9,969 results match your criteria: "Dartmouth Hitchcock Medical Center.[Affiliation]"

Patient-Initiated Communication After Parotidectomy.

Laryngoscope

October 2024

Department of Otolaryngology Head and Neck Surgery, University of Michigan Health System, Ann Arbor, Michigan, U.S.A.

Objectives: We sought to study the incidence of patient-initiated communication after parotidectomy, identify patient and surgical factors associated with patient-initiated communication, and evaluate trends and possible areas for improvement.

Methods: A retrospective cohort study of patients who underwent parotidectomy without combined procedures from 2018 to 2022 in a single tertiary-care institution was performed. We reviewed all patient communications documented within the electronic medical record within 30 days of discharge.

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Background: Transcarotid artery revascularization (TCAR) has emerged as an alternative therapeutic modality to carotid endarterectomy (CEA) and transfemoral carotid artery stenting (TFCAS) for the management of patients with carotid artery stenosis. However, certain issues regarding the indications and contraindications of TCAR remain unanswered or unresolved. The aim of this international, expert-based Delphi consensus document was to attempt to provide some guidance on these topics.

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Article Synopsis
  • - A recent study highlights that adults who started smoking cigarettes before age 15 are at a significantly higher risk for COPD compared to those who began at 15 or older, regardless of their current smoking habits or exposure to second-hand smoke.
  • - In the analysis involving U.S. adults aged 40 and older, 13.4% reported having COPD, with prevalence rates of 29.0% for those who started smoking before 15 and 21.1% for those who started at 15 or older.
  • - The research indicates that those who began smoking early not only had a higher prevalence of COPD but also showed greater intensity in smoking behaviors, highlighting the long-term health risks associated with childhood smoking initiation.
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During the 2022-2023 mpox outbreak in the United States, the federal government distributed mpox vaccines to individual states. Significant variation in vaccine coverage was noted across states. State-level factors associated with higher vaccine coverage were Democratic political orientation, higher public health spending, higher proportion of at-risk population, and higher mpox cases.

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Background: Commercial single-use endoscopic multiband ligators, used for esophageal variceal band ligation (EVL), are prohibitively expensive. To enable greater access to EVL, we used disruptive innovation to develop a novel endoscopic multiband ligator.

Methods: We designed and tested a prototype handle 'ENDOhandle' using computer-aided design modeling and exported a cap, trigger cord and latex to form a functional banding unit.

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Purpose: The utility of machine learning, specifically large language models (LLMs), in the medical field has gained considerable attention. However, there is a scarcity of studies that focus on the application of LLMs in generating custom subspecialty radiology impressions. The primary objective of this study is to evaluate and compare the performance of multiple LLMs in generating specialized, accurate, and clinically useful radiology impressions for degenerative cervical spine MRI reports.

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  • Patients with ulcerative colitis (UC) experiencing severe flares in the hospital are a unique and high-risk group requiring specialized clinical trial designs.
  • A multi-centre consortium is developing a trial for hyperbaric oxygen therapy, addressing important factors like inclusion/exclusion criteria, disease activity measures, and tailored care pathways.
  • The study highlights the need for comprehensive outcome measures and standardized care practices while emphasizing the significance of early intervention and statistical planning in these small clinical trials.
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  • Mesenchymal neoplasms in the nasal cavity, such as angioleiomyoma (AL) and angiomyolipoma (AML), are rare tumors that involve vascular, smooth muscle, and adipocytic components, with unclear classifications as hamartomas or true neoplasms due to limited genetic research.
  • A multi-institutional retrospective study collected data on 15 nasal cavity lesions, primarily affecting older males with obstructive symptoms, and analyzed tissue samples for genetic features.
  • The study discovered that most cases had a high proportion of smooth muscle, with some showing additional components like blood vessels and fatty tissue, while all lesions were positive for smooth muscle markers, indicating their muscular origin.
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  • The study analyzed data from the New Hampshire Colonoscopy Registry to identify factors affecting colonoscopy cecal intubation rates, focusing on patient demographics and endoscopist characteristics.
  • Results indicated that women, older patients, and those with certain BMI categories (either low or high) were less likely to have complete colonoscopies, with men having a higher completion rate.
  • Endoscopist factors such as specialization in gastroenterology and higher adenoma detection rates were associated with increased likelihoods of completion, particularly impacting thin women.
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  • - The study is a secondary data analysis of an NIH-sponsored research focusing on cost-effectiveness between surgical and non-surgical treatments for Adult Symptomatic Lumbar Scoliosis (ASLS) eight years post-enrollment.
  • - Previous analyses at the five-year mark showed a cost-effectiveness ratio (ICER) of $44,033 (As-Treated) and $27,480 (Intent-to-treat), while the current eight-year data suggests that surgical treatment is more economically favorable, with an ICER of $20,569 per Quality Adjusted Life Year (QALY) gained.
  • - The conclusion highlights that operative treatment for ASLS presents a more cost-effective option compared to non-operative treatment, as indicated
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Importance: How rates of thyroid cancer diagnosis were affected by the emergence of COVID-19 variants during the 2020 to 2021 era of the pandemic has not been described.

Objective: To estimate the total number of undiagnosed cases of thyroid cancer, by histologic type, during the first 2 years of the COVID-19 pandemic (2020 and 2021) by comparing observed to expected incidence and to test for changes in size of cancer at incidence during the same period compared to prior years.

Design, Setting, And Participants: This longitudinal study analyzed trends in thyroid cancer diagnoses from 2016 to 2021 among US adults using data from the Surveillance, Epidemiology, and End Results 22 (SEER-22) program database.

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Travel burden and bypassing closest site for surgical cancer treatment for urban and rural oncology patients.

J Rural Health

October 2024

Departments of Medicine and of Community and Family Medicine, The Dartmouth Institute for Health Policy and Clinical Practice, Geisel School of Medicine at Dartmouth, and Dartmouth Cancer Center, Lebanon, New Hampshire, USA.

Article Synopsis
  • The study analyzed how travel burden for surgical cancer care is affected by rural living, geographic choices, cancer type, and patient mortality outcomes using Medicare data from 2016-2018.
  • It found that a significant percentage of cancer patients, particularly those in rural areas, chose to bypass their nearest surgical facility, leading to better survival outcomes post-surgery.
  • The research highlights that understanding why rural patients bypass facilities could help improve cancer treatment results and address disparities in cancer care access.
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Food Allergy, Nutrition, Psychology, and Health.

J Allergy Clin Immunol Pract

October 2024

Section of Allergy and Immunology, Dartmouth-Hitchcock Medical Center, Lebanon, NH; Departments of Medicine and Pediatrics, Geisel School of Medicine at Dartmouth, Hanover, NH. Electronic address:

Article Synopsis
  • - The article discusses how individuals with food allergies have limited "food freedom," leading to various challenges including cognitive, emotional, social, nutritional, and financial impacts.
  • - It suggests that avoiding certain foods can affect gut health and potentially contribute to neuroinflammatory issues, impacting mental health.
  • - The use of psychological counseling is highlighted as a helpful approach, while also noting that strict dietary restrictions might hinder overall dietary health benefits.
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Fluorescence cryo-imaging is a high-resolution optical imaging technique that produces 3-D whole-body biodistributions of fluorescent molecules within an animal specimen. To accomplish this, animal specimens are administered a fluorescent molecule or reporter and are frozen to be autonomously sectioned and imaged at a temperature of -20°C or below. Thus, to apply this technique effectively, administered fluorescent molecules should be relatively invariant to low temperature conditions for cryo-imaging and ideally the fluorescence intensity should be stable and consistent in both physiological and cryo-imaging conditions.

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  • The systematic review aimed to assess how testosterone affects uterine and ovarian health in transmasculine individuals undergoing gender-affirming surgery.
  • After analyzing 28 full-text articles, it was found that the majority of endometrial tissues were either atrophic or proliferative, with a few cases showing precancerous changes.
  • No ovarian cancers were identified, suggesting that testosterone treatment does not significantly elevate the risk of serious gynecological issues in these patients.
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Cigarette Smoke Exposure Impairs Fracture Healing in a Rat Model: Preferential Impairment of Endochondral Over Membranous Healing.

J Biomech Eng

January 2025

Department of Orthopaedics and Physical Medicine, Medical University of South Carolina, Bioengineering Building 227, 68 President Street, Charleston, SC 29425; Department of Orthopaedics, Dartmouth-Hitchcock Medical Center and Geisel School of Medicine at Dartmouth, 1 Medical Center Drive, Lebanon, NH 03756.

Article Synopsis
  • Cigarette smoking negatively impacts the healing process of fractures, specifically delaying healing and increasing the risk of nonunion.
  • The study tested how cigarette smoke affects two types of bone healing (intramembranous vs. endochondral) using rat models with femur fractures treated with different methods.
  • Results showed that fractures treated with compression plating healed faster and more completely than those treated with intramedullary nailing, particularly in smoke-exposed animals, suggesting better surgical outcomes for smokers if compression plating is used.*
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Background: Adult people with cystic fibrosis (PwCF) have a higher risk of end-stage kidney disease than the general population. The nature and mechanism of kidney disease in CF are unknown. This study quantifies urinary kidney injury markers and examines the hypothesis that neutrophil activation and lung infection are associated with early kidney injury in CF.

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  • Ossifying fibromyxoid tumor (OFMT) is a rare soft tissue tumor often found in subcutaneous tissues, characterized by bland ovoid cells and metaplastic bone.
  • The tumors typically pose diagnostic challenges when they present with unusual characteristics, necessitating the detection of specific gene fusions for accurate diagnosis.
  • This study discusses six cases of OFMT with atypical features and emphasizes the importance of molecular testing in confirming diagnoses, highlighting a case with a novel gene fusion (EPC1::SUZ12).
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Teamwork in Clinical Medicine.

J Allergy Clin Immunol Pract

December 2024

Department of Allergy and Clinical Immunology, Cleveland Clinic, Cleveland, Ohio.

Clinical teams are at the heart of healthcare value. Teamwork requires an appreciation of the unique geniuses of each team member as well as an understanding of team dynamics and larger organizational challenges. Effective teams leverage each member's unique talents within a culture of shared humility, service, and dedication.

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Background: Differential access to new technologies may contribute to racial disparities in surgical outcomes but has not been well-studied in the treatment of carotid artery stenosis. We examined race-based differences in adoption and outcomes of transcarotid artery revascularization (TCAR) among high-risk non-Hispanic (NH) Black and NH white adults undergoing carotid revascularization.

Methods: We conducted a retrospective analysis of TCAR, transfemoral carotid artery stenting (TF-CAS), and carotid endarterectomy (CEA) procedures performed for carotid artery stenosis from January 2015 to July 2023 in the Vascular Quality Initiative.

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Objective: Hospital-based labor and delivery units are closing at increasing rates in the rural US, significantly impacting maternal and newborn health. The objective of this study to determine if rurality-measured as distance from the hospital-and socioeconomic status-measured as insurance payor-impact both spontaneous and medically indicated preterm birth incidence at a single rural academic institution.

Methods: This was a retrospective cohort study using electronic medical records of patients with singleton pregnancies delivering at a single rural academic institution between 2016-2018.

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Revascularization of renal artery stenosis became less common following randomized controlled trials that failed to demonstrate benefit in low-risk patients. An 88-year-old patient with recurrent acute pulmonary edema and progressive kidney disease in the setting of high-grade renal artery stenosis, a phenotype excluded from these trials, underwent revascularization.

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