Chemical profiling, toxicity assessment, anti-diarrhoeal, anti-inflammatory and antinociceptive activities of Canarium schweinfurthii Engl. (Burseraceae) bark in rats.

Ethnopharmacological Relevance: The bark of Canarium schweinfurthii is used in ethnomedicine for the treatment of diabetes, pain, malaria, fever and diarrhoea.

Aim Of The Study: The chemical phytoconstituents, antidiarrheal, anti-inflammatory and antinociceptive effects and safety profile of the aqueous extract of Canarium schweinfurthii bark (AECSB) were investigated.

Materials And Methods: Gas chromatography-mass spectrometry (GC-MS) was used to analyse the phytochemical composition.

Phytochemical profiling, toxicity studies, wound healing, analgesic and anti-inflammatory activities of Musa paradisiaca L. Musaceae (Plantain) stem extract in rats.

Ethnopharmacological Relevance: The stem of Musa paradisiaca (plantain) has found application in traditional medicine for the treatment of diabetes, inflammation, ulcers and wound injuries.

Aim Of The Study: This study investigated the phytochemical composition, toxicity profile, wound healing, anti-inflammatory and analgesic effects of aqueous Musa paradisiaca stem extract (AMPSE) in rats.

Methods: Phytochemical analysis of methanol-MPSE was performed by gas chromatography-mass spectrometry (GC-MS).

Evaluating bioactive constituents and toxicological effects of aqueous extract of fermented seeds in rats.

Objective: This study aimed at evaluating the bioactive constituents and the toxicological profile of the aqueous fermented seed extract of .

Materials And Methods: The chemical constituents of fermented were assessed using GC-MS. For acute toxicity study, one-time doses of up to 5000 mg/kg of the extract were orally administered to male and female rats whereas 200, 400 and 800 mg/kg of the extract were orally administered daily for 14 days in sub-acute toxicity investigation.

Toxicological profile of the aqueous-fermented extract of in rats.

Objective: This study was conducted to assess the toxicity profile of the aqueous-fermented extract of in rats.

Materials And Methods: In acute toxicity test, the rats of different groups were orally administered with a single dose of 500, 1000, 2000 and 5000 mg/kg of fermented extract of . The rats were monitored for behavioral changes, toxicity signs and mortality.