3 results match your criteria: "Davis School of Medicine Davis CA.[Affiliation]"
J Am Heart Assoc
July 2022
Division of Pulmonary, Critical Care and Sleep Medicine, Lung Center University of California, Davis School of Medicine Davis CA.
Background In murine heart failure models and in humans with diabetic-related heart hypertrophy, inhibition of phosphodiesterase 5 (PDE5) by sildenafil improves cardiac outcomes. However, the mechanism by which sildenafil improves cardiac function is unclear. We have observed a relationship between PDE5 and β2 adrenergic receptor (β2AR), which is characterized here as a novel mechanistic axis by which sildenafil improves symptoms of diabetic cardiomyopathy.
View Article and Find Full Text PDFClin Liver Dis (Hoboken)
November 2016
Program for Autoimmune Liver Diseases, International Center for Digestive Health, Department of Medicine and Surgery University of Milan-Bicocca Milan Italy.