4 advanced gastric cancer (AGC B-4). We compared the features of endoscopy and endoscopic ultrasonography (EUS) between them.
View Article and Find Full Text PDFArticle Synopsis
- - The study focused on the effects of mammographic breast density reduction (MDR) on treatment outcomes in premenopausal women with estrogen receptor-positive breast cancer who received either tamoxifen alone or in combination with ovarian function suppression (OFS).
- - Results from the ASTRRA trial showed that while the rate of MDR positivity was similar in both treatment groups, patients receiving tamoxifen plus OFS who were MDR-positive experienced significantly better disease-free survival compared to those who were MDR-negative.
- - The findings highlight the potential importance of MDR as a positive prognostic factor specifically in patients treated with tamoxifen and OFS, suggesting a need for tailored treatment approaches based on MDR status.
Co-Designing a Strategy for Implementing the SPARC Holistic Needs Assessment Tool in the Colombian Clinical Context.
Healthcare (Basel)
November 2023
Medical Biology Centre, School of Nursing and Midwifery, Queen's University Belfast, Belfast BT9 7BL, UK.
In Colombia, timely access to palliative care (PC) is hampered by difficulties in identifying and referring to necessary services. The SPARC (Sheffield Profile for Assessment and Referral for Care) instrument provides a holistic needs assessment to improve referrals for different forms of care. SPARC was recently validated in Colombian Spanish (SPARC-Sp) but has not yet been implemented in clinical practice.
View Article and Find Full Text PDFArticle Synopsis
- Kidney transplantation is the best treatment for patients with serious kidney disease because it leads to better health compared to staying on dialysis.
- Many people who get kidney transplants still face problems like rejection and failure of the new kidney, and doctors want to find better ways to check kidney health without doing invasive tests.
- A review of past research looked at different proteins in patients' samples to find potential new markers that could help predict kidney problems after a transplant.
Author Correction: Association between weight loss agents and elevated liver enzymes: a population‑based cross‑sectional study.
Sci Rep
November 2023
College of Pharmacy, Chungnam National University, Daejeon, Republic of Korea.
The estimated effect of increasing fruit interventions on controlling body weight in children and adolescents: A meta-analysis.
Prev Med
February 2024
Department of Clinical Epidemiology and Biostatistics, Children's Hospital of Chongqing Medical University, National Clinical Research Center for Child Health and Disorders, Ministry of Education Key Laboratory of Child Development and Disorders, Chongqing Key Laboratory of Pediatrics, Chongqing 400016, China. Electronic address:
Background: The impact of increased fruit consumption on weight change remains a matter of debate.
Objective: This study aimed to evaluate the effects of interventions targeted at promoting fruit consumption and managing body weight in children and adolescents.
Methods: Four electronic databases, including PubMed, Web of science, Embase, and the Cochrane Library, were searched from January 1, 2000, to October 10th, 2023, to identify Randomized controlled trials (RCTs) that assessed changes in fruit consumption and obesity indicators.
Multidisciplinary Shared Decision Making for Fertility Preservation in Young Women With Breast Cancer.
J Breast Cancer
December 2023
Division of Breast Surgery, Department of Surgery, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.
Purpose: Fertility preservation (FP) is an important issue for young survivors of breast cancer. Although international guidelines recommend pre-treatment fertility counseling for women with breast cancer, there is no standardized protocol or referral system for FP in South Korea. There are also barriers to discussing FP that make patient-centered decision making difficult.
View Article and Find Full Text PDFFeasibility and outcomes of using DIALOG+ in primary care to improve quality of life and mental distress of patients with long-term physical conditions: an exploratory non-controlled study in Bosnia and Herzegovina, Colombia and Uganda.
BMC Prim Care
November 2023
Unit for Social and Community Psychiatry, East London NHS Foundation Trust, London, UK.
Introduction: The management of long-term physical conditions is a challenge worldwide, absorbing a majority resources despite the importance of acute care. The management of these conditions is done largely in primary care and so interventions to improve primary care could have an enormous impact. However, very little data exist on how to do this.
View Article and Find Full Text PDFCOPD Risk Factor Profiles in General Population and Referred Patients: Potential Etiotypes.
Int J Chron Obstruct Pulmon Dis
November 2023
Department of Pulmonary and Critical Care Medicine, Asan Medical Centre, University of Ulsan College of Medicine, Seoul, Republic of Korea.
Article Synopsis
- The study aimed to identify the risk factors for chronic obstructive pulmonary disease (COPD) in both a general population and referred COPD patients, utilizing data from two distinct datasets.
- Findings showed that the mean age of COPD patients was 67 years, with notable differences in gender distribution and forced expiratory volume between participants from the general population and referral clinics.
- Key risk factors identified included cigarette smoking, infections, pollution, and asthma, with significant variations in prevalence between the datasets, highlighting a need to investigate unidentified risk factors in the general population.
Factors associated with patency of self-expandable metal stents in malignant biliary obstruction.
BMC Gastroenterol
November 2023
Department of Clinical Epidemiology and Biostatistics, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.
Introduction: Endoscopic self-expandable metal stent (SEMS) placement is the key endoscopic treatment for unresectable malignant biliary obstruction. The benefit of covered SEMS over uncovered SEMS remains unknown as are risk factors for SEMS dysfunction. This study aimed to determine the factors associated with patency of SEMS.
View Article and Find Full Text PDFRETRACTED: Choi et al. Validation of the CHA2DS2-VA Score (Excluding Female Sex) in Nonvalvular Atrial Fibrillation Patients: A Nationwide Population-Based Study. 2022, , 1823.
J Clin Med
October 2023
Asan Medical Center, Department of Clinical Epidemiology and Biostatistics, University of Ulsan College of Medicine, Seoul 05505, Republic of Korea.
The journal retracts the article "Validation of the CHA2DS2-VA Score (Excluding Female Sex) in Nonvalvular Atrial Fibrillation Patients: A Nationwide Population-Based Study" [...
View Article and Find Full Text PDFMechanical ventilation practices in Asian intensive care units: A multicenter cross-sectional study.
J Crit Care
February 2024
Department of Pulmonary and Critical Care Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, South Korea. Electronic address:
Article Synopsis
- The study examined current mechanical ventilation practices in Asian intensive care units, specifically focusing on tidal volume, plateau pressure, and PEEP in patients.
- Data from 1408 patients were analyzed, highlighting that while low tidal volume was utilized in patients with ARDS, a large proportion of those without ARDS received intermediate tidal volumes, with adequate plateau pressure noted in most cases.
- The research found that factors like income classification, patient age, severity of illness, and certain clinical measures significantly influenced mortality rates, which escalated with higher predictive scores for mortality.
Cost-effectiveness analysis of isolation strategies for asymptomatic and mild symptom COVID-19 patients.
Cost Eff Resour Alloc
November 2023
Faculty of Medicine Ramathibodi Hospital, Chakri Naruebodindra Medical Institute, Mahidol University, Samut Prakan, Thailand.
Background: Management of COVID-19 patients with mild and moderate symptoms could be isolated at home isolation (HI), community isolation (CI) or hospitel. However, it was still unclear which strategy was more cost-effective. Therefore, this study was conducted to evaluate this.
View Article and Find Full Text PDFResults From a Virtual Clinic for the Follow-up of Patients Using the Advanced Hybrid Closed-Loop System.
J Diabetes Sci Technol
November 2023
Department of Clinical Epidemiology and Biostatistics, Pontificia Universidad Javeriana, Bogotá, Colombia.
Background: Evidence regarding the implementation of medium-term strategies in advanced hybrid closed-loop (AHCL) system users is limited. Therefore, this study aimed to describe the efficacy and safety of the AHCL system in patients with type 1 diabetes (T1D) on a six-month follow-up in a virtual diabetes clinic (VDC).
Method: A prospective cohort of adult patients with T1D treated using the AHCL system (Mini Med 780G; Medtronic, Northridge, California) in a VDC follow-up.
Door-to-device time and mortality in patients with ST-elevation myocardial infarction treated with primary percutaneous coronary intervention: insight from real world data of Thai PCI Registry.
Cardiovasc Diagn Ther
October 2023
Cardiology Unit, Department of Medicine, Phramongkutklao Hospital, Bangkok, Thailand.
Background: Timely reperfusion therapy is recommended for patients with ST-segment elevation myocardial infarction (STEMI), and system delay <90 minutes and door-to-device (D2D) time <60 minutes are recommended by the 2017 ESC Guidelines for the management of STEMI patients and have been proposed as a performance measure for triaging patients for primary percutaneous coronary intervention (PCI). However, previous research produced contradictory results regarding the association between D2D time and mortality. Therefore, this study aimed to examine the associations between D2D time and mortality in Thailand.
View Article and Find Full Text PDFComparative cardiovascular outcomes of novel drugs as an addition to conventional triple therapy for heart failure with reduced ejection fraction (HFrEF): a network meta-analysis of randomised controlled trials.
Open Heart
November 2023
Department of Clinical Epidemiology and Biostatistics, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.
Background: Currently, there is no head-to-head comparison of novel pharmacological treatments for heart failure with reduced ejection fraction (HFrEF). A network meta-analysis aimed to compare effects of both conventional and alternative drug combinations on time to develop primary composite outcome of cardiovascular death or heart failure hospitalisation (PCO).
Methods: Randomised controlled trials (RCTs) were identified from Medline, Scopus up to June 2021.
Risk of malignancies and chemopreventive effect of statin, metformin, and aspirin in Korean patients with ulcerative colitis: a nationwide population-based study.
Intest Res
November 2023
Department of Gastroenterology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.
Background/aims: We investigated the incidences of overall and site-specific malignancies and chemopreventive effects of statin, metformin, and aspirin in patients with ulcerative colitis.
Methods: We collected data using the Health Insurance Review and Assessment claims database from January 2007 to April 2020.
Results: The overall malignancy risk among the 35,189 ulcerative colitis patients was similar to that of the general population (standardized incidence ratio, 0.
Author Correction: Risk of incident autoimmune diseases in patients with newly diagnosed psoriatic disease: a nationwide population-based study.
Sci Rep
November 2023
Department of Dermatology, Asan Medical Center, University of Ulsan College of Medicine, 88, Olympic-ro 43-gil, Songpa-gu, Seoul, 05505, Korea.
Association Between Body Weight Changes and Subsequent Development of Out-of-Hospital Cardiac Arrest: A Population-Based Nested Case-Control Study.
J Korean Med Sci
November 2023
Department of Emergency Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.
Background: Body weight is a modifiable demographic factor. Although the association of body mass index (BMI) categories with sudden cardiac death was reported, dynamic changes of BMI and the risk of cardiac arrest remain unknown. This study aimed to evaluate the association between the out-of-hospital cardiac arrest (OHCA) occurrence within a year and the percent changes of BMI preceding the OHCA.
View Article and Find Full Text PDFImpact of Patient Sex on Adverse Events and Unscheduled Utilization of Medical Services in Cancer Patients Undergoing Adjuvant Chemotherapy: A Multicenter Retrospective Cohort Study.
Cancer Res Treat
April 2024
Division of Hematology and Medical Oncology, Department of Internal Medicine, Seoul National University Bundang Hospital, Seoul National University College of Medicine, Seongnam, Korea.
Article Synopsis
- The study investigates sex differences in adverse events (AEs) from chemotherapy, focusing on how these differences affect healthcare use and treatment outcomes in female patients.
- Results show that women experienced more frequent and severe AEs like nausea and neutropenia, leading to lower chemotherapy dose intensity and more dose reductions than men.
- The findings highlight the need for physicians to consider gender-specific responses to chemotherapy when making treatment decisions.
Bovine pericardial versus porcine bioprosthetic aortic valves: A nationwide population-based cohort study in Korea.
J Thorac Cardiovasc Surg
November 2024
Department of Cardiology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea. Electronic address:
Objective: To compare the clinical outcomes of aortic valve replacement (AVR) using bovine pericardial and porcine bioprostheses, utilizing a nationwide administrative claims database.
Methods: Adult patients (age ≥40 years) who underwent bioprosthetic AVR, without other valve replacements, between 2003 and 2018 were identified from the Korean National Health Insurance Service database. The outcomes of interest were all-cause mortality, cardiac mortality, and valve-related events, including the incidence of reoperation, endocarditis, systemic thromboembolism, and major bleeding.
Delayed versus primary closure to minimize risk of surgical-site infection for complicated appendicitis: A secondary analysis of a randomized trial using counterfactual prediction modeling.
Infect Control Hosp Epidemiol
March 2024
Department of Clinical Epidemiology and Biostatistics, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.
Article Synopsis
- - This study evaluates the risk of surgical site infections (SSI) in patients who had complicated appendectomies, comparing two closure methods: delayed primary closure (DPC) and primary closure (PC) while considering individual risk factors.
- - Conducted as a secondary analysis of a randomized controlled trial involving 546 adult patients, the research applied a prediction model that incorporated various predictors such as diabetes and fecal contamination.
- - Results indicated that about 38.1% of patients had a lower SSI risk with PC compared to DPC, particularly those with diabetes and ruptured appendicitis, suggesting early PC may be more beneficial in reducing SSI for patients with complicated appendicitis.
Sanya climatic-treatment cohort profile: objectives, design, and baseline characteristics.
Front Public Health
November 2023
Department of Science and Education, Hainan Branch, Shanghai Children's Medical Center, School of Medicine, Shanghai Jiao Tong University, Sanya, China.
Article Synopsis
- The study investigates the effects of tropical climates on allergic diseases among elderly individuals who migrate from northern China to Sanya City, Hainan Province, for the winter.
- A total of 756 participants, averaging 66.1 years old, were assessed for various allergic conditions, with results indicating significant symptom relief while living in the tropical environment.
- Preliminary findings suggest that the warmer climate may improve conditions such as allergic rhinitis, asthma, and COPD in these migratory-bird old people.
Years of life lost and long-term outcomes due to glomerular disease in a Southeast Asian Cohort.
Sci Rep
November 2023
Department of Medicine Faculty of Medicine Ramathibodi Hospital, Mahidol University, Rama 6 Road, Bangkok, 10400, Thailand.
Death and end-stage kidney disease (ESKD) are major outcomes of glomerular disease. (GD) The years of potential life lost (YLL) may provide additional insight into the disease burden beyond death rates. There is limited data on premature mortality in GD.
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