Beyond perfect synchrony: shared interpersonal rhythmic timing enhances self-other merging judgements.

Perfect synchrony is highly prosocial, yet interpersonal rhythms globally exhibit rich variation. In two online experiments, we tested the effect of varying interpersonal rhythms on self-other merging. First, we hypothesized that shared temporal features, acting as attentional frameworks to track and integrate self-other actions, would drive combined representations.

Identifying species traits that predict vulnerability to climate change.

Accurately predicting the vulnerabilities of species to climate change requires a more detailed understanding of the functional and life-history traits that make some species more susceptible to declines and extinctions in shifting climates. This is because existing trait-based correlates of extinction risk from climate and environmental disturbances vary widely, often being idiosyncratic and context dependent. A powerful solution is to analyse the growing volume of biological data on changes in species ranges and abundances using process-explicit ecological models that run at fine temporal and spatial scales and across large geographical extents.

The late-Quaternary megafauna extinctions: Patterns, causes, ecological consequences and implications for ecosystem management in the Anthropocene.

Across the last ~50,000 years (the late Quaternary) terrestrial vertebrate faunas have experienced severe losses of large species (megafauna), with most extinctions occurring in the Late Pleistocene and Early to Middle Holocene. Debate on the causes has been ongoing for over 200 years, intensifying from the 1960s onward. Here, we outline criteria that any causal hypothesis needs to account for.

A Review on Energy Management System for Grid-Connected Utility-Scale Renewable Hybrid Power Plants.

In recent years, renewable hybrid power plants (HPPs) have experienced rapid expansion. Energy management systems (EMSs) are vital to these facilities, helping maximize economic returns for owners and shaping operational strategies across various time scales. However, a comprehensive review of advancements in this field is still lacking.

Severity of Achilles Tendinopathy on Preoperative MRI and Short-term Functional Outcomes After Minimally Invasive Zadek Osteotomy.

Background: Limited literature is available to guide surgeons on which patients with insertional Achilles tendinopathy (IAT) may be the best candidates for minimally invasive dorsal closing wedge calcaneal Zadek osteotomy (MIS ZO). We hypothesized that the severity of IAT on preoperative magnetic resonance image (MRI) may correlate with post-operative functional outcomes and help guide patient selection for treatment with MIS ZO.

Methods: Patients who underwent MIS ZO for IAT ± Haglund deformity were identified and retrospectively analyzed.

Riverine antibiotic resistome along an anthropogenic gradient.

The introduction of antibiotic-resistant bacteria into riverine systems through the discharge of wastewater treatment plant (WWTP) effluent and agricultural waste poses significant health risks. Even when not pathogenic, these bacteria can act as reservoirs for antibiotic resistance genes (ARGs), transferring them to pathogens that infect humans and animals. In this study, we used fluorescence hybridization, qPCR, and metagenomics to investigate how anthropogenic activities affect microbial abundance and the resistome along the Holtemme River, a small river in Germany, from near-pristine to human-impacted sites.

Fostering engagement using a wearable for self-tracking assisted psychotherapy with refugees diagnosed with complex PTSD: a feasibility pilot study.

Background: To address the unique challenges faced by refugees diagnosed with complex post-traumatic stress disorder (CPTSD), psychotherapy needs to be personalized. The integration of self-tracking instruments into therapy offers a promising approach to personalizing treatment. This feasibility pilot study develops and explores a preliminary self-tracking assisted treatment concept using a wearable self-tracking instrument called the One Button Tracker (OBT).

The isolated, perfused working heart preparation of the mouse-Advantages and pitfalls.

Isolated, perfused hearts are viable for hours outside the body, and important research findings have been made using mouse hearts ex vivo. In the Langendorff perfusion mode, the coronary tree is perfused via retrograde flow of a perfusate down the ascending aorta. Although the Langendorff setup is generally simpler and quicker to establish, the working heart mode allows the heart to function in a more physiologically relevant manner, where the perfusate is directed into the left ventricle via the left atrium.

The Impacts of Poor Sleep Quality on Knee Pain and Quality of Life in Young Adults: Insights from a Population-Based Cohort.

Objectives: Poor sleep is common among young adults and is often associated with pain. This study investigates the relationship between pain-related outcomes, sleep quality, and quality of life in young adults with and without knee pain.

Methods: This study is a secondary analysis of the 5-year follow-up of a prospective cohort study.

Time trends and predictors of difficulties in getting to sleep among adolescents from six Nordic countries 2002-2018.

Aims: Sleep difficulties among adolescents are of a significant concern given its associations with adverse health outcomes. The aims of the present study were to examine trends and predictors of self-perceived difficulties in getting to sleep among adolescents in the Nordic countries.

Methods: The study was based on cross-sectional data from 10- to 17- year-olds ( = 139,799) from six Nordic countries (Sweden, Iceland, Norway, Denmark, Greenland, and Finland) participating in the international Health Behaviour in School-aged Children (HBSC) study, collected via six survey rounds in the period 2002-2018.

Drivers of Epilithic Biofilms in Greenland Streams: The Role of Nutrients, Temperature and Catchment Slope Across a Climate Gradient.

The Arctic is warming faster than the global average, making it critical to understand how this affects ecological structure and function in streams, which are key Arctic ecosystems. Microbial biofilms are crucial for primary production and decomposition in Arctic streams and support higher trophic levels. However, comprehensive studies across Arctic regions, and in particular within Greenland, are scarce.

Recent Advances in Processing-Induced Changes in the Structure, Techno-Functional Properties and Nutritional Quality of Animal- and Plant-Based Food Proteins.

Proteins are essential macronutrients in the human diet and key structural constituents of many food products [...

Vagus Nerve Mediated Liver-Brain-Axis Is a Major Regulator of the Metabolic Landscape in the Liver.

The liver serves as a major energetic reservoir for other tissues and its metabolic function is controlled by humoral and neural factors. The vagus nerve innervating the gastrointestinal tract plays an important role in regulating peripheral metabolism and energy expenditure. Although the liver receives vagus nerve fibers, the impact of this circuitry in the regulation of hepatic metabolism is still poorly understood.

DNA Salivary Methylation Levels of the ACE2 Promoter Are Not Related to ACE2 ( and ), TMPRSS2 ( and ) and ACE1 Polymorphisms in COVID-19 Survivors with Post-COVID-19 Condition.

Genetics and epigenetics are mechanisms proposed for explaining post-COVID-19 condition. This secondary analysis aimed to investigate if DNA methylation levels of the ACE2 promoter are different depending on the genotype of five COVID-19-related polymorphisms in individuals who had been previously hospitalized due to SARS-CoV-2 infection. We collected non-stimulated saliva samples from 279 (48.

Neurons Co-Expressing GLP-1, CCK, and PYY Receptors Particularly in Right Nodose Ganglion and Innervating Entire GI Tract in Mice.

Afferent vagal neurons convey gut-brain signals related to the mechanical and chemical sensing of nutrients, with the latter also mediated by gut hormones secreted from enteroendocrine cells. Cell bodies of these neurons are located in the nodose ganglia (NG), with the right NG playing a key role in metabolic regulation. Notably, glucagon-like peptide-1 receptor (GLP1R) neurons primarily innervate the muscle layer of the stomach, distant from glucagon-like peptide-1 (GLP-1)-secreting gut cells.

Development and Assessment of a Multiple-Analysis System for Diagnosing Malaria and Other Blood Parasite Infections in Humans and Non-Human Primates.

: Many tropical diseases such as malaria, Chagas, human African Trypanosomiasis, and Lymphatic filariasis coexist in endemic countries, affecting more than 1 billion people worldwide, and are recognised as major global vector-borne diseases. Tackling this disease requires an accurate diagnosis that is sensitive, specific, and rapid. This study aimed to describe and validate a new highly sensitive and specific multiple-analysis system that can effectively detect numerous etiological agents in a single test.

Aortic Root Replacement Procedures: A Validation Study of the Western Denmark Heart Registry from 1999 to 2022.

: We reviewed data from the Western Danish Heart Registry (WDHR), which collects mandatory information on heart surgeries in Western Denmark, to validate cases with aortic root replacement (ARR) and assess the validity of registered data for all recorded cases. : Patients registered in the WDHR with Danish Health Care Classification System (SKS) codes KFC and KFM from January 1999 to April 2022 were reviewed using electronic medical records. All patients who underwent ARR were included, and clinical data from the WDHR were adjudicated against electronic medical records.

Is the Transverse Colon Overlooked? Establishing a Comprehensive Colonoscopy Database from a Multicenter Cluster-Randomized Controlled Trial.

Colonoscopy holds the highest volume of all endoscopic procedures, allowing for large colonoscopy databases to serve as valuable datasets for quality assurance. We aimed to build a comprehensive colonoscopy database for quality assurance and the training of future AIs. As part of a cluster-randomized controlled trial, a designated, onsite medical student was used to acquire procedural and patient-specific data, ensuring a high level of data integrity.

The Impact of the Localization of Metastasis in Bladder Cancer Patients with Recurrence After Cystectomy.

The aim of this study is to assess the prognostic implications of metastatic anatomical location in patients with recurrent bladder cancer (BC) after cystectomy. The study is a retrospective cohort study. All data were collected from a clinical database from Aarhus University Hospital.

Management Based on Pretreatment PSMA PET of Patients with Localized High-Risk Prostate Cancer Part 2: Prediction of Recurrence-A Systematic Review and Meta-Analysis.

Background And Objectives: For patients with prostate cancer (PCa), PSMA PET better diagnose metastases than conventional imaging. In a systematic review and meta-analysis (INPLASY register, 2024311004), we aimed to summarize findings with pretreatment PSMA PET in patients with PCa that was localized according to conventional imaging and summarize how pretreatment PSMA PET had influence on biochemical recurrence (BCR)-free survival and overall survival (OS).

Methods: We searched for publications in Pubmed, Google Scholar, ClinicalTrials.

Development of a Scoring Instrument for Identification of Pneumonitis in Older Lung Cancer Patients After Radiotherapy (POLCAR): A Protocol for a Prospective Trial.

: Pneumonitis caused by radiotherapy for lung cancer may be missed since it often occurs only several months later. In a previous trial including patients of any age, a scoring system was tested to facilitate the correct diagnosis of radiation pneumonitis. Since elderly lung cancer patients have a greater risk of developing this complication, a separate scoring system for this group appears useful.

Robust vs. Non-robust radiomic features: the quest for optimal machine learning models using phantom and clinical studies.

Purpose: This study aimed to select robust features against lung motion in a phantom study and use them as input to feature selection algorithms and machine learning classifiers in a clinical study to predict the lymphovascular invasion (LVI) of non-small cell lung cancer (NSCLC). The results of robust features were also compared with conventional techniques without considering the robustness of radiomic features.

Methods: An in-house developed lung phantom was developed with two 22mm lesion sizes based on a clinical study.

Convergence of neurodegeneration and the arts: a conversation between researchers about stigma, co-creativity, and transformation.

Parkinson's disease and dementia are highly stigmatized, creating social exclusion and inequality by depriving persons living with these conditions of their human rights and threatening their health, well-being, and quality of life. Challenging the stigma associated with these conditions is a key public health priority across national and international settings, and arts-based approaches are advocated to achieve this. We are researchers who use artistic and creative media including documentary films, research-based theatre, dance, circus and graphic narrative to challenge dominant and oppressive cultural and social norms, and to imagine and affect inclusive, compassionate, and socially-just approaches to supporting people to live well with neurodegenerative conditions like dementia and Parkinson's.

Lumbar round cell sarcoma in a 10-week-old rottweiler puppy.

Background: Spinal neoplasms are sparsely documented in juvenile dogs. Case reports and small case series have described nephroblastomas, primitive neuroectodermal tumours, gliomas, certain sarcomas, and osteochondromas, but round cell sarcomas have not previously been documented.

Case Presentation: This case report describes a 10-week-old female Rottweiler puppy with acute onset of progressive ataxia and pelvic limb lameness.

Four scales measuring mental wellbeing in the Nordic countries: do they tell the same story?

Background: Mental wellbeing is an important focus in surveys among adolescents. Several relevant instruments are available. In the Nordic part of the Health Behaviour in School-aged Children (HBSC) study 2022, four different scales for the measurement of wellbeing, were employed: Cantril's Ladder, the WHO-5 Wellbeing Index, the seven-item Short Warwick-Edinburgh Mental Wellbeing Scale (SWEMWBS), and the HBSC Health Complaints Scale.