6 results match your criteria: "Department of Applied and Computational Mathematics and Statistics University of Notre Dame[Affiliation]"
Ambient air pollution is an increasing threat to society, with rising numbers of adverse outcomes and exposure inequalities worldwide. Reducing uncertainty in health outcomes models and exposure disparity studies is therefore essential to develop policies effective in protecting the most affected places and populations. This study uses the concept of information entropy to study tradeoffs in mortality uncertainty reduction from increasing input data of air pollution versus health outcomes.
View Article and Find Full Text PDFConducting ecological research in a way that addresses complex, real-world problems requires a diverse, interdisciplinary and quantitatively trained ecology and environmental science workforce. This begins with equitably training students in ecology, interdisciplinary science, and quantitative skills at the undergraduate level. Understanding the current undergraduate curriculum landscape in ecology and environmental sciences allows for targeted interventions to improve equitable educational opportunities.
View Article and Find Full Text PDFJ Comput Biol
May 2022
Department of Statistics, Rice University, Houston, Texas, USA.
Introduction: It is unknown how the brain coordinates decisions to withstand personal costs in order to prevent other individuals' distress. Here we test whether local field potential (LFP) oscillations between brain regions create "neural contexts" that select specific brain functions and encode the outcomes of these types of intersubjective decisions.
Methods: Rats participated in an "Intersubjective Avoidance Test" (IAT) that tested rats' willingness to enter an innately aversive chamber to prevent another rat from getting shocked.
J R Soc Interface
May 2015
Department of Applied and Computational Mathematics and Statistics University of Notre Dame, Notre Dame, IN 46556, USA
A novel biofilm model is described which systemically couples bacteria, extracellular polymeric substances (EPS) and solvent phases in biofilm. This enables the study of contributions of rheology of individual phases to deformation of biofilm in response to fluid flow as well as interactions between different phases. The model, which is based on first and second laws of thermodynamics, is derived using an energetic variational approach and phase-field method.
View Article and Find Full Text PDFAnn Appl Stat
January 2014
Center for Statistical Genetics Pennsylvania State University Hershey, Pennsylvania 17033 USA
With the recent advent of high-throughput genotyping techniques, genetic data for genome-wide association studies (GWAS) have become increasingly available, which entails the development of efficient and effective statistical approaches. Although many such approaches have been developed and used to identify single-nucleotide polymorphisms (SNPs) that are associated with complex traits or diseases, few are able to detect gene-gene interactions among different SNPs. Genetic interactions, also known as epistasis, have been recognized to play a pivotal role in contributing to the genetic variation of phenotypic traits.
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