5 results match your criteria: "Department of Clinical Chemistry (KCHL)[Affiliation]"
Unsafe testosterone-based dosing regimen of androgen deprivation therapy in patients with locally advanced or metastatic prostate cancer: a prematurely ended randomized controlled trial (MIDAS-trial).
Acta Oncol
April 2021
Department of Oncology, Franciscus Gasthuis & Vlietland, Rotterdam, The Netherlands.
Evaluation of new laboratory tests to discriminate bacterial from nonbacterial chronic obstructive pulmonary disease exacerbations.
Int J Lab Hematol
December 2016
Department of Clinical Chemistry (KCHL), Franciscus Gasthuis, Rotterdam, The Netherlands.
Introductions: Discriminating bacterial from nonbacterial acute exacerbations of chronic obstructive pulmonary disease (AECOPD) is difficult, causing antibiotics overuse and bacterial resistance. Sputum cultures are of limited use because results take time. In our hospital, only leukocyte concentration and CRP are laboratory parameters evaluated in AECOPD.
View Article and Find Full Text PDFA new flow cytometric method for differential cell counting in ascitic fluid.
Cytometry B Clin Cytom
November 2016
Department of Clinical Chemistry (KCHL), Sint Franciscus Gasthuis, 3045 PM, Rotterdam, The Netherlands.
Background: Cell counts in bodyfluids such as ascitic fluid can be difficult to perform and report rapidly. The current gold standard for cell counting in body fluids is a suitable automated cell counter or a manual counting chamber, combined with differential counting on a cytospin. This technique has several disadvantages, so we designed a new flow cytometric test for cell counting in ascites.
View Article and Find Full Text PDFA new flow cytometric method for differential cell counting in ascitic fluid.
Cytometry B Clin Cytom
February 2014
Department of Clinical Chemistry (KCHL), Sint Franciscus Gasthuis, Kleiweg 500, 3045 PM, Rotterdam, The Netherlands.
Background: Cell counts in bodyfluids such as ascitic fluid can be difficult to perform and report rapidly. The current gold standard for cell counting in body fluids is a suitable automated cell counter or a manual counting chamber, combined with differential counting on a cytospin. This technique has several disadvantages, so we designed a new flow cytometric test for cell counting in ascites.
View Article and Find Full Text PDFLeukoflow: multiparameter extended white blood cell differentiation for routine analysis by flow cytometry.
Cytometry A
September 2011
Department of Clinical Chemistry (KCHL), Sint Franciscus Gasthuis, Kleiweg, PM Rotterdam, The Netherlands.
Article Synopsis
- Differential white blood cell count (dWBC) is used to diagnose conditions by analyzing blood samples, typically performed through automated counters and occasionally requiring manual microscopy for accuracy.
- Microscopy is labor-intensive and can lead to discrepancies due to observer variations, while flow cytometry provides a more efficient and comprehensive alternative with the ability to count more cells and identify different leukocyte types.
- The newly developed assay, called Leukoflow, utilizes a specific antibody cocktail for rapid and precise identification of multiple blood cell populations, showing good correlation with automated counts and less variation in blast counts compared to traditional methods.