576 results match your criteria: "Demodicosis"

Canine T zone lymphoma is a tumor of mature, previously activated αβ T cells.

Vet Immunol Immunopathol

March 2024

Clinical Hematopathology Laboratory, Department of Microbiology, Immunology and Pathology, College of Veterinary Medicine and Biomedical Science, Colorado State University, Fort Collins, CO 80523, United States. Electronic address:

T cell lymphomas are a diverse group of tumors found in both dogs and humans, originating from various normal T cell types. Identifying the origin of neoplastic lymphocytes can offer valuable insights into the pathogenesis and clinical behavior of these tumors. T zone lymphoma (TZL) in dogs is characterized by the absence of CD45 expression, a strong breed predilection, and its association with adult-onset demodicosis-a condition believed to be linked to immunosuppression.

View Article and Find Full Text PDF

The Association Between Acne Vulgaris, Acne Vulgaris with Nonspecific Facial Dermatitis, and Mite Presence.

Clin Cosmet Investig Dermatol

January 2024

School of Anti-Aging and Regenerative Medicine, Mae Fah Luang University, Bangkok, Thailand.

Article Synopsis
  • The study investigates the role of mites in skin disorders, particularly focusing on individuals with acne vulgaris, acne with nonspecific dermatitis, and those with healthy skin, to clarify any associations.
  • 120 participants aged 18-37 were examined, and standard biopsy methods were used to detect mites across the three groups, emphasizing the importance of accurate diagnosis by the same dermatologist.
  • Results showed no significant mite prevalence in patients with acne vulgaris alone compared to healthy controls, but a higher prevalence in those with acne and nonspecific dermatitis, revealing a link between skin symptoms and mite presence.
View Article and Find Full Text PDF

Background: In January 2021, a female 1-year-old Kunekune was presented at the University Clinic for Swine with severe reduction of the field of vision resulting in prolonged reaction time when targeting barriers, due to moderate to severe thickening of the skin around both orbits also affecting the eyelids.

Methods: Clinical examination revealed skin hyperplasia, nodular enlargement of the skin pores of the axillar and inguinal region. Ophthalmologists decided to remove parts of the thickened periocular skin, followed by histopathological examination.

View Article and Find Full Text PDF

Background: Human Demodex mites, Demodex folliculorum and Demodex brevis, are microorganisms that reside in the pilosebaceous units, usually without causing symptoms. Phototherapy has been linked to demodicosis in previous studies. We aimed to determine whether there was an increase in the frequency of demodicosis and Demodex density after 20 phototherapy sessions.

View Article and Find Full Text PDF

Diseases vary among and within species but the causes of this variation can be unclear. Immune responses are an important driver of disease variation, but mechanisms on how the body resists pathogen establishment before activation of immune responses are understudied. Skin surfaces of mammals are the first line of defense against abiotic stressors and pathogens, and skin attributes such as pH, microbiomes, and lipids influence disease outcomes.

View Article and Find Full Text PDF

Topical ivermectin 1.0% cream in the treatment of ocular demodicosis.

Cont Lens Anterior Eye

February 2024

School of Optometry, College of Health and Life Sciences, Aston University, Birmingham, United Kingdom; School of Optometry and Vision Science, Faculty of Medicine and Health, University of New South Wales, Sydney, Australia. Electronic address:

Article Synopsis
  • Ocular demodicosis can severely affect eye health, and this study explored the use of topical ivermectin 1.0% cream to treat it, given its effectiveness for similar issues in rosacea.
  • The research involved analyzing patient records, with 75 participants receiving nightly applications of the cream over three months, and assessments were made before treatment and at two follow-up appointments.
  • Results showed significant improvements, with marked reductions in signs of demodicosis, including fewer lash collarettes and signs of Demodex, indicating that ivermectin is effective for this condition, though further studies are needed for better management.
View Article and Find Full Text PDF

Case Series of Demodicosis in Acne Vulgaris Patients.

Clin Cosmet Investig Dermatol

November 2023

Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.

An abnormal density of mites can trigger many skin disorders known as demodicosis. Clinical manifestations of demodicosis may resemble other skin diseases and can coexist with other skin disorders, resulting in underdiagnosis and a more challenging diagnosis. Here, we report three cases of demodicosis in acne vulgaris patients.

View Article and Find Full Text PDF

Bullous presentation of demodicosis in a young immunocompetent patient.

Int J Dermatol

January 2024

Department of Dermatology, Reference Center for Auto-immune Bullous Diseases, Avicenne University Hospital, AP-HP, Sorbonne-Paris-Nord University, Bobigny, France.

View Article and Find Full Text PDF

Purpose: The study comparatively evaluates the effectiveness of various approaches to acaricidal treatment in patients with chronic demodex blepharitis and meibomian gland dysfunctions.

Material And Methods: The study included 40 patients with chronic blepharitis (CB) of demodicosis etiology in conditions of meibomian gland dysfunction (MGD) and dry eye (DE). The 1 group of patients (20 people) received acaricidal treatment as part of therapeutic eyelid hygiene (TEH; 2 times a day) involving the use of «Blefarogel ochishchenie», «Blefarolosion», «Blefarogel forte» (contains sulfur and metronidazole).

View Article and Find Full Text PDF

Development of Demodicosis after Omalizumab Injection.

Ann Dermatol

May 2023

Department of Dermatology, Severance Hospital, Cutaneous Biology Research Institute, Yonsei University College of Medicine, Seoul, Korea.

View Article and Find Full Text PDF

The varied influence of ocular Demodex infestation on dry eye disease and meibomian gland dysfunction across different age groups.

Sci Rep

September 2023

Department of Ophthalmology, Chung-Ang University College of Medicine, Chung-Ang University Hospital, 102 Heukseok-ro, Dongjak-gu, Seoul, 06973, Republic of Korea.

This study aimed to investigate the impact of ocular demodicosis on dry eye disease (DED) and meibomian gland dysfunction (MGD) across different age populations: young (20 to < 40), middle-aged (40 to < 60), and elderly (≥ 60), based on the retrospective medical chart review. In each age subgroup, Demodex infestation and its count were correlated with clinical parameters of DED and MGD. Among the total of 351 subjects, 52.

View Article and Find Full Text PDF

Species and Culturable Microorganism Co-Infestations in Patients with Blepharitis.

Life (Basel)

August 2023

Independent Laboratory of Pharmaceutical Botany, Pomeranian Medical University, al. Powstańców Wielkpolskich 72, 70-111 Szczecin, Poland.

We aimed to determine the prevalence of spp. and bacterial infection in patients with blepharitis and also to investigate the relationship between culturable microorganisms and spp. in this study.

View Article and Find Full Text PDF

Comorbidity of Ocular and Facial Demodicosis.

Am J Ophthalmol

January 2024

Department of Ophthalmology, National Taiwan University Hospital, College of Medicine, National Taiwan University (F.-R.H.), Taipei, Taiwan. Electronic address:

Purpose: To determine the association between ocular and facial demodicosis, and the effect of facial treatment on ocular demodicosis.

Design: Prospective clinical cohort study.

Methods: Ocular demodicosis outpatients from a tertiary medical center were enrolled from April to December 2020.

View Article and Find Full Text PDF

Background: Canine generalized demodicosis is an inflammatory skin disease, which usually has time-consuming and frustrating treatments.

Aim: The present study aimed to evaluate the acaricidal activity of carvacrol as a green drug and a combination of carvacrol and amitraz on mites and investigate mites' survival lifetime.

Methods: Mite samples were collected from a dog affected by demodicosis and had been diagnosed with deep skin scrapings.

View Article and Find Full Text PDF

Rosacea in children: a review.

Eur J Pediatr

October 2023

Department of Dermatology and Allergology, Städtisches Klinikum Dresden, Academic Teaching Hospital, Friedrichstrasse 41, 01067, Dresden, Germany.

Unlabelled: Rosacea is a facial inflammatory disorder that shows an increasing incidence with age. While rosacea is common > 60 years of age, pediatric rosacea is uncommon. Diagnostic criteria are based on clinical symptoms.

View Article and Find Full Text PDF

MedGAN: An adaptive GAN approach for medical image generation.

Comput Biol Med

September 2023

School of Computer Science and Engineering, Hunan University of Arts and Sciences, Changde 415000, China.

Generative adversarial networks (GANs) and their variants as an effective method for generating visually appealing images have shown great potential in different medical imaging applications during past decades. However, some issues remain insufficiently investigated: many models still suffer from model collapse, vanishing gradients, and convergence failure. Considering the fact that medical images differ from typical RGB images in terms of complexity and dimensionality, we propose an adaptive generative adversarial network, namely MedGAN, to mitigate these issues.

View Article and Find Full Text PDF
Article Synopsis
  • The study investigates the effectiveness of various Thai herbal essential oils, tea tree oil, and metronidazole against skin mites associated with demodicosis and rosacea.
  • Results show that lemongrass oil was the most effective, followed by other herbal oils, while ivermectin and metronidazole were less effective.
  • The findings suggest that Thai herbal essential oils could serve as potential alternative therapies for mite-related skin disorders, but further research is needed to confirm their effectiveness and safety in live subjects.
View Article and Find Full Text PDF

Application of machine learning models to animal health pharmacovigilance: A proof-of-concept study.

J Vet Pharmacol Ther

November 2023

Elanco Animal Health, Form 2, Bartley Way, Bartley Wood Business Park, Hook, RG27 9XA, UK.

Article Synopsis
  • A proof-of-concept study explored the use of machine learning (ML) models on pharmacovigilance (PV) data by dividing it into training, validation, and holdout datasets.
  • In the first component, ML models successfully identified specific risk factors linked to spinosad-related neurological and ocular clinical signs based on individual case safety reports (ICSRs).
  • The second component focused on distinguishing high-quality ICSRs from those with confounders, where the model achieved over a 10-fold increase in probability score for identifying the correct report, indicating promise for future applications of ML in animal health PV.
View Article and Find Full Text PDF

Videodermoscopy in the Assessment of Patients With Ocular Demodicosis.

Dermatol Pract Concept

April 2023

Department of Dermatology, Venereology and Allergology, Faculty of Medicine, Medical University of Gdańsk, Gdańsk, Poland.

Introduction: There is growing evidence of the potential uses of dermoscopy in diagnostics of demodicosis. No previous studies have analyzed dermoscopic features in patients with ocular demodicosis.

Objectives: To evaluate the potential usefulness of videodermoscopy in diagnostics of ocular demodicosis.

View Article and Find Full Text PDF
Article Synopsis
  • Demodex folliculorum is a common skin parasite that lives in hair follicles and sebaceous glands, and its connection to skin diseases is known, but there's little information on its role in skin pigmentation issues.
  • A case study is presented about a 35-year-old Saudi male with facial hyperpigmentation caused by Demodex, who was being treated with immunosuppressive drugs.
  • The patient was effectively treated with ivermectin 1% cream, showing significant improvement after three months, highlighting the need to consider Demodex as a cause of facial hyperpigmentation that can be diagnosed and managed easily.
View Article and Find Full Text PDF