2 results match your criteria: "Department of Cardiology Ankara City Hospital Ankara Turkey.[Affiliation]"
Association Between Claims-Defined Frailty and Outcomes Following 30 Versus 12 Months of Dual Antiplatelet Therapy After Percutaneous Coronary Intervention: Findings From the EXTEND-DAPT Study.
J Am Heart Assoc
July 2023
Richard A. and Susan F. Smith Center for Outcomes Research in Cardiology, Division of Cardiovascular Medicine Beth Israel Deaconess Medical Center Boston MA USA.
Article Synopsis
- This study examined the impact of frailty on outcomes in older patients (≥65 years) undergoing dual antiplatelet therapy (DAPT) after percutaneous coronary intervention, using Medicare claims data to define frailty.
- Results showed that frail patients had a significantly higher rate of adverse clinical events (23.1%) compared to nonfrail patients (10.7%) at 18 months follow-up.
- While there were no notable differences in the effects of standard versus extended duration DAPT on outcomes for frail versus nonfrail patients, further research is needed to explore how frailty affects bleeding and ischemic risks with DAPT.
Background: The prolongation of repolarization time between the myocardial epicardium and endocardial cells is closely related to malignant ventricular arrhythmias. The purpose of our study was to compare repolarization markers, namely, T-wave peak-end interval (Tp-e), QT, corrected QT (QTc), Tp-e/QT, Tp-e/corrected QT (QTc), and Heart Rate Variability (HRV) values in healthy men and women and to investigate their daily variations.
Methods: A total of 74 male and 78 female participants, being a government employee, and having no health problems, were included in the two study groups (males and females).