2 results match your criteria: "Department of Anesthesiology and Regional Burn Center[Affiliation]"

Plasma, urine and skin pharmacokinetics of cefepime in burns patients.

J Antimicrob Chemother

August 2000

Laboratory of Pharmacokinetics, Hôpital de la Timone and Université de la Méditerranée, and Department of Anesthesiology and Regional Burn Center, Hôpital de la Conception, Marseille, France.

We studied the pharmacokinetics of cefepime (2 g bd) in six burns patients. Blood, urine and skin samples were collected to measure cefepime concentrations. A two-compartment model was fitted to the data.

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Plasma levels of visceral proteins (VP) are commonly used for evaluation of nutritional status. Low values observed in burn patients are caused by several factors including microvascular hyper-permeability and inflammatory processes. The aim of the study was to define a range of standard values specific to burn patients.

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