3 results match your criteria: "Dell Medical School-UT Health Austin[Affiliation]"
The use of free DNA for fetal RHD genotyping in the Rh negative pregnant patient-the time has come.
Am J Obstet Gynecol
August 2024
Department of Women's Health, Dell Medical School - UT Health Austin and the Comprehensive Fetal Center Dell Children's Medical Center, Austin, TX. Electronic address:
Article Synopsis
- Several European countries successfully integrated this method into their routine prenatal care, while it has recently been adopted by two U.S. companies using next-gen sequencing technology.
- With a current shortage of RhoGAM, there’s a push to use these reliable DNA assays in the U.S. to optimize the use of Rhesus immune globulin for RhD-negative pregnant women.
Chorionic Villous Testing Versus Amniocentesis After Abnormal Noninvasive Prenatal Testing.
Clin Obstet Gynecol
September 2023
Department of Women's Health, Dell Medical School-UT Health Austin, Austin, Texas.
In the setting of a normal first-trimester ultrasound, an amniocentesis may be a better option than chorionic villous sampling for invasive diagnostic testing after a cell-free DNA high risk for trisomy 13, given the high rates of confined placental mosaicism. In unaffected fetuses, other evaluations should be considered depending on the cell-free DNA results, including maternal karyotyping for monosomy X, uniparental disomy testing for chromosomes with imprinted genes, serial growth scans for trisomy 16, and a workup for maternal malignancy for multiple aneuploidies or autosomal monosomy.
View Article and Find Full Text PDFCongenital myotonic dystrophy: An overlooked diagnosis not amenable to detection by sequencing.
Prenat Diagn
February 2022
Department of Women's Health, Dell Medical School - UT Health Austin, Austin, Texas, USA.
Objective: To increase the clinical awareness of the need for genetic evaluation for congenital myotonic dystrophy (CDM1) in cases of fetal akinesia sequence and idiopathic polyhydramnios.
Methods: Retrospective case review.
Results: A 27 y.