319,717 results match your criteria: "Denmark ; The Buck Institute for Research on Aging[Affiliation]"
Glob Ment Health (Camb)
November 2024
Global Health Section, Department of Public Health, University of Copenhagen, Copenhagen, Denmark.
Evidence on the effectiveness and implementation of mental health and psychosocial support (MHPSS) interventions for men in humanitarian settings is limited. Moreover, engagement and retention of men in such interventions has been challenging. Adaptations may therefore be required to improve the appropriateness and acceptability of these interventions for men.
View Article and Find Full Text PDFJ Chiropr Med
December 2024
Department of Chiropractic, Université du Québec à Trois-Rivières, Trois-Rivières, Québec, Canada.
Objective: The objective of this study is to assess the methodological quality of the 2016 Society on Scoliosis Orthopaedic and Rehabilitation Treatment (SOSORT) guidelines for the detection and management of adolescent idiopathic scoliosis.
Methods: A diverse group of experts, including practicing chiropractors, chiropractors with a Diplomate by the American Chiropractic Board of Radiology, chiropractors with PhD degrees, and chiropractors involved in teaching within chiropractic programs was invited to participate in the study. Experts independently evaluated the guidelines using the Appraisal of Guidelines for Research and Evaluation II tool.
Brain Spine
January 2024
Medical University Vienna, Department of Biomedical Imaging and Image-Guided Therapy, Waehringer Guertel 18-20, A-1090, Vienna, Austria.
BBA Adv
September 2024
Interdisciplinary Nanoscience Center (iNANO), Aarhus University, Gustav Wieds Vej 14, DK-8000 Aarhus C, Denmark.
Neurooncol Pract
February 2025
Neurological Surgery, UCSF Weill Institute for Neurosciences, San Francisco, California, USA.
Pediatr Blood Cancer
January 2025
Department of Pediatrics and Adolescent Medicine, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark.
Diagnosing acute graft-versus-host disease (aGvHD) following allogeneic hematopoietic stem cell transplantation (HSCT) is challenging due to heterogeneity in interpreting current clinical criteria. Recently, the Mount Sinai Acute GvHD International Consortium (MAGIC) criteria were introduced to improve diagnostic consistency. In a study of 117 pediatric patients undergoing HSCT, the modified Glucksberg and the MAGIC criteria were retrospectively compared.
View Article and Find Full Text PDFJ Infect Dis
January 2025
Department of Clinical Medicine, Aarhus University, 8220 Aarhus, Denmark.
Heligmosomoides polygyrus co-infection is reported to have protective antiviral effects against pulmonary viral infections. To investigate a potential underlying mechanism, we infected C57BL/6 mice with H. polygyrus larvae for two weeks.
View Article and Find Full Text PDFHealth Promot J Austr
January 2025
Curtin University, Bentley, Western Australia, Australia.
Issue Addressed: Australian adults transitioning into retirement aged 55-75 years (> 50%) do not meet the World Health Organization recommendation of physical activity (PA). One potential strategy to promote PA is through vigorous intermittent lifestyle physical activity (VILPA). This study aimed to investigate barriers and facilitators from adults transitioning to retirement about participation in VILPA and to identify strategies to promote and implement VILPA.
View Article and Find Full Text PDFProbiotics Antimicrob Proteins
January 2025
Department of Virology, Pasteur Institute of Iran, Tehran, 13169-43551, Iran.
This review delves into the potential of antimicrobial peptides (AMPs) as promising candidates for combating arboviruses, focusing on their mechanisms of antiviral activity, challenges, and future directions. AMPs have shown promise in preventing arbovirus attachment to host cells, inducing interferon production, and targeting multiple viral stages, illustrating their multifaceted impact on arbovirus infections. Structural elucidation of AMP-viral complexes is explored to deepen the understanding of molecular determinants governing viral neutralization, paving the way for structure-guided design.
View Article and Find Full Text PDFJ Intern Med
January 2025
Department of Oncology, Aarhus University Hospital/Aarhus University, Aarhus, Denmark.
Background: This systematic review and meta-analysis assesses the association between metabolic syndrome and breast cancer (BC) outcomes in BC survivors.
Methods: Systematic searches were carried out in PubMed and Embase using variations of the search terms: breast neoplasms (population), metabolic syndrome (exposure), and survival (outcome). Metabolic syndrome was characterized according to the American Heart Association, which includes the presence of three out of five abnormal findings among the risk factors: high blood pressure, high triglycerides, low high-density lipoprotein, high fasting glucose, and central obesity.
Acta Paediatr
January 2025
Hans Christian Andersen Children's Hospital, Odense University Hospital, Odense, Denmark.
Aim: Homecare for neonates has advanced, but combative analysis of contact methods remains unexplored. The aim was to identify predictors of readmission during homecare and to compare home visit, telemedicine or outpatient visit.
Methods: This retrospective study included infants receiving homecare from 1 January 2015 to 31 December 2022.
Arch Dermatol Res
January 2025
Department of Dermatology, Hôpital Erasme, Université Libre de Bruxelles (ULB), Brussels, Belgium.
Hidradenitis suppurativa is an inflammatory skin disease for which adalimumab is an effective treatment in just over half of cases. Few factors associated with therapeutic response, and therefore potentially predictive of response, are known to date. This real-life study retrospectively explores the existence of such factors in a Belgian cohort of 82 patients, using several response scores: the Hidradenitis Suppurativa Clinical Response (HiSCR), the International Hidradenitis Suppurativa Severity Scoring System-55 (iHS4-55), and the dynamic metascore (a combination of the Hurley score, the 2007 version of the Sartorius score, the iHS4 and the HiSCR).
View Article and Find Full Text PDFEquine Vet J
January 2025
Department of Veterinary Clinical Sciences, University of Copenhagen, Taastrup, Denmark.
Background: MicroRNAs, a class of small noncoding RNAs, serve as post-transcriptional regulators of gene expression and are present in a stable and quantifiable form in biological fluids. MicroRNAs may influence intra-articular responses and the course of disease, but very little is known about their temporal changes in osteoarthritis.
Objectives: To identify miRNAs and characterise the temporal changes in their abundance in SF from horses with experimentally induced osteoarthritis.
J Clin Endocrinol Metab
January 2025
Department of Endocrinology and Internal Medicine, Aarhus University Hospital, Palle-Juul Jensens Boulevard 165, 8200 Aarhus N, Denmark.
Context: Few studies have reported on males with 45,X/46,XY mosaicism. Most studies stem from pediatric settings and knowledge of natural history and long-term health outcomes are therefore lacking.
Objective: To describe long-term health outcomes in males with 45,X/46,XY in comparison to the general population.
Plant Physiol
January 2025
Assistant Features Editor, Plant Physiology, American Society of Plant Biologists, Rockville, USA.
Bioinformatics
January 2025
Institute of Medical Systems Biology, Center for Biomedical AI (bAIome), Center for Molecular Neurobiology (ZMNH), University Medical Center Hamburg-Eppendorf, 20251, Hamburg, Germany.
Motivation: The identification of biologically meaningful domains is a central step in the analysis of spatial transcriptomic data.
Results: Following Occam's razor, we show that a simple PCA-based algorithm for unsupervised spatial domain identification rivals the performance of ten competing state-of-the-art methods across six single-cell spatial transcriptomic datasets. Our reductionist approach, NichePCA, provides researchers with intuitive domain interpretation and excels in execution speed, robustness, and scalability.
Ann Hum Genet
January 2025
Institute of Legal Medicine, Medical University of Innsbruck, Innsbruck, Austria.
Introduction: Southern Africa has been inhabited by hunter-gatherers for at least 20,000 years and has received diverse immigration flows in the last 2000 years. The original inhabitants have interacted with the pastoralist migrants from Eastern Africa (∼2000 ybp), followed by the southern Bantu migration arriving some 1000 ybp, and more recently with the European and Asian settlers after the 17th century. Many of the original Khoekhoe and San inhabitants have either become extinct or have disappeared through admixture in South Africa (SA), in a sex-biased manner involving KhoeSan women.
View Article and Find Full Text PDFTher Innov Regul Sci
January 2025
Global Patient Safety, Novo Nordisk A/S, Copenhagen, Søborg, 2860, Denmark.
The use of data monitoring committees (DMC) to safeguard patients' safety in clinical trials has evolved over the last decades and has become increasingly common. To ensure well-operating and high-performing DMCs, pharmaceutical companies need to establish clearly defined operational processes while continuously seeking to optimize these and adapt to the needs of drug development. Although there are health authority guidelines on establishing and managing a DMC, the perspectives and experiences of sponsors are often underrepresented.
View Article and Find Full Text PDFInt J Clin Pharm
January 2025
Department of Clinical Pharmacy, Leopold-Franzens Universität, Innsbruck, Austria.
Background: Drug-related problems (DRPs) are significant issues in healthcare contributing to adverse health outcomes and increased healthcare costs. While community pharmacists play a pivotal role in identifying, classifying, and documenting DRPs, there is a need to map approaches undertaken.
Aim: The aim of this scoping review was to examine the approaches to identifying, classifying, and documenting DRPs in community pharmacies in Europe, and their associated barriers and facilitators.
Curr Pain Headache Rep
January 2025
Department of Neurology, Danish Headache Center, Copenhagen University Hospital - Rigshospitalet, Valdemar Hansens Vej 5, Entrance 1A, 2600 Glostrup, Copenhagen, Denmark.
Purpose Of Review: To evaluate the available studies on structural magnetic resonance imaging (MRI) of post-traumatic headache (PTH).
Recent Findings: A systematic search of PubMed and Embase databases (from inception to February 1, 2024) identified nine relevant structural MRI studies. These studies included adult participants diagnosed with acute or persistent PTH in adherence with any edition of the International Classification of Headache Disorders.
PLoS One
January 2025
Ocean Frontier Institute, Department of Biology, Dalhousie University, Halifax, Nova Scotia, Canada.
Marine protected areas (MPAs) are widely used to conserve and manage coastal resources. Protected areas are governed by a variety of institutional arrangements, yet little is known concerning the relative performance of different governance approaches. This research draws upon a unique dataset that combines details on the reported International Union for Conservation of Nature (IUCN) governance categories of 217 global MPAs and their ecological outcomes to compare the performance of alternative governance arrangements.
View Article and Find Full Text PDFPLoS One
December 2024
Mwanza Research Centre, National Institute for Medical Research, Mwanza, Tanzania.
The increased burden of non-communicable diseases (NCDs) is fueled by lifestyle factors including diet. This cross-sectional study explored among Tanzanian adults whether unhealthy dietary patterns are associated with intestinal and systemic inflammation which could increase the risk of NCDs. The study included 574 participants, with both diet and inflammatory markers data.
View Article and Find Full Text PDFPLOS Glob Public Health
January 2025
Royal Danish Academy - Architecture, Design, Conservation, Copenhagen, Denmark.
Improved cooking stoves (ICS) are intended to reduce indoor air pollution and the inefficient use of fuel yet there is often reticence to shift permanently to ICS. Drawing on a scoping review, this article aims to provide a comprehensive overview of factors affecting the acceptability of ICS. A scoping review was carried out using a systematic search strategy of literature.
View Article and Find Full Text PDFSci Rep
January 2025
BESE Division, Plant Cell and Developmental Biology Laboratory, King Abdullah University of Science and Technology, Thuwal, Kingdom of Saudi Arabia.
In arid and semi-arid climates, native plants have developed unique strategies to survive challenging conditions. These adaptations often rely on molecular pathways that shape plant architecture to enhance their resilience. Date palms (Phoenix dactylifera) and mangroves (Avicennia marina) endure extreme heat and high salinity, yet the metabolic pathways underlying this resilience remain underexplored.
View Article and Find Full Text PDFSupport Care Cancer
January 2025
Department of Medical Oncology, Peter MacCallum Cancer Centre, Melbourne, Australia.
Background: Remote monitoring using electronic patient-reported outcomes (ePROs) may help identify immune-related adverse events (irAEs) and direct self-management. There is no consensus regarding thresholds to alert providers about potentially severe irAEs or when to instigate evidence-based self-management. We aimed to develop consensus around alert thresholds and self-management advice for side-effects suggestive of an irAE which can be deployed as part of remote monitoring systems.
View Article and Find Full Text PDF