Acellular Appendix Vermiform Mucinous Neoplasm.

Appendiceal neoplasms are usually asymptomatic or associated with mild, nonspecific symptoms. Due to the rarity of the disease and the lack of specific symptoms, this clinical entity escapes the diagnostic consideration of the gynecologist, when women come in with right iliac fossa pain. A case is presented of a 56-year-old woman with a mass in the right small pelvis, which was preoperatively diagnosed as originating from the ovary.

Understanding European patterns of deprescribing antithrombotic medication during end-of-life care in patients with cancer.

Background: Even though antithrombotic therapy (ATT) probably has little or even negative effect on the well-being of patients with cancer near the end of life, it is often continued until death, possibly leading to excess bleeding complications, increased disease burden, reduced quality of life and higher healthcare costs.

Aim: To explore and describe European practice patterns and perspectives of healthcare professionals from different disciplines and specialties on ATT in the end-of-life care (EOLC) of patients with cancer.

Methods: We performed a two-week international cross-sectional survey study using flash-mob research methodology.

Telehealth memory clinics in primary healthcare: real-world experiences from low-resource settings in Greece.

Background: The role of primary healthcare is pivotal in the management of the surge of dementia prevalence particularly in low-resource areas. In this study, two telehealth-based memory clinics in primary healthcare operating within the frames of the INTegRated InterveNtion of pSychogerIatric Care (INTRINSIC) are presented.

Methods: The first clinic, which is led by a general practitioner, operates at a primary healthcare center in a semi-mountainous area and closely collaborates with the geriatric psychiatry outpatient clinic of the Patras University General Hospital via a telehealth medicine platform.

A super-giant basal cell carcinoma of the scalp.

Basal cell carcinoma is a malignant skin cancer, originating from basal cells. However, it is regarded more benign than other skin cancers, in the majority of the cases. If left untreated, it can lead to various complications, degradation of quality of life and even mortality to the patient.

Εosinophilic Chronic Obstructive Pulmonary Disease. What Do We Know So Far?

The latest advances in asthma treatment have highlighted the significance of eosinophilia and the possible role of some pro-eosinophilic mediators, like interleukins (IL) IL-5, IL-4/IL-13, and IL-33 in the disease's pathogenesis. Considering that a subgroup of patients with chronic obstructive pulmonary disease (COPD) may have blood eosinophilia akin to that seen in asthma, numerous studies in the last decade have suggested that eosinophilic COPD is a separate entity. While the exact role of blood eosinophils in the pathophysiology of COPD remains unclear, eosinophilia seems to increase the effectiveness of corticosteroid therapy.

The Molecular Determinants of Erythrocyte Removal Impact the Development of Metabolic Dysfunction-Associated Steatohepatitis.

Metabolic dysfunction-associated steatohepatitis (MASH) is a major cause of a worldwide clinical and financial burden. Despite the tremendous efforts for untangling the molecular mechanisms, there is still a need for defining specific therapeutic targets. In this editorial, the author will focus on the role of erythrocyte death and hepatic erythrophagocytosis in MASH.

Long-Term Survival After Curative Resection of a Primary Clear Cell Carcinoma of the Pancreas: A Report of a Case.

Clear cell pancreatic carcinoma, as a primary lesion, represents a rare malignant entity with very few references. As for the incidence, the clinical characteristics and the prognosis are still to be defined. Here, we present the case of a 73-year-old female who presented with epigastric pain radiating to the back, anorexia, and dyspepsia.

Prevalence of SARS-COV-2 infection and outcomes in Greek sarcoidosis patients.

Background And Aim: There is limited data on the prevalence of SARS-COV-2 in sarcoidosis patients and the underlying parameters linked to severity. We aimed to conduct a national multicenter study to explore the prevalence of SARS-COV-2 in sarcoidosis patients and investigate its impact on hospitalization and infection rates, describe the characteristics of the infected population and assess the role of these characteristics in determining the likelihood of infection or hospitalization.

Methods: We recruited all the adult sarcoidosis patients with who were examined across eight Greek Health Interstitial Lung Disease Referral Centers from the beginning of the pandemic until August 1, 2022.

The role of stem cells in the management of neonatal posthemorrhagic hydrocephalus.

Purpose: Neonatal intraventricular hemorrhage (IVH) is a common complication of prematurity as it affects 12.4% of preterm infants weighing under 1500 g. Posthemorrhagic hydrocephalus (PHH) is an important complication of neonatal IVH and can have serious long-term consequences such as cognitive impairment and cerebral palsy.

Intestinal Obstruction Due to Ingested Olive Pits.

Intestinal obstruction after ingestion of foreign bodies is a rare condition. A wide variety of ingested foreign bodies has been reported as a cause of mechanical small bowel obstruction, with ingested fruit pits being rarely reported as causes of intestinal obstruction. Here, we report the case of a 70-year-old female diagnosed with intestinal obstruction due to swallowed olive pits tightly impacted in the distal ileum.

Short Root Anomaly and Transverse Hemimelia: A Rare Case Presentation.

A case of Short Root Anomaly (SRA), hypodontia and taurodontism with the associated finding of transverse hemimelia, is presented. Although there is no documented evidence of a link between SRA and hemimelia, the shared genetic, environmental and metabolic factors suggest the possibility of a common underlying mechanism.

The mediating role of processing speed on the relationship between executive functions and social cognition in relapsing-remitting multiple sclerosis patients.

This study examined the mediating role of processing speed between executive functions and social cognition in 67 relapsing-remitting multiple sclerosis (RRMS) patients. Executive functions were assessed using the Trail Making Test-Part B (TMT-B) and the Stroop Neuropsychological Screening Test (SNST); social cognition with the Reading the Mind in the Eyes Test (RMET); and processing speed with the Symbol Digit Modalities Test (SDMT). Mediated effects were explored using a series of regression analyses and were further confirmed through bootstrapping procedures.

Anakinra efficacy in COVID-19 pneumonia guided by soluble urokinase plasminogen activator receptor: Association with the inflammatory burden of the host.

Background: Anakinra was approved by the European Medicines Agency and received Emergency Use Authorization by the United States Food and Drug Administration for patients with COVID-19 pneumonia at risk for severe respiratory failure (SRF) with blood levels of soluble urokinase plasminogen activator receptor (suPAR) ≥ 6 ng/mL. We report the final results of the phase II open-label single-arm SAVE trial in a large population.

Methods: Patients with COVID-19 pneumonia and suPAR levels ≥ 6 ng/mL received subcutaneous anakinra 100 mg once daily for 10 days.

A case of intrathoracic extramedullary hematopoiesis-associated pleural effusion in a beta-thalassemia intermedia patient and a short literature review.

Extramedullary hematopoiesis is a phenomenon that occurs in conditions of ineffective bone marrow function. In the context of thalassemias, extramedullary hematopoiesis is more frequently observed in beta-thalassemia intermedia patients, with thoracic paravertebral extramedullary hematopoiesis being relatively common. However, extramedullary hematopoiesis-related pleural effusion is a rare occurrence.

Antioxidant and anti-inflammatory properties of water kefir microbiota and its bioactive metabolites for health promoting bio-functional products and applications.

Inflammation and oxidative stress are implicated in several chronic disorders, while healthy foods and especially fermented beverages and those containing probiotics can provide anti-inflammatory and antioxidant protection against such manifestations and the associated disorders. Water kefir is such a beverage that is rich in both probiotic microbiota and anti-inflammatory bioactives, with an increasing demand as an alternative to a fermented product based on non-dairy matrix with potential health properties. Within this study, the health-promoting properties of the most representative species and strains of microorganisms present in water kefir grains, as well as the health benefits attributed to the bioactive metabolites produced by each individual strain in a series of their cultures, were thoroughly reviewed.

Tissue Expression and Plasma Soluble PD-L1 Levels in Patients With Endometrial Cancer.

Background/aim: The prognostic role of tissue PD-L1 expression in endometrial cancer (EC) remains controversial. Moreover, its value in guiding anti-PD1/PD-L1 immunotherapy is questionable. The eventual role of soluble PD-L1 (sPD-L1), released by cancer tissue and circulating immune cells, is largely unexplored.

Protection conferred by booster vaccine doses in hospitalized patients with COVID-19 during the SARS-CoV-2 Omicron BA.2 and BA.5 epidemics from 2022 to 2023 in Greece.

Background: To estimate the protection that coronavirus disease 2019 (COVID-19) vaccine doses conferred to hospitalized patients with COVID-19 against adverse outcomes and longer length of stay during the Omicron BA.2 and BA.5 subvariant epidemics in Greece.

Mental health professionals' beliefs and attitudes towards compulsory admission in Athens: a token of social stigma or good faith in psychiatry?-a cross-sectional study.

Background: Mental health professionals' (MHPs) attitudes towards involuntary admissions have not received adequate attention in efforts to curb their rates. Thus, the present study set out to (i) explore MHP attitudes regarding involuntary hospitalisation, (ii) describe their perceived dangerousness of people with severe mental illness (SMI) and their trust in psychiatry, (iii) identify the predictors of attitudes towards compulsory admissions and (iv) gauge the contribution of perceived dangerousness versus trust in psychiatry to explaining them.

Methods: A random sample of 300 mental health professionals working in public mental health services located in the Northern part of Athens and in the two psychiatric hospitals of Attica participated in the study.

Analyzing LinkedIn data to explore the relationships between sustainable development goals, circular economy, and electoral dynamics.

In 2015, all United Nations Member States adopted 17 Sustainable Development Goals (SDGs) for the 2030 agenda. Addressing the issue of employing alternative data sources for exploring aspects of utilizing said goals, this paper explores the Circular Economy dimension within the SDG12 score, focusing on responsible production and consumption and the broader SDG index. Data from LinkedIn are collected, examining profiles, companies, job postings, and services using the keywords 'Sustainable Development Goals' and 'Circular Economy'.

Boys vs men differences in muscular fatigue, muscle and cerebral oxygenation during maximal effort isometric contractions: the effect of muscle blood flow restriction.

Purpose: To examine whether the children's superiority, over adults, to resist fatigue during repeated maximal-efforts depends on their often-cited oxidative advantage, attributed to greater muscle blood flow and O-delivery. We also investigated the mechanisms underlying child-adult differences in muscle-oxygenation (due to O-supply or O-utilization) and examined if there are age-differences in cerebral-oxygenation response (a brain-activation index).

Methods: Eleven men (23.

Earth-Based Transmitters Trigger Precipitation of Inner Radiation Belt Electrons: Unveiling Observations and Modeling Results.

Human activity influence Earth's environment, including the space environment hundreds to thousands of kilometers above the Earth. One direct evidence is that the 19.8 kHz electromagnetic signals launched by the North West Cape (NWC) transmitter station in Australia produce a wisp-like energy distribution of precipitating energetic electrons in Earth's inner radiation belt, observed by many Low Earth Orbiting satellites.

The Effects of Antioxidant Supplementation on Soccer Performance and Recovery: A Critical Review of the Available Evidence.

Soccer is linked to an acute inflammatory response and the release of reactive oxygen species (ROS). Antioxidant supplements have shown promising effects in reducing muscle damage and oxidative stress and enhancing the recovery process after eccentric exercise. This critical review highlights the influence of antioxidant supplements on performance and recovery following soccer-related activity, training, or competition.