4 results match your criteria: "DenmarkDepartment of Clinical MedicineAalborg University[Affiliation]"

Maternal thyroid disease in the Danish National Birth Cohort: prevalence and risk factors.

Eur J Endocrinol

February 2016

Departments of EndocrinologyClinical BiochemistryAalborg University Hospital, Sdr. Skovvej 15, 9000 Aalborg, DenmarkDepartment of Clinical EpidemiologyAarhus University Hospital, 8000 Aarhus, DenmarkDepartment of Clinical MedicineAalborg University, 9000 Aalborg, Denmark Departments of EndocrinologyClinical BiochemistryAalborg University Hospital, Sdr. Skovvej 15, 9000 Aalborg, DenmarkDepartment of Clinical EpidemiologyAarhus University Hospital, 8000 Aarhus, DenmarkDepartment of Clinical MedicineAalborg University, 9000 Aalborg, Denmark.

Objective: Thyroid disorders are common in women of reproductive age, but the exact burden of disease before, during and after a pregnancy is not clear. We describe the prevalence of thyroid disease in women enrolled in the Danish National Birth Cohort (DNBC) and investigate some of its risk factors.

Design: Population-based study within the DNBC, which included 101,032 pregnancies (1997-2003).

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Hypothyroid symptoms and the likelihood of overt thyroid failure: a population-based case-control study.

Eur J Endocrinol

November 2014

Department of EndocrinologyAalborg University Hospital, DK-9000 Aalborg, DenmarkDiagnostic CentreRegion Hospital Silkeborg, Silkeborg, DenmarkDepartment of EndocrinologyBispebjerg University Hospital, Copenhagen, DenmarkDepartment of Internal MedicineSlagelse Hospital, Slagelse, DenmarkDepartment of Clinical MedicineAalborg University, Aalborg, Denmark Department of EndocrinologyAalborg University Hospital, DK-9000 Aalborg, DenmarkDiagnostic CentreRegion Hospital Silkeborg, Silkeborg, DenmarkDepartment of EndocrinologyBispebjerg University Hospital, Copenhagen, DenmarkDepartment of Internal MedicineSlagelse Hospital, Slagelse, DenmarkDepartment of Clinical MedicineAalborg University, Aalborg, Denmark.

Background: It is generally accepted that patients suffering from hypothyroidism may express few symptoms, but this has not been studied in a population-based study design.

Objectives: To study the array of symptoms as they are reported in newly diagnosed overt autoimmune hypothyroidism using a population-based case-control design.

Methods: Patients with new overt autoimmune hypothyroidism (n=140) and their individually matched thyroid disease-free controls (n=560) recruited from the same population underwent a comprehensive program and self-reported a number of symptoms.

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Antithyroid drugs and congenital heart defects: ventricular septal defect is part of the methimazole/carbimazole embryopathy.

Eur J Endocrinol

November 2014

Department of EndocrinologyAalborg University Hospital, Sdr. Skovvej 15, 9000 Aalborg, DenmarkDepartment of Clinical MedicineAalborg University, Aalborg, DenmarkDepartment of Clinical BiochemistryAalborg University Hospital, Aalborg, Denmark Department of EndocrinologyAalborg University Hospital, Sdr. Skovvej 15, 9000 Aalborg, DenmarkDepartment of Clinical MedicineAalborg University, Aalborg, DenmarkDepartment of Clinical BiochemistryAalborg University Hospital, Aalborg, Denmark.

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Therapy of endocrine disease: antithyroid drug use in early pregnancy and birth defects: time windows of relative safety and high risk?

Eur J Endocrinol

July 2014

Department of EndocrinologyAalborg University Hospital, DK-9000 Aalborg, DenmarkDepartment of Clinical MedicineAalborg University, Aalborg, DenmarkDepartment of EndocrinologyAalborg University Hospital, DK-9000 Aalborg, DenmarkDepartment of Clinical MedicineAalborg University, Aalborg, Denmark.

Background: Antithyroid drugs (ATDs) may have teratogenic effects when used in early pregnancy.

Objective: To review the association between the time period of ATD exposure in early pregnancy and the development of birth defects.

Methods: We identified publications on birth defects after early pregnancy exposure to the ATDs methimazole (MMI; and its prodrug carbimazole (CMZ)) and propylthiouracil (PTU).

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