3 results match your criteria: "Dekernes General Hospital[Affiliation]"
A study of granulysin and pentraxin 3 genetic polymorphisms and their contribution to acne susceptibility.
Arch Dermatol Res
October 2024
Dermatology and Andrology Department, Dekernes General Hospital, Dakahlia Governorate, Egypt.
Article Synopsis
- - This study investigates genetic variations in the GNLY and PTX3 genes and their link to acne in Egyptian individuals, highlighting the inflammatory nature of acne as a skin disorder.
- - The research included 180 acne patients and 180 healthy controls, using real-time PCR to analyze specific genetic polymorphisms (SNPs) related to these genes.
- - Results showed that the PTX3 rs2305619 variant is significantly associated with acne susceptibility, indicating that individuals with certain genotypes (AG + GG) are more likely to develop acne, while the GNLY rs7908 polymorphism does not show a similar association.
Concurrent genotyping and expression of NLRP3 inflammasome in pityriasis versicolor patient's skin lesions.
Arch Dermatol Res
August 2024
Medical Biochemistry and Molecular Biology Department, Faculty of medicine, Menoufia University, Shebin Elkom, Egypt.
Article Synopsis
- The study examines how the rs35829419 SNP affects serum levels of NLRP3 and its link to the skin condition Pityriasis versicolor (PV).
- It involves a case-control analysis with 50 PV patients and 44 healthy individuals, utilizing real-time PCR for genotyping and ELISA assays for NLRP3 levels.
- Results indicate higher NLRP3 levels in PV patients, a significant association of the A allele with increased disease risk, and a potential therapeutic target in the NLRP3 inflammasome for Malassezia-related skin issues.
Role of intrafamilial transmission in high prevalence of hepatitis C virus in Egypt.
Hepat Med
June 2017
Department of Medical Biochemistry.
Background: Egypt has the highest prevalence of hepatitis C virus (HCV) worldwide. Although an effective HCV treatment program has been adopted, it is estimated that the number of newly reported cases in Egypt is still high. Intrafamilial transmission may play a role in the high prevalence of HCV in Egypt.
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