1 results match your criteria: "Department of Biochemistry Hamamatsu University School of Medicine 1-20-1 Handayama[Affiliation]"
variants in and cause neurodevelopmental disorders.
Ann Clin Transl Neurol
March 2018
Department of Biochemistry Hamamatsu University School of Medicine 1-20-1 Handayama, Higashi-ku Hamamatsu 431-3192 Japan.
Objective: () and () isoforms of Calcium/calmodulin-dependent protein kinase II (CaMKII) play a pivotal role in neuronal plasticity and in learning and memory processes in the brain. Here, we explore the possible involvement of - and -CaMKII variants in neurodevelopmental disorders.
Methods: Whole-exome sequencing was performed for 976 individuals with intellectual disability, developmental delay, and epilepsy.