3 results match your criteria: "DePaul University Center for Community Research[Affiliation]"

Joint Flexibility and Myalgic Encephalomyelitis/Chronic Fatigue Syndrome After Mononucleosis.

Clin Ther

March 2024

Northwestern University Feinberg School of Medicine, Department of Pediatrics, Chicago, Illinois, USA; Ann & Robert H Lurie Children's Hospital of Chicago, Division of Infectious Diseases, Chicago, Illinois, USA. Electronic address:

Purpose: Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a chronic disease characterized by substantial fatigue, postexertional malaise, unrefreshing sleep, and orthostatic intolerance, among other symptoms. Specific risk factors for the development of ME/CFS have not been adequately characterized. It has been suggested that ME/CFS is a connective tissue disorder and that joint hyperflexibility is a risk factor for the development of ME/CFS.

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Purpose: Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a chronic condition with a constellation of symptoms presenting as severe and profound fatigue of ≥ 6 months not relieved by rest. ME/CFS affects health-related quality of life (HRQoL), which can be measured using multi-attribute health state utility (HSU) instruments. The aims of this study were to quantify HSUs for people living with ME/CFS, and to identify an instrument that is preferentially sensitive for ME/CFS.

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Article Synopsis
  • The research aimed to evaluate a short form of the Involvement in Alcoholics Anonymous scale (IAA-SF), focusing on its factor structure, internal consistency, and predictive validity.
  • The study involved two diverse samples—one from post-treatment adults in northern Illinois and another from recovery home residents across the U.S.—utilizing various analytical methods to assess the scale's effectiveness.
  • Results indicated that the IAA-SF measures three key involvement dimensions (Principles, Social, and Spiritual) with strong reliability, and highlighted that social and global involvement could predict better chances of maintaining abstinence after two years, showcasing its usefulness in understanding 12-step program participation.
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