5 results match your criteria: "Department of Chemistry Columbia University New York[Affiliation]"
In Vivo Protein-Protein Interaction Assays: Beyond Proteins We would like to thank Tony Siu, Dr. Charles Cho, and the members of our lab for their helpful comments as we were preparing this manuscript.
Angew Chem Int Ed Engl
March 2001
Department of Chemistry Columbia University New York, NY 10027 (USA).
In Vivo Protein-Protein Interaction Assays: Beyond Proteins.
Angew Chem Int Ed Engl
March 2001
Department of Chemistry Columbia University New York, NY 10027 (USA) Fax: (+1) 212-932-1289.
The scope of cell-based assays is being expanded to allow the detection of interactions between proteins and DNA, RNA, or small molecules. The yeast two-hybrid assay, which normally detects protein-protein interactions, can be modified to detect interactions between ligands (the two dark yellow shapes in the diagram) and receptors (DHFR or GR). A small bridging molecule (made up of the ligands joined together) is used to join two fusion proteins (DHFR-DBD and AD-GR), thereby activating the reporter gene.
View Article and Find Full Text PDFSelective Hydroxylation of a Steroid at C-9 by an Artificial Cytochrome P-450 We thank the National Institutes of Health, the National Science Foundation, and the Environmental Protection Agency for financial support of this research. J.Y. acknowledges support from an NCERQA EPA Graduate Fellowship and a Bristol-Myers Squibb Graduate Fellowship.
Angew Chem Int Ed Engl
August 2000
Department of Chemistry Columbia University New York, NY 10027 (USA).
Highly Regioselective Oxygenation of C-H Bonds: Diamidomanganese Constructs with Attached Substrates as Catalyst Models Financial support has been provided by Columbia University and the Camille and Henry Dreyfus Foundation. P.M.W. acknowledges the REU-NSF program for summer support. We also thank Dr. J. B. Schwarz (manuscript preparation) and Dr. Y. Itagaki (mass spectrometry).
Angew Chem Int Ed Engl
May 2000
Department of Chemistry Columbia University New York, NY 10027 (USA).