1 results match your criteria: "Departamento de Estudios Básicos Integrados. Grupo Estudios BioSociales Del Cuerpo. School of Dentistry[Affiliation]"
Oral lichen planus: A chronic inflammatory model to study the regulation of the Toll-like receptor signaling in oral keratinocytes.
J Oral Biosci
June 2020
Departamento de Estudios Básicos Integrados. Grupo Estudios BioSociales Del Cuerpo. School of Dentistry, Universidad de Antioquia, Medellin, Antioquia, Colombia. Electronic address:
Article Synopsis
- Oral lichen planus (OLP) is a chronic inflammatory disease linked to immune responses and potential malignant transformation, though its exact causes are still unclear.
- The review focuses on the role of Toll-like receptors (TLRs) in OLP, highlighting how TLR activation affects oral keratinocyte behavior, with a particular emphasis on the Interferon Regulatory Factor (IRF) family, especially IRF6.
- A hypothetical model suggests that TLR2 activation could regulate the inflammatory processes in OLP, emphasizing the need for further research on the molecular interactions involving oral keratinocytes.