The study aimed to evaluate how the medication sacubitril/valsartan affects right ventricular (RV) function in patients with pulmonary hypertension (PH) caused by heart failure with reduced ejection fraction (HFrEF).
A total of patients with HFrEF-induced PH were given either sacubitril/valsartan or enalapril for 6 months, with assessments through echocardiography conducted at the start and after treatment.
Results showed that sacubitril/valsartan significantly improved key heart function metrics compared to enalapril, indicating it has more beneficial effects on RV function and reduces pulmonary pressure in these patients.