Development of the Pipette-Tip Micro-Solid-Phase Extraction for Extraction of Rutin From Lam. Using Activated Hollow Carbon Nanospheres as Sorbents.

Herein, a micro-solid-phase extraction (SPE) method was developed using a pipette tip for rutin extraction, employing activated hollow carbon nanospheres (HCNSs) as the sorbent. Characterization of the activated carbon nanospheres through TGA, FTIR, and SEM analysis confirmed the success of the activation process. The study demonstrated the efficacy of PT-SPE in rutin extraction under pH 2 conditions with a standard concentration of 2 mg·L.