Evaluation of modified essay questions (MEQs) as an assessment tool in third-year medical students' modular summative assessment.

Aim: Whether case-based modified essay questions (MEQs) are crucial to summative assessment in medical curriculum is still debatable. The current study aimed to evaluate third-year medical students' performance in case-based MEQs and multiple-choice questions (MCQs) in summative assessment in the endocrine module.

Methods: Students' scores in mid and final module MEQs and MCQs were analyzed over four successive years from 2018/2019 to 2021/2022, where comparisons were made between students' scores in MEQs and MCQs, and between scores of students of different categories.

The Influence of Early Maladaptive Schemas on Recovery and Psychological Capital in Borderline Personality Disorder Clients: Findings From Rural Dwelling Sample.

Introduction: Early maladaptive schemas (EMSs) are among the key vulnerability factors explaining the development and persistence of symptoms in borderline personality disorder (BPD). Furthermore, it was suggested that EMSs might impact recovery-related outcomes, including psychological and recovery capital, among individuals with BPD.

Aims: To investigate the relationship among EMSs, psychological and recovery capital in individuals with BPD disorder.

Neutrophil-to-lymphocyte and platelet-to-lymphocyte ratios as mortality predictors in acute Aluminum phosphide (grain pills) poisoning: clinical insights and risk assessment.

Background: Aluminum phosphides (AlP) is a solid fumigant pesticide known for its high toxicity and mortality. Diagnosis of AlP is based on the history and clinical examination. The literature on the early prediction of adverse outcomes following AlP exposure is limited.

Assessment of Stress Distribution Around Traditional and Sleeve Fixed Partial Denture Designs: Finite Element Analysis.

Objectives:  The aim of this research is to evaluate/compare the use of traditional versus sleeve fixed partial denture (PD) designs made from different materials on supporting structures. The comparison included three- and four-unit PD cases.

Materials And Methods:  Four finite element models are used in the research.

The role of artificial intelligence literacy and innovation mindset in shaping nursing students' career and talent self-efficacy.

Background: As artificial intelligence (AI) transforms nursing education, AI literacy is becoming a critical necessity for increasing the career potential and talent of nursing students. Additionally, fostering an innovation mindset promotes adaptability, creativity and openness to new approaches, further boosting students' confidence in their careers. However, few studies have examined the impact of these competencies on nursing students' career and talent self-efficacy, underscoring the need for further investigation.

Mutagenicity and DNA damage assessment of locally produced nano-hydroxyapatite-silica-glass ionomer cement on human periodontal ligament fibroblasts using Ames and Comet assays.

Aim: This research assessed the mutagenicity and DNA damage of a novel type of nano-hydroxyapatite-silica glass ionomer cement (nano-HA-SiO-GIC) and a conventional GIC (cGIC) using Ames and Comet assays.

Methods: Cell viability was tested on human periodontal ligament fibroblasts (HPLFs) using 3.125 mg/ml, 6.

Proteomic Profiling of COVID-19 Patients Sera: Differential Expression with Varying Disease Stage and Potential Biomarkers.

: SARS-CoV-2 is one of the viruses that caused worldwide health issues. This effect is mainly due to the wide range of disease prognoses it can cause. The aim of this study is to determine protein profiles that can be used as potential biomarkers for patients' stratification, as well as potential targets for drug development.

International nursing students' culture shock and academic engagement: The moderating role of resilience.

Background: The nursing profession has experienced a growing influx of international nursing students pursuing nursing degrees in the current era. Predicting and controlling culture shock among this special group is a critical issue as it shapes their academic engagement. Building resilience capabilities among this set of students is a pivotal necessity to buffer the effect of culture shock on their academic engagement.

Navigating transition shock: The role of system thinking in enhancing nursing process competency among early career nurses.

Background: Building nursing process competency among beginner nurses is a pivotal need in contemporary, complex, fast-paced nursing practice. However, transitioning from the educational phase to practicing as a nurse can be a significant adjustment. New practitioners often experience a period of shock, which may present challenges in developing nurse competency.

Efficiency of bulk-fill versus conventional resin-based composite in class II restorations: A dental student perspective.

Purpose/objectives: The aim of the study was to evaluate the effect of two distinct light-polymerization protocols, used by dental students, on the placement time and polymerization efficiency of bulk-fill (BF) and conventional (CRC) resin-based composites (RBCs).

Methods: Thirty dental students participated in this study. Each student was asked to complete four Class II RBC restorations using two different types of RBCs (BF and CRC) paired with two distinct light-polymerization protocols: one using 1200 mW/cm irradiance (P1200) and one using 800 mW/cm irradiance (P800).

Associations between BCL-2 expression and different histopathological prognostic factors in different molecular subtypes of invasive breast carcinoma of no special type.

Background: Breast cancer is heterogeneous and the existing prognostic classifiers are limited in accuracy, leading to the unnecessary treatment of numerous women. B-cell lymphoma 2 (BCL-2), an anti-apoptotic protein, has been proposed as a marker of poor prognosis, associated with resistance to therapy in most tumor types expressing BCL-2. In breast cancer, however, BCL-2 expression has been reported to be a favorable prognostic factor.

Evaluating Dentists' Understanding of Dry Mouth Management: An International Cross-Sectional Study.

Objective: Studying dentists' knowledge of dry mouth management is crucial for effective diagnosis and treatment, improving patient outcomes and oral health. This study aimed to evaluate their knowledge and awareness of dry mouth and its predictors.

Materials And Methods: A pre-validated online survey was administered to a convenience sample of dentists across six countries.

Targeting the Sirtuin-1/PPAR-Gamma Axis, RAGE/HMGB1/NF-κB Signaling, and the Mitochondrial Functions by Canagliflozin Augments the Protective Effects of Levodopa/Carbidopa in Rotenone-Induced Parkinson's Disease.

Parkinson's disease (PD) is a pathological state characterized by a combined set of abnormal movements including slow motion, resting tremors, profound stiffness of skeletal muscles, or obvious abnormalities in posture and gait, together with significant behavioral changes. Until now, no single therapeutic modality was able to provide a complete cure for PD. This work was a trial to assess the immunomodulatory effects of canagliflozin with or without levodopa/carbidopa on rotenone-induced parkinsonism in Balb/c mice.

The Climate-Asthma Connection: Examining the Influence of Climate Change Anxiety on Asthma Control and Quality of Life: A Multi-National Study.

Aims: This study aims to identify the impact of climate change anxiety and asthma control on asthmatics' quality of life and examine the moderating role of climate change anxiety in this linkage.

Method: A multi-national cross-sectional study was conducted in four Arabian countries on 1266 asthmatics selected by convenience sampling. Data were collected from November 2023 to February 2024 using a climate anxiety scale, mini-asthma quality of life questionnaire, and an asthma control questionnaire.

Retrospective Analysis of Cerebrospinal Gushers in Cochlear Implant Surgery: Incidence, Risk Factors, and Outcomes-A Systematic Review and Meta-analysis.

Cerebrospinal fluid (CSF) gusher is a common complication experienced during cochlear implantation in patients with structural deformities in the inner ear. This study aimed to investigate the incidence of CSF gusher, risk factors, and outcomes in patients during cochlear implantation. This systematic review and meta-analysis were guided by the Preferred Reporting Items for Systematic Reviews and Meta-Analyses model.

Evaluation of cardiothoracic ratio as a potential predictor of cardiovascular abnormalities in individuals with type II diabetes mellitus: a case-control study.

Cardiovascular complications represent a significant health concern for individuals with diabetes mellitus. The relationship between diabetes and cardiovascular diseases is complex and multifaceted, involving a variety of pathophysiological mechanisms. This study aimed to investigate the potential role of the cardiothoracic ratio as a prognostic tool for cardiovascular disorders in patients with diabetes.

Randomized controlled trial parallel-group on optimizing community pharmacist's care for the elderly: The influence of WhatsApp-Email delivered clinical case scenarios.

Background: Drug-related problems (DRPs) significantly threaten the safety of the elderly. In order to improve pharmacists' ability to minimize these events, novel educational interventions that consider the current challenges in clinical practice are crucial.

Objectives: The primary objective is to assess the impact of two unique educational interventions on pharmacists' ability to identify DRPs.

Characteristics and risk factors associated with developing prediabetes in Saudi Arabia.

Objective: Prediabetes is prevalent in Saudi Arabia and globally. It is associated with adverse health outcomes and complications. Consequently, this study aimed to determine the risk factors associated with developing prediabetes in Saudi Arabia.

Dental students, interns, and junior dentists' awareness and attitude toward the inferior alveolar nerve block technique and related failure.

Background/purpose: Exploration of early practicing dental professionals' awareness and attitude toward inferior alveolar nerve block IANB will directly inform efforts to improve clinical practices and ensure patient safety. The aim was to highlight the students, interns, and junior dentists' awareness and attitude toward the IANB, failure, and related complications in the Kingdom of Saudi Arabia (KSA).

Materials And Methods: An open web-based survey prepared according to the Checklist for reporting results of Internet e-surveys CHERRIES recommendations was designed and carried out across different regions of the KSA.