4 results match your criteria: "Department of Cardiology Chinese PLA General Hospital Beijing China.[Affiliation]"
Article Synopsis
- The study explored how a high-fat diet (HFD) leads to obesity and its potential link to the coexistence of cardiovascular disease and cancer in ApoE knockout mice.
- Mice on a HFD developed larger tumors and more atherosclerosis compared to those on a normal diet, indicating a connection between obesity and the severity of both diseases.
- Changes in specific biomarkers, like LOX-1 and vascular endothelial growth factor, were observed in the HFD group, suggesting that these might contribute to the progression of cancer and cardiovascular issues simultaneously.
Article Synopsis
- A clinical trial named CHANGE examined how nicorandil, a drug that may enhance blood flow and reduce heart damage, affects infarct size in heart attack patients undergoing a procedure called primary percutaneous coronary intervention.
- The study included 238 patients who were randomly assigned to receive either nicorandil or a placebo prior to their treatment, with a focus on measuring infarct size using cardiac magnetic resonance imaging at 5 to 7 days and 6 months later.
- Results showed that the nicorandil group had significantly smaller infarct sizes, less incidence of complications during the procedure, and better overall heart function compared to the placebo group.
The emergence of coronavirus disease 2019 (COVID-19), caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has become a major global public health concern. Although SARS-CoV-2 causes primarily respiratory problems, concurrent cardiac injury cannot be ignored since it may be an independent predictor for adverse outcomes. Cardiac arrhythmias are often observed in patients with COVID-19, especially in severe cases, and more likely contribute to the high risk of adverse outcomes.
View Article and Find Full Text PDFBackground Neutrophils play a major role in inflammation after myocardial ischemia-reperfusion (I/R) injury. The effects of mesenchymal stem cells (MSCs) on neutrophils in I/R are complex and not fully understood. This study was designed to investigate the effects and mechanism of MSCs on alleviating myocardial I/R injury in rats.
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