397,871 results match your criteria: "Del; Sidney Kimmel Medical College of Thomas Jefferson University SA Deutsch[Affiliation]"

Unlabelled: No consensus has been reached about how cognitive performance evolves in patients receiving hemodialysis (HD).

Aim: to analyze the cognitive performance of patients with end-stage chronic kidney disease (CKD) undergoing conservative medical management or HD.

Methods: We conducted a cross-sectional study.

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Hereditary tyrosinemia type 1 (HT-1) is an inborn error of metabolism caused by a defect in tyrosine (tyr) degradation. This defect results in the accumulation of succinylacetone (SA), causing liver failure with a high risk of hepatocarcinoma and kidney injury, leading in turn to Fanconi syndrome with urine loss of phosphate and secondary hypophosphatemic rickets (HR). HT-1 diagnosis is usually made in infants with acute or chronic liver failure or by neonatal screening programs.

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[Breast Cancer in Male Patients of the Aconcagua Valley During the Period 2013-2018].

Rev Med Chil

September 2024

Escuela de Medicina, Facultad de Medicina, Universidad de Valparaíso, San Felipe, Chile.

Unlabelled: Breast cancer in men is a rare disease, accounting for around 1% of all cancers in males. Diagnosis often occurs in advanced stages due to low awareness of this disease in males.

Aim: To evaluate the clinical, epidemiological, and histopathological characteristics of breast cancer in men in the Aconcagua Valley and its relationship with patient survival.

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Unlabelled: People with type 2 diabetes mellitus (DM2) experience difficulties in self-management. One of the variables involved is the low level of health literacy (HL) which corresponds to the degree to which people access, understand, evaluate and use information to engage with health demands in different contexts, in order to promote and maintain good health.

Hypothesis: People diagnosed with diabetes mellitus who participate in an intervention to increase their level of health literacy improve their metabolic compensation measured in HBA1c.

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Unlabelled: Acute myeloid leukemia (AML) is the most frequent type of leukemia in adults and has a high mortality burden. Patients over 60 years of age infrequently receive high-intensity chemotherapy.

Aim: To describe the clinical characteristics and evaluate the survival in patients with AML, focusing on patients over 60 years.

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Secondhand smoke affects nearly 40% of children worldwide, leading to serious health and behavioral problems. Being neurotoxic, it poses potential risks for child health and learning. In Cuba, there is limited research on the association of secondhand smoke with children's brain health, especially in vulnerable populations like young children at home.

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New Plastitar Record for the Mediterranean Sea: Characterization of Plastics and Tar from the Salento Peninsula (Ionian Sea).

Toxics

December 2024

Department of Biological and Environmental Science and Technology (Di.S.Te.B.A.), University of Salento, Campus Ecotekne, Via Prov. Lecce-Monteroni, 73100 Lecce, Italy.

The various forms of anthropogenic pollution are regarded as a serious threat to marine coastal areas. The overproduction and mismanagement of petroleum derivatives, such as tar and plastics, have resulted in a significant correlation between these two pollutants. The aggregation of tar, microplastics (MPs), and natural materials can create plastitar blocks, which are common in coastal areas.

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The study aimed to identify expert opinions and obtain recommendations on the management of post-stroke hemiplegic shoulder pain (HSP) and treatment with botulinum toxin A (BoNT-A). A multicenter Delphi study was conducted using an online survey designed by a committee of experts with at least 10 years of experience in post-stroke HSP management with BoNT-A in Spain. Forty-seven panelists (specialists with at least 5 years of experience in post-stroke HSP management with BoNT-A) rated their level of agreement in two rounds based on acceptance by ≥66.

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The discovery of novel cytotoxic drugs is of paramount importance in contemporary medical research, particularly in the search for treatments with fewer side effects and higher specificity. Antimicrobial peptides are an interesting class of molecules for this endeavor. In this context, the LyeTx III, a new peptide extracted from the venom of the spider, stands out.

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Characterization, Quantification, and Molecular Identification of Co-Infection of Canine Parvovirus (CPV-2) Variants in Dogs Affected by Gastroenteritis in Ecuador During 2022-2023.

Vet Sci

January 2025

Facultad de Ciencias de La Salud, Carrera de Medicina Veterinaria, Universidad de Las Américas (UDLA), Antigua Vía a Nayón S/N, Quito EC 170124, Ecuador.

Canine parvovirus (CPV-2) is a highly contagious virus in canines, and it is mostly spread by touching infected feces. Dogs of all ages can catch it, but puppies are more likely to suffer from it. Severe signs include vomiting, diarrhea with blood, feeling tired, and not drinking enough water.

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The kidney length (KL) to aortic diameter (AoD) ratio (KL/AoD) has been proposed as an ultrasonographic objective method to assess renal dimensions. However, its wide range of normal values limits sensitivity. Of note, its clinical utility in detecting renal disease has not been investigated.

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Background/objectives: Influenza vaccination is the main method for preventing influenza. The objectives of this study are to evaluate the opinions of families on influenza vaccination and to determine the acceptance of influenza vaccination as a routine vaccine in children under 5 years of age.

Methods: The method used was a descriptive cross-sectional study based on an ad-hoc survey.

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In this work, a series of BaMnCuO samples (x: 1, 0.9, 0.8, and 0.

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This study provides a comprehensive structural, chemical, and optical characterization of CZTS thin films deposited on flexible Kapton substrates via the Successive Ionic Layer Adsorption and Reaction (SILAR) method. The investigation explored the effects of varying deposition cycles (40, 60, 70, and 80) and annealing treatments on the films. An X-ray diffraction (XRD) analysis demonstrated enhanced crystallinity and phase purity, particularly in films deposited with 70 cycles.

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Designing and Fabrication of Nano-Hydroxyapatite and Curcumin-Loaded Chitosan/PVA Nanofibrous Mats for Potential Use as Wound Dressing Biomaterials.

Nanomaterials (Basel)

January 2025

Consiglio Nazionale delle Ricerche (CNR), Istituto per la Sintesi Organica e Fotoreattività (ISOF), Via Piero Gobetti, 101, 40129 Bologna, Italy.

Chitosan/polyvinyl alcohol nanofibrous mats loaded with nano-hydroxyapatite and/or curcumin are successfully fabricated by the electrospinning method for the first time. Nano-hydroxyapatite is prepared by the co-precipitation method. The XRD pattern of calcined powder at 700 °C for 2 h reveals the presence of hydroxyapatite as a sole phase.

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: Being a healthcare professional often involves exposure to complex situations that can contribute to the development of psychological problems. Evidence suggests that both mental and physical health are crucial for the well-being of these professionals, which in turn influences the quality of care they provide to patients. The main aim of this study was to examine the association between adaptive and maladaptive forms of humor and psychopathological disorders among healthcare workers.

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Optimizing Muscle Performance in Young Soccer Players: Exploring the Impact of Resisted Sprint Training and Its Relationship with Distance Covered.

Sports (Basel)

January 2025

Escuela de Ciencias de la Actividad Física, El Deporte y la Salud, Facultad de Ciencias Médicas, Universidad de Santiago de Chile, Santiago 8370003, Chile.

Background: Speed training with resisted sprints has been shown to positively affect neuromuscular performance in soccer players. Various loads, ranging from 10% to 120% of body mass, have demonstrated performance improvements across the spectrum. However, the impact of sprint distance with optimal load on these adaptive responses has yet to be thoroughly described.

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The aim of this study was to compare the external load of each session along competitive microcycles on an elite futsal team, considering the positions and relationships of the players. The external load of 10 elite players from a First Division team in the Spanish Futsal League (age 27.5 ± 7 years, height 1.

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The widely available options of different manufacturers in dental implant systems have complicated the selection criteria process for periodontists, necessitating careful consideration of various factors when selecting suitable solutions for individual patient needs. Optimal implant selection requires careful consideration of the patient-specific factors, implant design, and surgical technique. Understanding the biomechanical behavior of implant-tissue interactions is crucial for achieving successful and long-lasting implant therapy.

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Wild or Reared? Jellyfish as a Potential Biofactory.

Mar Drugs

January 2025

Consiglio Nazionale delle Ricerche, Istituto di Scienze delle Produzioni Alimentari, (CNR-ISPA)-Lecce, Via Monteroni, 73100 Lecce, Italy.

The zooxanthellate jellyfish (Forsskål, 1775), a Lessepsian species increasingly common in the western and central Mediterranean Sea, was investigated here to assess its potential as a source of bioactive compounds from medusa specimens both collected in the wild (the harbor of Palermo, NW Sicily) and reared under laboratory-controlled conditions. A standardized extraction protocol was used to analyze the biochemical composition of the two sampled populations in terms of protein, lipid, and pigment contents, as well as for their relative concentrations of dinoflagellate symbionts. The total extracts and their fractions were also biochemically characterized and analyzed for their in vitro antioxidant activity to quantify differences in functional compounds between wild and reared jellyfish.

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One of the most important steps in preclinical drug discovery is to demonstrate the in vivo efficacy of potential leishmanicidal compounds and good characteristics at the level of parasite killing prior to initiating human clinical trials. This paper describes the use of dehydrothyrsiferol (DT), isolated from the red alga , in a pharmaceutical form supported on Sepigel, and the in vivo efficacy against a mouse model of cutaneous leishmaniasis. Studying the ultrastructural effect of DT was also carried out to verify the suspected damage at the cellular level and determine the severity of damages produced in the homeostasis of promastigotes.

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Groundbreaking Technologies and the Biocontrol of Fungal Vascular Plant Pathogens.

J Fungi (Basel)

January 2025

Department of Soil and Plant Microbiology, Estación Experimental del Zaidín, CSIC, Profesor Albareda 1, 18008 Granada, Spain.

This review delves into innovative technologies to improve the control of vascular fungal plant pathogens. It also briefly summarizes traditional biocontrol approaches to manage them, addressing their limitations and emphasizing the need to develop more sustainable and precise solutions. Powerful tools such as next-generation sequencing, meta-omics, and microbiome engineering allow for the targeted manipulation of microbial communities to enhance pathogen suppression.

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The Effect of Temperature over the Growth and Biofilm Formation of the Thermotolerant .

J Fungi (Basel)

January 2025

Departamento de Microbiología, Escuela Nacional de Ciencias Biológicas, Instituto Politécnico Nacional, Prol. Carpio y Plan de Ayala s/n Col. Casco de Santo Tomás, Alcaldia Miguel Hidalgo, Mexico City C.P. 11340, Mexico.

is a medically relevant fungus, particularly in tropical regions. Although its aflatoxin production and thermotolerance are well documented, its biofilm-forming ability has received less attention, despite being a key factor in the virulence of as an opportunistic pathogen, which can significantly impact therapeutic outcomes. To investigate the influence of temperature on the growth and biofilm formation of an isolate, we compared it on solid media with the reference strain ATCC 22546 and documented morphological changes during conidial germination.

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Evaluation of spp. System Model Against .

J Fungi (Basel)

January 2025

Instituto de Biología Funcional y Biotecnología (BIOLAB)-INBIOTEC-CONICET-CICBA, Facultad de Agronomía, Universidad Nacional del Centro de la Provincia de Buenos Aires, Av. República de Italia # 780, Azul 7300, BA, Argentina.

Cereal crops are affected by one of the most devastating diseases worldwide, known as Fusarium head blight (FHB), with being the most isolated causal pathogen. Another species associated with this disease is . This species has been considered a relatively weak pathogen compared to , but its importance has increased due to its occurrence in cereal grains worldwide.

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Older adults in the third-age group (60-79 years) maintain reading comprehension skills similar to those of younger adults, but little is known about individuals in the fourth age (80+ years). This study investigates differences in reading comprehension in a between-group design. We evaluated a sample of 150 older adults, comprising 86 third-age and 64 fourth-age participants.

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