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SUMO-specific peptidase 3 mediates the SUMO3 modification of BECN1 to repress cell autophagy in gliomas.
Histol Histopathol
June 2024
Department of Anus and Intestine Surgery, Dayao Town Central Health Center, Liuyang, Hunan, PR China.
Objective: SUMO Specific Peptidase 3 (SENP3) is involved in the occurrence and development of various cancers. However, its effects on gliomas have been barely reported. Herein, this research was designed to probe the potential mechanisms of SENP3 mediating beclin-1(BECN1) SUMO3 modification in autophagy in gliomas.
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