A Comparison of Adverse Short-Term Outcomes After Forefoot Amputation Based on Patient Height.

Background: The objective of this investigation was to evaluate adverse short-term outcomes after partial forefoot amputation with a specific comparison performed based on patient height.

Methods: The American College of Surgeons National Surgical Quality Improvement Program database was analyzed to select patients with a 28805 Current Procedural Terminology code (amputation, foot; transmetatarsal) who underwent the procedure with "all layers of incision (deep and superficial) fully closed." This resulted in 11 patients with a height of 60 inches or less, 202 with a height greater than 60 inches and less than 72 inches, and 55 with a height of 72 inches or greater.

Survey of current practices from an international task force for gynecological stereotactic ablative radiotherapy.

Background: Stereotactic Ablative Radiotherapy (SABR) is an effective treatment that improves local control for many tumours. However, the role of SABR in gynecological cancers (GYN) has not been well-established. We hypothesize that there exists considerable variation in GYN-SABR practice and technique.

Perceived Concerns of Patients at Risk for Lower Extremity Amputation.

Unlabelled: Despite a good understanding of risk factors for amputation and the development of multidisciplinary amputation prevention teams, thousands of lower limb amputations are performed on a daily basis. These amputations are often transformative events in the lives of patients with functional, psychological, social, and economic implications.

Objective: The objective of this investigation is to qualitatively and quantitatively explore the perceived concerns of patients with chronic wounds at risk for lower extremity amputation.

The Comparison of Stereotactic Body Radiation Therapy and Intensity-Modulated Radiation Therapy for Prostate Cancer by NCCN Risk Groups.

Objectives: The primary objective of this study is to compare freedom from biochemical failure (FFBF) between stereotactic body radiation therapy (SBRT) and intensity-modulated radiation therapy (IMRT) for patients with organ confined prostate cancer treated between 2007 through 2012 utilizing the 2015 National Comprehensive Cancer Network (NCCN) risk stratification guidelines. A secondary objective is to compare our updated toxicity at last follow-up compared with pretreatment with respect to bowel, bladder, sexual functioning, and need for invasive procedures between the two groups.

Methods: We retrospectively reviewed 270 consecutive men treated with either SBRT (n = 150) or IMRT (n = 120) at a community hospital with two distinct radiation departments and referral patterns.

Propensity score matched comparison of SBRT versus IMRT for the treatment of localized prostate cancer.

Objective: Stereotactic body radiation therapy (SBRT) is an attractive option for prostate cancer due to its short treatment duration and cost. In this report, we compare the efficacy and toxicity outcomes of prostate cancer patients treated with SBRT to those who received intensity-modulated radiation therapy (IMRT).

Methods: Two hundred sixty-three patients with localized prostate adenocarcinoma were included, ranging from clinically very low- to high-risk groups.

Swimming-Induced Pulmonary Edema: Pathophysiology and Risk Reduction With Sildenafil.

Background: Swimming-induced pulmonary edema (SIPE) occurs during swimming or scuba diving, often in young individuals with no predisposing conditions, and its pathophysiology is poorly understood. This study tested the hypothesis that pulmonary artery and pulmonary artery wedge pressures are higher in SIPE-susceptible individuals during submerged exercise than in the general population and are reduced by sildenafil.

Methods And Results: Ten study subjects with a history of SIPE (mean age, 41.

Febrile Exanthem with Hyperferritinemia.

Diagnosis of an adult with acute generalized exanthem coupled with spiking fevers, arthralgias, and myalgias requires careful consideration. History and physical examination are basic necessities, while laboratory studies can be valuable adjuncts. The authors present a case of adult onset Still's disease, discuss the differential diagnoses, and highlight the utility of high serum ferritin in identifying this febrile exanthem.

SBRT: An Opportunity to Improve Quality of Life for Oligometastatic Prostate Cancer.

Objective: Oligometastatic prostate cancer is a limited metastatic disease state in which potential long-term control is still possible with the use of targeted therapies such as surgery or stereotactic body radiation therapy (SBRT). SBRT may as well potentially prolong the time before the initiation of androgen deprivation therapy (ADT) and docetaxel chemotherapy for oligometastatic prostate cancer. The goal of this study is to outline prognostic factors associated with improved outcome with SBRT for metastatic prostate cancer and to quantify the effect of prior systemic treatments such as ADT and docetaxel on survival after SBRT.

Stereotactic body radiotherapy for re-irradiation of lung cancer recurrence with lower biological effective doses.

Objective: Few studies have evaluated re-irradiation of lung cancer recurrences with stereotactic body radiotherapy (SBRT). This study evaluates outcomes with SBRT re-irradiation for recurrent lung cancer.

Methods: Two hundred and seventy-eight patients treated with SBRT for lung cancer were retrospectively reviewed.

SBRT for the Primary Treatment of Localized Prostate Cancer: The Effect of Gleason Score, Dose and Heterogeneity of Intermediate Risk on Outcome Utilizing 2.2014 NCCN Risk Stratification Guidelines.

Purpose: To report an update of our previous experience using stereotactic body radiation therapy (SBRT) for the primary treatment of prostate cancer, risk stratified by the updated National Comprehensive Cancer Network (NCCN) version 2.2014, reporting efficacy and toxicity in a community hospital setting.

Methods: From 2007 to 2012, 142 localized prostate cancer patients were treated with SBRT using CyberKnife.

Understanding the US medical school requirements and medical students' attitudes about radiology rotations.

Rationale And Objectives: To learn what percentage of US medical schools require their students to complete rotations in radiology during the clinical years. A secondary goal was to survey students' opinions about radiology rotations.

Materials And Methods: Data were collected from 159 US medical schools from the Association of American Medical Colleges (AAMC) for allopathic medical schools, the American Association of Colleges of Osteopathic Medicine (AACOM) for osteopathic medical schools, and by e-mailing curriculum directors at US medical schools with a survey.

Focal seizure propagation in the intracranial EEG.

Introduction: intracranial EEG offers a unique opportunity to study epileptic seizures in humans. Seizure propagation has not been extensively studied. We aimed to compare the propagation of focal seizures with onset in different brain regions.

Which clinical/pathologic factors matter in the era of chemoradiation as treatment for locally advanced cervical carcinoma? Analysis of two Gynecologic Oncology Group (GOG) trials.

Purpose: To explore clinical/pathologic factors associated with prognosis of patients with locally advanced cervical carcinoma treated with weekly cisplatin and pelvic radiation.

Methods: We retrospectively reviewed data from 335 women who received weekly cisplatin and radiation while participating in similar arms of two GOG studies (protocols 120 and 165). Progression-free survival (PFS) and overall survival (OS) were evaluated for associations between clinical/pathologic factors and prognosis.

Randomized comparison of weekly cisplatin or protracted venous infusion of fluorouracil in combination with pelvic radiation in advanced cervix cancer: a gynecologic oncology group study.

Purpose: Concurrent chemoradiotherapy is the standard of care for locally advanced cervix cancer; the optimal chemotherapy regimen is not yet defined. This trial was designed to compare the outcome of protracted venous infusion (PVI) fluorouracil (FU) with standard weekly cisplatin and concurrent radiation therapy (RT).

Patients And Methods: Patients with stage IIB, IIIB, and IVA cervical cancer with clinically negative aortic nodes were eligible.

Preceptors' perceptions of a competency-based orientation.

The purpose of this study was to describe preceptors' perceptions of a competency-based orientation. Results of a 26-item questionnaire that was distributed to all preceptors indicated the majority of preceptors agreed that 1. the identified core competencies were role- and unit-specific, and 2.

Nurses' attitudes and practices regarding voluntary continuing education.

This article describes registered nurses' attitudes and practices regarding voluntary continuing education and identifies the factors that influence their decision to participate or not participate. This information is essential for nurse educators in order to meet the education needs of staff.

The efficacy and safety of once-daily Kytril (granisetron hydrochloride) tablets in the prophylaxis of nausea and emesis following fractionated upper abdominal radiotherapy.

This multicenter, randomized, double-blind study compared the efficacy and safety of once-daily oral granisetron 2 mg (n = 134) and placebo (n = 126) as prophylaxis for nausea and emesis in patients receiving upper abdominal fractionated radiotherapy. Patients were scheduled to receive 10-30 fractions of radiotherapy; granisetron (two 1-mg tablets) or placebo was administered 1 hr before radiotherapy on each scheduled treatment day. Treatment comparisons were made at 24 hr and at 10 and 20 fractions.

Optimizing radiation treatment for cervical cancer.

The technical and radiobiological improvements in the science of radiotherapy, coupled with the use of cisplatin-containing regimens concurrent with radiation therapy, have improved dramatically the cure rate and quality of Life for cervical cancer survivors. Further research is necessary to understand the complex dose distribution of external beam and intracavitary radiation and their relationship to tumor control and complications. With the use of CT-compatible applicators for intracavitary radiation, CT simulation and three-dimensional treatment planning for EBRT, the radiation oncology community should meet this challenge.

Fine needle aspiration diagnosis of lymphangiomyomatosis. A case report.

Background: Lymphangiomyomatosis is a rare disease of females, usually of reproductive age. There is a proliferation of lymphatic smooth muscle in mediastinal, retroperitoneal and often pulmonary lymphatics and lymph nodes.

Case: A 45-year-old female presented with a right pleural effusion and increasing retroperitoneal adenopathy with palpable left inguinal adenopathy.

20 Years of Progress in Radiation Oncology: Prostate Cancer.

Carcinoma of the cervix remains of special interest to the Patterns of Care Study (PCS) because of the prominent role that radiotherapy plays in the definitive management of all stages and extents of disease. Five PCS surveys have been conducted for squamous cell cancer of the uterine cervix beginning in 1973 and repeated thereafter at 5-year intervals. The records of over 2,700 women have been reviewed for these surveys.

Radiotherapy for the treatment of locally recurrent cervical cancer.

Following radical hysterectomy for stage I-IIA cervical carcinoma, 10%-15% of women will have a recurrence. Sixty percent of these recurrences will be located in the pelvis alone. The treatment of a localized pelvic recurrence depends on a number of factors, but primarily the history of previous radiation therapy (RT) to the pelvis and the location of the recurrence.

Metastatic liposarcoma of the brain with response to chemotherapy: case report.

Metastatic liposarcomas to the brain are rare. The authors describe a patient with a 20-year history of liposarcoma originating in the thigh and metastatic to the brain 18 years later. The brain metastasis was removed by surgery.