Three-Dimensional Assessment of Dental Enamel Microcrack Progression After Orthodontic Bracket Debonding Using Optical Coherence Tomography.

The current study aimed to quantify the length progression of enamel microcracks (EMCs) after debonding metal and ceramic brackets, implementing OCT as a diagnostic tool. The secondary objectives included a three-dimensional assessment of EMC width and depth and the formation of new EMCs. OCT imaging was performed on 16 extracted human premolars before bonding and after debonding.

Effect of EGCG-Methacrylate-Functionalized Resin Infiltrant on White Spot Lesions: An In Vitro Study.

This study evaluated the color change (ΔE) and penetration depth (PD) of white spot lesions (WSLs) infiltrated with the resin infiltrant (Icon) functionalized with methacrylate epigallocatechin-3-gallate (EGCG). To introduce polymerizable double bonds, EGCG was reacted with methacryloyl chloride (EM). Subsequently, the Icon resin infiltrant (I) was loaded with neat EGCG (IE) or EGCG-methacrylate (IEM) at 2 wt% each.

Wear Resistance of Light-Cure Resin Luting Cements for Ceramic Veneers.

The purpose of this study was to compare the wear resistance of light-cure resin luting cements for veneers with that of other luting materials investigated in earlier studies. An Alabama wear-testing machine was used to measure the wear resistance of four recent light-cure resin luting cements for veneers (G-Cem Veneer; Panavia V5 LC; RelyX Veneer Cement; and Vario-link Esthetic LC). The volume loss ranged from 0.

Annotated Checklist of Poroid Hymenochaetoid Fungi in Central Asia: Taxonomic Diversity, Ecological Roles, and Potential Distribution Patterns.

Central Asia, located at the heart of Eurasia, is renowned for its varied climate and vertical vegetative distribution, which support diverse biomes and position it as a global biodiversity hotspot. Despite this ecological richness, Central Asia's fungal diversity, particularly wood-inhabiting macrofungi, remains largely unexplored. This study investigates the diversity, ecological roles, and potential distribution of poroid Hymenochaetoid fungi in the region.

Microspectrometer-Enabled Real-Time Concentration Monitoring in the Microfluidic Protein Enrichment Chip.

This study presents a novel microspectrometer-integrated microfluidic system for real-time protein concentration monitoring. The device employs electrokinetic principles for efficient protein preconcentration in a PDMS and Nafion film channel. Using FITC-labeled BSA as a model protein, the system demonstrated a linear correlation between protein concentration and absorbance at 491 nm.

Evaluating the Effectiveness of Patient-Centered Standardized Prophylaxis Processes in Enhancing Patient Satisfaction and Return Intentions.

This study aimed to evaluate the effectiveness of a patient-centered standardized prophylaxis process in improving patient satisfaction and intentions to return to dental clinics. Conducted in a first-tier city in China from 9 June to 26 July 2023, the cross-sectional survey included 826 patients from 38 dental clinics. Among the respondents, 438 received standardized prophylaxis services, while 388 were in the non-standardized group, with a mean age of 38.

Evaluation of Internal and Marginal Accuracy (Trueness and Precision) of Laminates Using DLP Printing and Milling Methods.

This study evaluated the internal and marginal accuracy (trueness and precision) of zirconia laminate veneers fabricated using the DLP printing and milling method, employing 3D analysis software program. The maxillary central incisor tooth of a typodont model was prepared by a dentist and scanned using a desktop scanner. An anatomical zirconia laminate was designed using computer-aided design (CAD) software and saved in a standard tessellation language (STL) format.

Clinical Outcomes and Complication Rates of Endodontically Treated Teeth with Fixed Dental Prostheses: A Retrospective Study.

: Endodontically treated teeth (ETT) often have significant structural damage and require multiple reinforcing methods during the reconstruction process. The aim of this study was to evaluate the complication rates of ETT with and without a post. : The study investigated various clinical factors, including technical complications as well as biological complications.

Efficacy of Rapid Salivary C-Reactive Protein Test to Assess Early Changes in Malignancy in the Oral Cavity and Its Utility in Screening for Oral Cancer.

The present study aimed to test the efficacy of the chair-side rapid salivary C-reactive protein assay kit in differentiating oral potentially malignant disorders (OPMDs) and oral cancer from normal mucosa using whole salivary samples. In this study, unstimulated saliva samples of cases (OPMDs and oral cancer) and controls (systemically healthy subjects) were used to detect CRP levels using a novel colorimetric, quantitative rapid assay kit. Kruskal-Wallis ANOVA with a post hoc Dunn's test were applied to determine the difference in the mean and SD values between the case and control groups.

Conceptual Knowledge of Oral Health Among Primary School Teachers in Riyadh, Saudi Arabia-A Cross Sectional Survey.

: School teachers need to have a better understanding of oral health aspects as schools serve as an effective environment for learning. Educators hold a significant position in conveying the importance they attribute to oral health in their lives. According to the World Health Organization, school teachers should include oral health promotion activities to evaluate students' oral health, track injuries, illnesses, and absenteeism related to oral health, advocate oral health prevention, and serve as role models.

Does Sex Matter in Obesity-Induced Periodontal Inflammation in the SS Mutant Rats?

The incidence of obesity has dramatically increased worldwide. Obesity has been shown to exacerbate the progression of periodontal disease. Studies suggest a sex difference in periodontitis, whereby males are more sensitive to periodontal inflammation compared to females.

Race to the Moon or the Bottom? Applications, Performance, and Ethical Considerations of Artificial Intelligence in Prosthodontics and Implant Dentistry.

This review aims to explore the applications of artificial intelligence (AI) in prosthodontics and implant dentistry, focusing on its performance outcomes and associated ethical concerns. Following the PRISMA guidelines, a search was conducted across databases such as PubMed, Medline, Web of Science, and Scopus. Studies published between January 2022 and May 2024, in English, were considered.

Novel Fast-Setting and Mechanically-Strong Calcium Phosphate Pulp-Capping Cement with Metformin Release to Enhance Dental Pulp Stem Cells.

Traditional pulp-capping materials like mineral trioxide aggregate (MTA) offer excellent biocompatibility and sealing, but limitations such as prolonged setting time, low bioactivity, and high costs persist. Metformin, with its potential in craniofacial regeneration, could enhance dentin synthesis by targeting pulp cells. This study aimed to: (1) develop a calcium phosphate cement with chitosan (CPCC) with improved physio-mechanical properties; (2) incorporate metformin (CPCC-Met) to assess release; and (3) evaluate human dental pulp stem cells (hDPSCs) response.

Semiconductor photocatalytic antibacterial materials and their application for bone infection treatment.

Bacterial infection in bone tissue engineering is a severe clinical issue. Traditional antimicrobial methods usually cause problems such as bacterial resistance and biosecurity. Employing semiconductor photocatalytic antibacterial materials is a more controlled and safer strategy, wherein semiconductor photocatalytic materials generate reactive oxygen species under illumination for killing bacteria by destroying their cell membranes, proteins, DNA, In this review, P-type and N-type semiconductor photocatalytic materials and their antibacterial mechanisms are introduced.

Technology usage and glycaemic outcomes in a single tertiary centre with an ethnically diverse and socioeconomically deprived cohort of children with type 1 diabetes mellitus.

Background: The UK National Paediatric Diabetes Audit (NPDA) data reports disparities in Haemoglobin A1c (HbA1c) levels among children and young people (CYP) with Type 1 Diabetes (T1D), with higher levels in those of Black ethnic background and lower socioeconomic status who have less access to technology. We investigate HbA1c differences in a T1D cohort with higher than national average technology uptake where > 60% come from an ethnic minority and/or socioeconomically deprived population.

Design & Methods: Retrospective cross-sectional study investigating the influence of demographic factors, technology use, and socioeconomic status (SES) on glycaemic outcomes.

Antibiotic exposure enriches streptococci carrying resistance genes in periodontitis plaque biofilms.

Background: Periodontitis is not always satisfactorily treated with conventional scaling and root planing, and adjunctive use of antibiotics is required in clinical practice. Therefore, it is important for clinicians to understand the diversity and the antibiotic resistance of subgingival microbiota when exposed to different antibiotics.

Materials And Methods: In this study, subgingival plaques were collected from 10 periodontitis patients and 11 periodontally healthy volunteers, and their microbiota response to selective pressure of four antibiotics (amoxicillin, metronidazole, clindamycin, and tetracycline) were evaluated through 16S rRNA gene amplicon and metagenomic sequencing analysis.

Impact of chlorine dioxide and chlorhexidine mouthwashes on friction and surface roughness of orthodontic stainless steel wires: an in-vitro comparative study.

Objectives: Good oral hygiene measures are important for successful orthodontic treatment. They involve various types of mouthwashes which have been reported to cause alteration of mechanical properties of archwires. This study aimed to evaluate the effects of a new kind of chlorine-dioxide-containing mouthwash on the mechanical properties and surface morphology of stainless steel orthodontic archwires against the already prevalent chlorhexidine mouthwash in the market.

Spatiotemporal regulation of alginate sub-structures at multiple scales revealed by monoclonal antibodies.

Alginates are abundant linear polysaccharides produced by brown algae and some bacteria. They have multiple biological roles and important medical and commercial uses. Alginates are comprised of D-mannuronic acid (M) and L-guluronic acid (G) and the ratios and distribution patterns of M and G profoundly impact their physiological and rheological properties.

Evaluation of exo-long noncoding RNA MALAT1 in OSCC in comparison to dysplastic and normal: A cross-sectional study.

Objective: This study explores the role of MALAT1 as a valuable target for creating minimally-invasive diagnostic methods and personalized treatments in the management of OSCC. It focuses on evaluating the role of exosomal MALAT1 in the progression of dysplasia to OSCC by influencing the PI3K/AKT pathway.

Method: This cross-sectional study evaluated MALAT1 expression and PI3K/AKT pathway components in exosomes derived from plasma samples of patients with various stages of oral dysplasia, OSCC and compared with normal.

Investigating the association of microRNA polymorphisms and lifestyle factors with the susceptibility to common gastrointestinal cancers in an Indian population- A case control study.

The cancers of the gastrointestinal (GI) tract have become a common diagnosis worldwide contributing to a large number of mortalities. Though potentially curable they are mostly fatal due to late diagnosis and lack of accurate diagnostic markers. microRNA, micromanagers of gene expression have been associated to have distinct roles as oncogenes or tumour suppressors in several cancers including GI cancers.

Assessment of oral health status among occupational chefs and pantry workers in Hyderabad city.

Background: The chefs and pantry workers environment plays a crucial role in the general and oral health. These workers have some unusual work timings and have a lot of stress and anxiety, and they also consume tobacco, alcohol, and smoke the cigarettes, which has a greater impact on oral health.

Material And Methods: A total of 86 kitchen workers (53 chefs and 33 pantry workers) of ten well-known restaurants in Hyderabad city were included.

Pivotal role of virulence genes in pathogenicity and vaccine development.

One of the most prevalent human infections is (), which affects more than half of the global population. Although infections are widespread, only a minority of individuals develop severe gastroduodenal disorders. The global resistance of to antibiotics has reached concerning levels, significantly impacting the effectiveness of treatment.

Photodynamic and photothermal bacteria targeting nanosystems for synergistically combating bacteria and biofilms.

The escalating hazards posed by bacterial infections underscore the imperative for pioneering advancements in next-generation antibacterial modalities and treatments. Present therapeutic methodologies are frequently impeded by the constraints of insufficient biofilm infiltration and the absence of precision in pathogen-specific targeting. In this current study, we have used chlorin e6 (Ce6), zeolitic imidazolate framework-8 (ZIF-8), polydopamine (PDA), and UBI peptide to formulate an innovative nanosystem meticulously engineered to confront bacterial infections and effectually dismantle biofilm architectures through the concerted mechanism of photodynamic therapy (PDT)/photothermal therapy (PTT) therapies, including in-depth research, especially for oral bacteria and oral biofilm.

The success rate of infrazygomatic mini-implants placed with and without surgical guides: a historical control study.

Background: To improve the success rate of mini-implants, some surgical guides have been developed through digital technologies to achieve three-dimensional (3D) guided mini-implants insertion. However, there is no a surgical guide which can be applied for the insertion of infrazygomatic mini-implant. In this study, we introduced a two-trajectories surgical guide and investigated the success rate of infrazygomatic mini-implants under the guidance of the template.

Fracture resistances of heat-treated nickel-titanium files used for minimally invasive instrumentation.

Background: This study compared the torsional resistance, bending stiffness, and cyclic fatigue resistances of different heat-treated NiTi files for minimally invasive instrumentation.

Methods: TruNatomy (TN) and EndoRoad (ER) file systems were compared with ProTaper Gold (PG). Torsional load, distortion angle, and bending stiffness were assessed using a custom device AEndoS, and toughness was calculated using the torsional data.