576 results match your criteria: "Demodicosis"
Evaluating the Efficacy of Oral Ivermectin on Clinical Symptoms and x Densities in Patients with Demodicosis.
Drug Des Devel Ther
November 2024
School of Anti-Aging and Regenerative Medicine, Mae Fah Luang University, Bangkok, Thailand.
Article Synopsis
- Dermatologists struggle with treating demodicosis due to its recurrence and difficulty in normalizing densities even after improvement.
- The study evaluated the effectiveness of oral ivermectin (200 µg/kg/week) in improving clinical symptoms and reducing density in 40 demodicosis patients, comparing those with lower and higher densities.
- Results showed 75% of patients achieved clinical remission, with quicker remission for patients with lower densities (28 days) compared to those with higher densities (56 days).
Clinical and epidemiological characterization of demodicosis cases in the pediatric population at the Hospital Clinic of the University of Chile (2013‒2020).
An Bras Dermatol
November 2024
Clinical Laboratory Service, Microbiology Unit, Hospital Clínico Universidad de Chile, Santiago, Chile.
Efficacy of a chewable tablet containing sarolaner, moxidectin and pyrantel for the treatment of generalised demodicosis in dogs.
Vet Dermatol
October 2024
Zoetis, Veterinary Medicine Research and Development, Kalamazoo, Michigan, USA.
Background: Demodicosis is common in dogs and is caused by proliferation of commensal Demodex canis mites.
Objective: To evaluate the efficacy of sarolaner in combination with moxidectin and pyrantel (SMP) for the treatment of generalised demodicosis in dogs.
Animals: One hundred and thirty dogs with generalised demodicosis.
Demodicosis in an Immunocompetent Child.
J Pediatr
January 2025
Parasitology-Mycology Department, Avicenne Hospital, AP-HP, Bobigny, Sorbonne Paris Nord University, France; Unité des Virus Émergents (UVE: Aix-Marseille Université-IRD 190-Inserm 1207-IHU Méditerranée Infection), Marseille, France.
Investigation of Factors Associated with Gut Microbiota in -associated Skin Conditions.
Turkiye Parazitol Derg
October 2024
Dokuz Eylül University Hospital, Department of Dermatology, İzmir, Türkiye.
Article Synopsis
- This study examines the links between gut microbiota factors and skin conditions like demodicosis, rosacea, and perioral dermatitis in 113 patients.
- Researchers found that alcohol consumption and smoking were significant risk factors for these skin issues, along with low water intake and infrequent exercise.
- The findings suggest that environmental and lifestyle choices can influence these skin conditions, highlighting the need for further exploration into their management and potential treatments.
The Prevalence of spp. Infestation in Dermatological Patients in Northern Poland.
Life (Basel)
September 2024
Department of Dermatology, Venereology and Allergology, Medical University of Gdańsk, University Clinical Centre, 80-214 Gdańsk, Poland.
Article Synopsis
- - The study examined the prevalence of *spp.* mites in 2508 patients from northern Poland suspected of having demodicosis, with a total of 3684 tests conducted.
- - Only 43.02% of the tests confirmed the presence of *spp.*, showing a positive correlation with the patient's age and higher detection rates on eyelids and facial skin.
- - Men were found to have *spp.* more often than women, and effective diagnosis of demodicosis remains challenging due to vague symptoms and low confirmation rates, particularly among younger patients.
Die-off reaction of mites after treating demodicosis with oral ivermectin: A case report.
JAAD Case Rep
October 2024
Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.
Successful Treatment of Angiolymphoid Hyperplasia with Eosinophilia Associated with Scalp Demodicosis Using Cryotherapy and Topical Metronidazole.
Sultan Qaboos Univ Med J
August 2024
Department of Histopathology, Royal Hospital, Muscat, Oman.
Article Synopsis
- Angiolymphoid hyperplasia with eosinophilia (ALHE) is a rare, benign tumor that was diagnosed in a 25-year-old female patient with distinctive skin lesions on her scalp.
- A biopsy confirmed the diagnosis of ALHE and revealed an infestation of Demodex mites in her sebaceous glands.
- The patient's condition improved significantly after 7 weeks of treatment involving cryotherapy and the topical use of metronidazole gel, suggesting that Demodex mites might play a role in triggering ALHE.
Dermoscopy as a clinical tool for the diagnosis of demodicosis: a retrospective intrapatient case-control study.
Arch Dermatol Res
August 2024
Department of Dermatology, Escuela de Medicina, Pontificia Universidad Católica de Chile, 4686 Vicuña Mackenna Avenue, Macul, Santiago de Chile, Chile.
Article Synopsis
- Dermoscopy is being evaluated as a non-invasive method to diagnose demodicosis, but previous studies vary in their testing standards and positivity criteria.
- A study reviewed 64 patients, comparing dermoscopic findings with skin scraping results, and found a strong correlation between certain dermoscopic signs (like Demodex tails) and the presence of mites, suggesting dermoscopy could be sufficient for diagnosis.
- The study calculated performance indicators showing that specific dermoscopic signs have high positive likelihood ratios, indicating they could reliably indicate demodicosis.
Pigmented Demodicosis: Non-Invasive Skin Imaging of a Rare Entity.
Dermatol Pract Concept
July 2024
Dermatology Unit, Department of Clinical Internal Anesthesiologic Cardiovascular Sciences, Sapienza University of Rome, Rome, Italy.
Non-Invasive Paraclinical Diagnosis of Hepatocutaneous Syndrome in a Dog.
Life (Basel)
July 2024
Internal Medicine Clinic, Faculty of Veterinary Medicine, Iași University of Life Sciences, 8 M. Sadoveanu Alley, 700489 Iași, Romania.
Article Synopsis
A New Complication Reported for the First Time After Rhinoplasty: Demodicosis.
Turkiye Parazitol Derg
June 2024
Kastamonu University Faculty of Medicine, Department of Dermatology, Kastamonu, Türkiye.
Beyond the Surface: Understanding Demodex and Its Link to Blepharitis and Facial Dermatoses.
Clin Ophthalmol
June 2024
Multidisciplinary Integrated Center of Dermatological Interface Research MIC-DIR, "Dunarea de Jos" University, Galaţi, Romania.
Article Synopsis
- Demodex mites are the most common ectoparasites found on humans and usually coexist harmlessly in hair follicles and oil glands.
- However, if their population increases excessively, they can lead to various eye issues (like blepharitis and ocular rosacea) and skin conditions (such as rosacea and seborrheic dermatitis).
- Recognizing the role of Demodex in these conditions is vital for proper diagnosis and treatment, which may include specific therapies aimed at reducing the mite population and alleviating symptoms.
Unilateral demodicidosis of the nipple/areola complex mimicking nevoid hyperkeratosis.
JAAD Case Rep
July 2024
Division of Clinical Dermatology, Università Vita-Salute San Raffaele, IRCCS Ospedale San Raffaele, Milano, Italy.
Evaluation of the relationship between Demodex infestation and obesity in rosacea patients.
J Cosmet Dermatol
October 2024
Ankara Training and Research Center, Department of Dermatology and Venerology, Health Sciences University, Ankara, Turkey.
Background: The changes in the skin caused by obesity may predispose patients with rosacea to Demodex infestation (DI). Besides, identifying predisposing factors in these patients is important for initial treatment plan.
Aims: The main purpose of this study is to determine the relationship between DI and obesity in patients with rosacea.
[Translated article] Jarisch-Herxheimer Reaction to Topical Ivermectin in Demodicosis?
Actas Dermosifiliogr
July 2024
Servicio ITS/Dermatología, Ayuntamiento de Madrid, Spain.
Relationship between surgical rhinoplasty and Demodex infestation: a case-control study.
Turk J Med Sci
May 2024
Department of Plastic, Reconstructive and Aesthetic Surgery, Faculty of Medicine, Kocaeli University, Kocaeli, Turkiye.
Article Synopsis
- Human Demodex mites can cause a skin condition called demodicosis, and this study explores whether surgical rhinoplasty, a common cosmetic surgery, increases the risk of infection by these parasites.
- The research compared 50 rhinoplasty patients to 50 healthy controls by collecting skin samples from their noses to measure Demodex density.
- Results showed that rhinoplasty patients had significantly higher levels of Demodex mites and more skin issues like dryness and pustules, suggesting that rhinoplasty may make patients more vulnerable to demodicosis but can be managed with the right treatment.
Which factors influence Demodex mite density in standardized superficial skin biopsy in patients with rosacea? A prospective cross-sectional analysis.
Arch Dermatol Res
May 2024
Dermatology and Venereology, Sisli Hamidiye Etfal Training and Research Hospital, Istanbul, Turkey.
Rosacea is a chronic cutaneous disease that manifests with facial erythema, telangiectasia, papules and pustules on the central face. Although the pathogenesis is not well established, rosacea appears to have a close relationship with Demodex mites. The aim of the study was to elucidate the factors influencing Demodex mite density by standardized superficial skin biopsy (SSSB) in patients with rosacea.
View Article and Find Full Text PDFSuccessful treatment of non-pruritus, excessive hair shedding and scales in a cat due to with fluralaner topical spot-on.
JFMS Open Rep
May 2024
Department of Companion Animal Clinical Sciences, Faculty of Veterinary Medicine, Kasetsart University, Bangkok, Thailand.
Article Synopsis
- * Dermatological exams revealed no pathogens, leading to the treatment of the cat with fluralaner (Bravecto) and a fatty acid supplement, resulting in significant improvement after 4 weeks.
- * This case is notable for diagnosing demodicosis without itchiness and successfully treating it with fluralaner in a new off-label application.
Demodicosis in a Free-Ranging Eurasian Brown Bear (Ursus arctos arctos) Cub in the Endangered Cantabrian Population, Spain.
J Wildl Dis
July 2024
Departament de Medicina i Cirurgia Animals, Facultat de Veterinària, Universitat Autónoma de Barcelona, 08193-Bellaterra, Barcelona (Cataluña), España.
A free-living female Cantabrian brown bear (Ursus arctos arctos) cub severely affected by mange in Asturias (northern Spain) represented the first report of demodicosis for this species. After antimicrobial, antiparasitic, anti-inflammatory, and analgesic therapy it recovered and was released back into the wild to the eastern Cantabrian brown bear subpopulation.
View Article and Find Full Text PDF"Demodicosis" Mimicking PreSeptal Cellulitis: Severe Periocular and Facial Inflammation Caused by "Normal" Skin Flora.
Ophthalmic Plast Reconstr Surg
May 2024
Surgical Service, Division of Ophthalmology, Veterans Affairs Healthcare System, Boston, Massachusetts, U.S.A.
Article Synopsis
- Demodex mites, often debated for their harmful effects, are now linked to various skin and eye diseases, including rosacea and keratitis.
- A unique case is reported where a 29-year-old male with preseptal cellulitis-like symptoms was found to have a Demodex mite infestation instead of a typical infection.
- This case highlights the importance for doctors to consider Demodex mites as a possible cause of ocular issues, especially when standard treatments fail.
Biologic therapy increases Demodex density in psoriasis patients.
Int J Dermatol
September 2024
Department of Dermatology, Istanbul Medeniyet University Prof. Dr. Suleyman Yalcin City Hospital, İstanbul, Turkey.
Article Synopsis
- Psoriasis patients on biologic therapy have a significantly higher density of Demodex mites compared to those who are treatment-naive or using topical treatments.
- The study found that Demodex density was notably increased on both cheeks and overall facial regions in the biologic group, with significant statistical differences.
- Results suggest that biologic treatments may affect immune response, leading to an increase in Demodex density, warranting further investigation into how various biologic agents influence this relationship.
Unveiling the Role of Endoplasmic Reticulum Stress Pathways in Canine Demodicosis.
Parasite Immunol
April 2024
UCD School of Veterinary Medicine, University College Dublin, Dublin, 4, Ireland.
Article Synopsis
- Canine demodicosis is a common skin disease caused by an overgrowth of Demodex mites, with complex factors like T-cell exhaustion and immune responses potentially playing a role in its development.
- The study employed mass spectrometry and pathway analysis to reveal that endoplasmic reticulum (ER) stress activates signaling pathways linked to immune regulation, particularly affecting Toll-like receptors and promoting M2 macrophage development.
- Findings demonstrated that the interaction between Demodex mites and the immune system creates an immunosuppressive environment that facilitates the mites' proliferation, highlighting significant molecular changes in affected dogs.
Follicular scales, scalp and ocular involvement in patients with papulopustular rosacea: prevalence and association with Demodex mite proliferation.
Dermatol Reports
March 2024
Section of Dermatology, Department of Health Sciences, University of Genoa; IRCCS Ospedale Policlinico San Martino, Genoa, Italy.
Article Synopsis
- The study examined lesser-known symptoms of rosacea and demodicosis, such as facial follicular scales, dandruff, scalp itching, and eye issues in patients with various severities of papulopustular rosacea (PPR).
- Out of 60 patients, significant percentages showed these symptoms, with follicular scales being more common in mild to moderate cases and scalp itching most prevalent in moderate rosacea.
- The research found notable differences between Demodex-positive (D+) and Demodex-negative (D-) patients, suggesting that these symptoms may indicate more severe forms of rosacea or demodicosis, and should be actively looked for in all PPR patients.