5,025 results match your criteria: "Dental Research Institute.[Affiliation]"

Background: The Depression, Anxiety, Stress Scales-21 (DASS-21) contain three subscales measuring depression, anxiety, and stress. Several abbreviated DASS-21 versions have been developed, demonstrating better clinical utility and measurement properties than the original instrument. This study explored the factor structure of various abbreviated DASS-21 versions and identified/validated the optimal one for assessing young adults with temporomandibular disorders (TMDs).

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Next-generation sequencing analysis of bacterial species present in the sequestrum of medication-related osteonecrosis of the jaw patients.

Arch Oral Biol

January 2025

Department of Oral and Maxillofacial Surgery, Pusan National University, Yangsan, South Korea; Dental and Life Science Institute, School of Dentistry, Pusan National University, Yangsan, South Korea; Dental Research Institute, Pusan National University Dental Hospital, Yangsan, South Korea. Electronic address:

Objective: Antiresorptives cases of adverse reactions to highly effective drugs used to treat skeletal-related events that occur during treatment of osteoporosis or malignancy have been reported in the jaw. To date, there is no clear pathophysiology for medication-related osteonecrosis of the jaw (MRONJ), but the role of inflammation or infection has been proposed as one of several possible pathogenesis theories. This study was designed to investigate the role of infection in the pathogenesis of MRONJ by analyzing the microbial communities observed in the bone samples from MRONJ patients.

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Effect of EGCG-Methacrylate-Functionalized Resin Infiltrant on White Spot Lesions: An In Vitro Study.

J Funct Biomater

December 2024

Department of Operative Dentistry, School of Dentistry, University of São Paulo, Avenida Professor Lineu Prestes, 2227, São Paulo 05508-000, SP, Brazil.

This study evaluated the color change (ΔE) and penetration depth (PD) of white spot lesions (WSLs) infiltrated with the resin infiltrant (Icon) functionalized with methacrylate epigallocatechin-3-gallate (EGCG). To introduce polymerizable double bonds, EGCG was reacted with methacryloyl chloride (EM). Subsequently, the Icon resin infiltrant (I) was loaded with neat EGCG (IE) or EGCG-methacrylate (IEM) at 2 wt% each.

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Clinical outcome and volumetric 3D analysis of biofluorescence imaging system guided surgery for Medication-Related Osteonecrosis of the Jaw(MRONJ).

BMC Oral Health

January 2025

Department of Oral and Maxillofacial Surgery, Section of Dentistry, Seoul National University Bundang Hospital, 82 Gumi-ro 173 beon-gil, Bundang-gu, Bundang‑gu, 13620, Seongnam, Republic of Korea.

Background: This study aims to evaluate the clinical outcome of biofluorescent imaging system (BIS) guided MRONJ surgery through analyzing 3D volumetric changes in CBCT data of bone structure.

Methods: BIS-guided surgery for MRONJ surgery was performed by grinding red-fluorescent area from remained residual bone detected by Qray-pen. CBCT data was collected preoperatively, postoperatively, and at last follow-up more than 3 months of each patient.

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Fracture resistances of heat-treated nickel-titanium files used for minimally invasive instrumentation.

BMC Oral Health

January 2025

Department of Conservative Dentistry, School of Dentistry, Dental Research Institute, Dental and Life Science Institute, Pusan National University, Yangsan, Korea.

Background: This study compared the torsional resistance, bending stiffness, and cyclic fatigue resistances of different heat-treated NiTi files for minimally invasive instrumentation.

Methods: TruNatomy (TN) and EndoRoad (ER) file systems were compared with ProTaper Gold (PG). Torsional load, distortion angle, and bending stiffness were assessed using a custom device AEndoS, and toughness was calculated using the torsional data.

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Background: The utilization of dental care is affected by different factors. Despite the importance of dental care, there are significant disparities in its utilization among various population groups. The aim of this study was to identify the main factors of dental care utilization and the influences of the Health Transformation Plan (HTP) in Iran based on the Anderson model.

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Classification and prognostic evaluation of ameloblastoma using multiplanar CT imaging: a retrospective analysis.

BMC Oral Health

January 2025

Department of Oral and Maxillofacial Radiology and Dental Research Institute, School of Dentistry, Seoul National University, Seoul, Republic of Korea.

Background: Ameloblastoma is the most prevalent odontogenic tumor of the jaw, with a significant recurrence rate. It was conventionally classified radiographically as unilocular or multilocular. As 3D images become more common, there is a need to reassess this classification.

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Objectives: Besides physical health risks, large public health events also exert negative impacts on people's mental health. We aimed to explore the prevalence and correlates of mental distress and its association with psychological resilience among countries amid the Omicron wave.

Methods: We conducted cross-sectional surveys simultaneously in China and South Korea from March 15 to 30, 2023.

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Objectives: This study aimed to develop an automated method for generating clearer, well-aligned panoramic views by creating an optimized three-dimensional (3D) reconstruction zone centered on the teeth. The approach focused on achieving high contrast and clarity in key dental features, including tooth roots, morphology, and periapical lesions, by applying a 3D U-Net deep learning model to generate an arch surface and align the panoramic view.

Methods: This retrospective study analyzed anonymized cone-beam CT (CBCT) scans from 312 patients (mean age 40 years; range 10-78; 41.

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Validity of quantitative values of quantitative light-induced fluorescent (QLF) device for pulp diagnosis of teeth with cracks.

J Dent

January 2025

Department of Conservative Dentistry, Dental and Life Science Institute, School of Dentistry, Pusan National University, Dental Research Institute, Yangsan, Republic of Korea. Electronic address:

Introduction: The Quantitative Light-Induced Fluorescence (QLF) device provides both the visual information of crack lines on tooth surfaces and quantitative values for fluorescence reactions. The aim of this study was to evaluate the correlation and assess the usefulness of QLF quantitative values in pulp diagnosis of teeth with cracks.

Methods: Pulp diagnosis was performed on 76 teeth with cracks according to the American Association of Endodontics's guidelines, and their QLF images were captured.

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Reducing Healing Period with DDM/rhBMP-2 Grafting for Early Loading in Dental Implant Surgery.

Tissue Eng Regen Med

January 2025

Department of Oral and Maxillofacial Surgery, Section of Dentistry, Seoul National University Bundang Hospital, 172 Dolma-ro, Bundang-gu, Seongnam-si, Gyeonggi-do, 13620, Republic of Korea.

Background: Traditionally, dental implants require a healing period of 4 to 9 months for osseointegration, with longer recovery times considered when bone grafting is needed. This retrospective study evaluates the clinical efficacy of demineralized dentin matrix (DDM) combined with recombinant human bone morphogenetic protein-2 (rhBMP-2) during dental implant placement to expedite the osseointegration period for early loading.

Methods: Thirty patients (17 male, 13 female; mean age 55.

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Intercellular mitochondria transfer is an evolutionarily conserved process in which one cell delivers some of their mitochondria to another cell in the absence of cell division. This process has diverse functions depending on the cell types involved and physiological or disease context. Although mitochondria transfer was first shown to provide metabolic support to acceptor cells, recent studies have revealed diverse functions of mitochondria transfer, including, but not limited to, the maintenance of mitochondria quality of the donor cell and the regulation of tissue homeostasis and remodelling.

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Tapered Submerged Implants in an Augmented Posterior Maxilla After Oroantral Fistula Closure.

J Craniofac Surg

November 2024

Department of Oral and Maxillofacial Surgery, Dental Research Institute, School of Dentistry, Seoul National University, Seoul, Korea.

Dental implantation in the posterior maxilla is challenging due to anatomic proximity to the sinuses, relative bone quality, and pre-existing sinus diseases. An oroantral fistula (OAF) acts as a pathologic pathway of bacteria and can cause sinus infections and complicate dental implant management. Bony augmentation between the sinus floor mucosa and the oral mucosa at the OAF closure site is another critical consideration.

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The Learning Curve in Urogynecology and Functional Urology: A Systematic Review.

Int Urogynecol J

January 2025

Research Center for Evidence-Based Medicine, Iranian EBM Centre: A JBI Centre of Excellence, Faculty of Medicine, Tabriz University of Medical Sciences, Attar-E-Neishabouri Sqr., Tabriz, 51666, Iran.

Introduction And Hypothesis: When adopting new methods, surgeons may experience a period of complexity and longer operation times because of their inexperience. This period is known as the "learning curve." This study was aimed at systematically reviewing the current literature on functional urology learning curves.

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Internally Submerged, Tapered, Bone-level Dental Implants in the Anterior Esthetic Region.

J Craniofac Surg

November 2024

Department of Oral and Maxillofacial Surgery, Dental Research Institute, School of Dentistry, Seoul National University, Seoul, Korea.

Background: Aesthetics is a crucial consideration in the anterior region, alongside dental implant survival and marginal bone loss (MBL). Bone-level implants are advantageous in the esthetic zone as they create a natural emergence profile with the use of customized abutments. This study aimed to assess the esthetic outcomes of internally submerged, tapered, bone-level dental implants and to evaluate associated alveolar bone changes.

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Outcome of Er, Cr:YSGG laser and antioxidant pretreatments on bonding quality to caries-induced dentin.

BMC Oral Health

January 2025

Conservative Dentistry Department, Faculty of Oral and Dental Medicine, Future University, Cairo, Egypt.

Background: This study aimed to assess the influence of different pretreatment protocols and antioxidants application on the shear bond strength (SBS) of universal adhesive to sound (SoD) and caries-induced dentin (CID).

Methods: One hundred and twenty posterior teeth had their occlusal enamel removed, then the specimens were divided into two main groups according to dentin substrates; SoD and CID, three subgroups according to pretreatments protocols control (no pretreatment), NaOCl-treated, and Er, Cr:YSGG-treated and two divisions according to antioxidant application (with and without sodium ascorbate (SA) application). All-Bond Universal (ABU) universal adhesives was applied in self-etch (SE) mode then resin composite discs were built.

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Obesity due to excessive body fat accumulation remains a global problem. Patients with obesity have high cortisol levels, and its dysregulation is caused by increased 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) levels. The effects and mechanism of J2H-1702, an 11β-HSD1 inhibitor, on nonalcoholic steatohepatitis (NASH) were explored.

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Parameter-Tuned Pulsed Wave Photobiomodulation Enhances Stem Cells From Apical Papilla Differentiation: Evidence From Gene and Protein Analyses.

J Biophotonics

January 2025

Department of Oral and Maxillofacial Surgery and Dental Research Institute, School of Dentistry, Seoul National University, Seoul, Republic of Korea.

This study examines the effects of pulsed wave photobiomodulation (pwPBM) on the osteogenic differentiation of stem cells from the apical papilla (SCAP). Using 810 nm near-infrared (NIR) light with 300 Hz pulses and a 30% duty cycle, pwPBM was applied at a total energy density of 750 mJ/cm. Osteogenesis was evaluated through both in vitro and in vivo analyses.

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This study aimed to develop an artificial intelligence (AI) model for the screening of degenerative joint disease (DJD) using temporomandibular joint (TMJ) panoramic radiography and joint noise data. A total of 2631 TMJ panoramic images were collected, resulting in a final dataset of 3908 images (2127 normal (N) and 1781 DJD (D)) after excluding indeterminate cases and errors. AI models using GoogleNet were evaluated with six different combinations of image data, clinician-detected crepitus, and patient-reported joint noise.

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Objectives: Considering the importance of patient-centered care, we aimed to evaluate the impact of systemic antibiotics on oral health-related quality of life during nonsurgical periodontal treatment. This controlled trial addresses a gap in understanding how systemic antibiotics influence patient-reported outcomes, focusing on Stage III periodontitis.

Materials And Methods: Sixty-one adults participated in a double-blind, randomized clinical trial, with participants divided into two groups: the test group, which received antibiotics, and the control group.

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Under-occlusion ('infraocclusion' as defined in the natural teeth) after implant restoration in the posterior area is commonly encountered in clinical practice; however, it has rarely been reported. Most importantly, the under-occlusion change mechanism remains unknown. The purpose of this case report was to analyze how the dentition of both arches changed in a patient, including teeth tilting, elongation and occlusal plane change with under-occlusion of the posterior implant restoration after long-term function.

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Comparison of osseointegration in commercial SLA-treated dental implants with different surface roughness: a pilot study in beagle dogs.

J Adv Prosthodont

December 2024

Department of Prosthodontics, Dental Research Institute, Dental and Life Sciences Institute, Education and Research Team for Life Science on Dentistry, School of Dentistry, Pusan National University, Yangsan, Republic of Korea.

Purpose: This pilot study investigated the effect of surface roughness on osseointegration by comparing two types of commercial SLA-treated dental implants with different surface roughness levels: moderately rough (S = 1 - 2 µm) and rough surfaces (S > 2 µm).

Materials And Methods: Two implant groups were studied: TS (rough surface) and ADD (moderately rough surface) groups. Surface characteristics were analyzed using optical profilometry and SEM.

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A Comparative Study of the Use of a 980 nm Diode Laser and 10600nm CO2 in the Treatment of Gingival Melanin Pigmentation.

J Lasers Med Sci

December 2024

Department of Periodontics, Dental Implants Research Center, Dental Research Institute, School of Dentistry, Isfahan University of Medical Sciences, Isfahan, Iran.

Gingival depigmentation with the help of lasers is known as an effective technique. The aim of this study was to compare the efficiency of 980nm diode and CO2 lasers in the treatment of gingival hyperpigmentation. In this clinical trial study, 14 individuals (8 females and 6 males) with the age range of 19 to 47 years were selected.

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Background: There is ample evidence showing the development of nystatin-resistant strains in patients undergoing malignancy treatment. Amphotericin B is a polyene antifungal drug that combines with ergosterol to cause cell death and is more effective on fungal species than routine antifungals such as nystatin. This study aimed to compare the effect of nystatin and amphotericin B on fungal species isolated from patients before and during head-and-neck radiotherapy.

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Background: Chronic apical periodontitis (AP) may influence the outcome of root canal treatment. Thus, it is important to diagnose AP using the best method available. This research was done to compare the diagnostic accuracy of parallel periapical radiography (PR) and different field of views (FOVs) of cone-beam computed tomography (CBCT).

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