Correction: Soliman et al. Evaluating Antimicrobial Activity and Wound Healing Effect of Rod-Shaped Nanoparticles. 2022, , 2637.

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Correction: Saber et al. BD-AcAc2 Mitigates Chronic Colitis in Rats: A Promising Multi-Pronged Approach Modulating Inflammasome Activity, Autophagy, and Pyroptosis. 2023, , 953.

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Therapeutic Potential of Clove Oil in Mitigating Cadmium-Induced Hepatorenal Toxicity Through Antioxidant, Anti-Inflammatory, and Antiapoptotic Mechanisms.

Unlabelled: Hazardous heavy metals, particularly cadmium (Cd), are widely distributed in the environment and cause oxidative stress in various animal and human organs. Clove oil (CLO), a common aromatic spice, has been used as a traditional medication as it has potent anti-inflammatory, antioxidant, and hepatoprotective properties.

Background/objectives: This study aimed to investigate the antioxidant, antiapoptotic, and anti-inflammatory effects of clove oil (CLO) against hepatorenal toxicity induced by cadmium (Cd).

Localized Drug Delivery in Different Gastrointestinal Cancers: Navigating Challenges and Advancing Nanotechnological Solutions.

Different types of cancers affect the gastrointestinal tract (GIT), starting from the oral cavity and extending to the colon. In general, most of the current research focuses on the systemic delivery of the therapeutic agents, which leads to undesired side effects and a limited enhancement in the therapeutic outcomes. As a result, localized delivery within gastrointestinal (GI) cancers is favorable in overcoming these limitations.

Enhancing heart disease classification based on greylag goose optimization algorithm and long short-term memory.

Heart disease is a category of various conditions that affect the heart, which includes multiple diseases that influence its structure and operation. Such conditions may consist of coronary artery disease, which is characterized by the narrowing or clotting of the arteries that supply blood to the heart muscle, with the resulting threat of heart attacks. Heart rhythm disorders (arrhythmias), heart valve problems, congenital heart defects present at birth, and heart muscle disorders (cardiomyopathies) are other types of heart disease.

Activation of SIRT1 by SRT1720 alleviates dyslipidemia, improves insulin sensitivity and exhibits liver-protective effects in diabetic rats on a high-fat diet: New insights into the SIRT1/Nrf2/NFκB signaling pathway.

Insulin resistance and diabetes are associated with non-alcoholic fatty liver disease (NAFLD) and non-alcoholic steatohepatitis (NASH) conditions, which are distinguished by metabolic dysfunction, oxidative stress and inflammation. Sirtuin 1 (SIRT1), a NAD-dependent deacetylase, is fundamental in regulating metabolic pathways, reducing inflammation, and improving antioxidant defenses. This is the first study to investigate the effects of SRT1720, a SIRT1 activator, in diabetic rats on a high-fat diet.

Empagliflozin Mitigates PTZ-Induced Seizures in Rats: Modulating Npas4 and CREB-BDNF Signaling Pathway.

Empagliflozin (EMPA) is one of the sodium/glucose cotransporter 2 (SGLT2) inhibitors that has been recently approved for the treatment of diabetes mellitus type II. Recently, EMPA has shown protective effects in different neurological disorders, besides its antidiabetic activity. Kindling is a relevant model to study epilepsy and neuroplasticity.

Deep Learning-Based Spectrum Sensing for Cognitive Radio Applications.

In order for cognitive radios to identify and take advantage of unused frequency bands, spectrum sensing is essential. Conventional techniques for spectrum sensing rely on extracting features from received signals at specific locations. However, convolutional neural networks (CNNs) and recurrent neural networks (RNNs) have recently demonstrated promise in improving the precision and efficacy of spectrum sensing.

Investigating the Antibacterial, Antioxidant, and Anti-Inflammatory Properties of a Lycopene Selenium Nano-Formulation: An In Vitro and In Vivo Study.

Background: The potent antioxidant lycopene has attracted a large amount of research attention given its potential health benefits. We aimed to assess the antimicrobial, anti-inflammatory, and antioxidant properties of lycopene (Lyc), selenium nanoparticles (Se-NPs), and lycopene selenium nanoparticles (Lyc-Se-NPs).

Methods: FTIR, polydispersity index, and zeta potential evaluations provided a complete characterization of the synthesized Lyc-Se-NPs.

Effect of Foot Insole on Planter Pressure Distribution in Patients with Neuropathic Diabetic Foot Ulcer: A Prospective, Randomized, Double-Blinded, Controlled Clinical Trial.

Patients with diabetes polyneuropathy are at a heightened risk for developing foot ulcers, often due to dynamic plantar foot pressure patterns that lead to increased pressure and shear forces in specific foot areas. This study aimed to evaluate the effects of foot insoles on peak pressure and the pressure-time integral in patients with polyneuropathy diabetic foot ulcers over a twelve-week period followed by an eight-week follow up. : This was a prospective, randomized, double-blinded, controlled clinical trial involving 60 patients aged between 50 and 65 years of both genders.

L-carnitine attenuates autophagic flux, apoptosis, and necroptosis in rats with dexamethasone-induced non-alcoholic steatohepatitis.

Background: UpToDate, no drugs have been approved to treat nonalcoholic steatohepatitis, the advanced stage of the most prevalent liver disease, non-alcoholic fatty liver disease. The present study was conducted to explore the potential influences of L-carnitine on the pathomechanisms of hepatic injury that mediate progression to non-alcoholic steatohepatitis in dexamethasone-toxified rats.

Methods: Male Wistar rats were allocated as follows: dexamethasone group, rats received dexamethasone (8 mg/kg/day, intraperitoneally) for 6 days; DEXA-LCAR300, DEXA-LCAR500, and DEXA-MET groups, rats administered L-carnitine (300 or 500 mg/kg/day, IP) or metformin (500 mg/kg/day, orally) one week prior to dexamethasone injection (8 mg/kg/day, IP) and other six days alongside dexamethasone administration.

Enhanced human activity recognition in medical emergencies using a hybrid deep CNN and bi-directional LSTM model with wearable sensors.

Human activity recognition (HAR) is one of the most important segments of technology advancement in applications of smart devices, healthcare systems & fitness. HAR uses details from wearable sensors that capture the way human beings move or engage with their surrounding. Several researchers have thus presented different ways of modeling human motion, and some have been as follows: Many researchers have presented different methods of modeling human movements.

Nanoscale Systems for Local Activation of Hypoxia-Inducible Factor-1 Alpha: A New Approach in Diabetic Wound Management.

Chronic wounds in diabetic patients experience significant clinical challenges due to compromised healing processes. Hypoxia-inducible factor-1 alpha (HIF-1α) is a critical regulator in the cellular response to hypoxia, enhancing angiogenesis and tissue restoration. Nevertheless, the cellular response to the developed chronic hypoxia within diabetes is impaired, likely due to the destabilization of HIF-1α via degradation by prolyl hydroxylase domain (PHD) enzymes.

Microbial enzymes as powerful natural anti-biofilm candidates.

Bacterial biofilms pose significant challenges, from healthcare-associated infections to biofouling in industrial systems, resulting in significant health impacts and financial losses globally. Classic antimicrobial methods often fail to eradicate sessile microbial communities within biofilms, requiring innovative approaches. This review explores the structure, formation, and role of biofilms, highlighting the critical importance of exopolysaccharides in biofilm stability and resistance mechanisms.

Effect of Tui-Na versus positional release techniques on pregnancy-related low back pain in the third-trimester: A randomized comparative trial.

Background: Researchers are prioritizing the development of an effective treatment approach for third-trimester pregnancy-related low back pain (LBP), a prevalent and costly disorder. Therefore, this study aimed to examine the effects of Tui-Na (TN) versus positional release techniques (PRT) on third trimester pregnancy-related LBP.

Methods: Fifty pregnant women in their third trimester with low back pain were randomly assigned to 1 of 2 groups for 4 weeks of prescribed treatment (TN or PRT).

A new two-parameter Rayleigh distribution: Statistical properties, actuarial measures, regression analysis, and applications.

This paper presents a novel two-parameter distribution derived from the Rayleigh distribution, thoroughly investigating its essential mathematical properties. We employ estimation techniques to determine the proposed distribution's estimated parameters. Through extensive simulation studies, we analyze and evaluate the asymptotic behavior of the model estimators.

A case study for Kuwait mortality during the consequent waves of COVID-19.

The World Health Organization (WHO) announced on March 11, 2020, that COVID-19 could be considered a pandemic. This epidemic has become a huge issue for academics, doctors, healthcare providers, epidemiologists, and decision-makers alike. Motivated by studying natural phenomena, we concentrated on making a statistical model capable of fitting natural pandemics into the whole world.

Molecular docking and / studies of a novel thiadiazole Schiff base as a hepatoprotective drug against angiogenesis induced by breast cancer.

Two new thiadiazole imidazolium salicylidene Schiff bases (TISSBs) were successfully synthesized, and their structures were analyzed comprehensively using spectroscopic techniques. The results of the MTT assay showed that TISSB2 was the safest and most effective anti-breast cancer agent. The anti-angiogenic activity of TISSB2 was evaluated using tests in Ehrlich ascites carcinoma (EAC)-bearing Swiss albino mice.

Low-cost IoT-Based sensors dashboard for monitoring the state of health of mobile harbor cranes: Hardware and software description.

A cost-effective IoT-based real-time data acquisition and analysis hardware system was developed to enhance the performance of the mobile harbor cranes using a combination of a cost-effective quality control monitoring sensor dashboard (proximity sensors, angle position sensor, weight sensor, vibration sensor, and wind sensor), embedded microcontroller (Arduino), and embedded computer (Raspberry Pi). Hardware was operated using a specially developed novel Quality Control and Data Acquisition Multiprocessing software (QC-DAS). The QC-DAS can automatically collect and save real-time data of the sensors in a large-capacity SD card, monitor the state of health of the hardware, and transmit the real-time data of the sensors and the working state of the crane to an IoT server.

Remineralization and anti-demineralization effect of orthodontic adhesives on enamel surrounding orthodontic brackets: a systematic review of in vitro studies.

Objective: White spot lesions are initial sign of enamel caries that compromise esthetic appearance following orthodontic treatment. Thus, the systematic review was conducted to evaluate the remineralization potential of orthodontic adhesives on early-enamel lesions surrounding orthodontic bracket.

Methods: Search strategy was performed through three databases (PubMed, Web of Science, and Scopus).

Evaluation of one-shot vincristine sulfate combined with surgical excision as a new regimen for treatment of canine transmissible venereal tumor.

Objective: The purpose of this study was to investigate the effectiveness of surgical excision combined with a single shot of vincristine sulfate for treating transmissible venereal tumor (TVT) in dogs.

Materials And Methods: Fifty-two dogs were divided randomly into two groups ( 26). Dogs in Group I were treated surgically by debulking the tumorous mass, whereas dogs in Group II were subjected to a combination of surgery and a single injection of vincristine sulfate.

Realizing high-performance four active plasmonic filters using a single structure.

This research aims to contribute significantly to the field of plasmonic filtering technology within modern optical communication systems. By focusing on the development of a high-performance, more compact, and efficient design, this study explores the potential of hybrid plasmonic filters to revolutionize optical filtering applications. The approach leverages an innovative active material with electrically tunable permittivity, allowing for dynamic control over the filter's optical properties.

Hematological and iron status in aerobic vs. anaerobic female athletes: an observational study.

Introduction: Physical training induces iron status impairment in athletic females in the short term and over prolonged periods. Nevertheless, the existing literature lacks a comprehensive evaluation of the differential impacts of aerobic vs. anaerobic training on hematological indices and iron status among adolescent female athletes.