Acute myocardial infarction complicated by cardiogenic shock in Ukraine: multicentre registry analysis 2021-2022.

Background: Data on the results and management strategies in patients with acute myocardial infarction complicated by cardiogenic shock (AMI-CS) in the Low and Lower-Middle Income Countries (LLMICs) are limited. This lack of understanding of the situation partially hinders the development of effective cardiogenic shock treatment programs in this part of the world.

Materials And Methods: The Ukrainian Multicentre Cardiogenic Shock Registry was analyzed, covering patient data from 2021 to 2022 in 6 major Ukrainian reperfusion centres from different parts of the country.

COVID-19 epidemiology and performance of the WHO clinical algorithm to diagnose COVID-19 in people with HIV from Ukraine.

Background: The two main objectives were to evaluate the COVID-19 point prevalence and the test performance of the WHO case definition to diagnose COVID-19 clinically in people with HIV in West Ukraine.

Methods: Multicenter cross-sectional study in Lviv, Ukraine, from October 2020-November 2021. COVID-19 unvaccinated people with HIV were included regardless of COVID-19 symptoms at routine clinical visits and had standardized medical, quality of life (EQ(5D)) and SARS-CoV-2 serology assessments.

Longitudinal Trends in Severe Dyslipidemia in the Czech Population: The Czech MONICA and Czech Post-MONICA Study.

Severe hypercholesterolemia is associated with an increase in the risk of developing atherosclerotic cardiovascular disease. The aim of this analysis was to assess longitudinal trends in severe dyslipidemia (defined as total cholesterol > 8 mmol/L or LDL-cholesterol > 5 mmol/L) in a representative population sample of the Czech Republic and to analyze the longitudinal trends in the basic characteristics of individuals with severe dyslipidemia. Seven independent cross-sectional surveys were organized in the Czech Republic to screen for major cardiovascular risk factors (from 1985 to 2015-2018).

VENOUS THROMBOEMBOLISM - PECULIARITIES OF COURSE IN EMERGENCY SURGERY DURING COVID-19 PANDEMIC.

Objective: The aim: To perform a comparative analysis of VTE in patients with acute surgical abdominal pathology before and during the COVID-19 pandemic.

Patients And Methods: Materials and methods: Retrospective study covered 53062 patients operated in the surgical clinic (Lviv city emergency hospital) in 2000-2019. Prospective analysis was based on the results of treatment of 546 patients operated at the same surgical clinic from April 2020 (1st surgical patient with COVID-19) till December 2021.

Sex differences in hypertension. Do we need a sex-specific guideline?

Hypertension is the most prevalent cardiovascular disorder and the leading cause of death worldwide in both sexes. The prevalence of hypertension is lower in premenopausal women than in men of the same age, but sharply increases after the menopause, resulting in higher rates in women aged 65 and older. Awareness, treatment, and control of hypertension are better in women.

Mixed Sexually Transmitted Infections in Infertile Couples: Empirical Treatment and Influence on Semen Quality.

Background: Trichomonas vaginalis (TV), Mycoplasma genitalium (MG) and Ureaplasma urealyticum (UU) are common sexually transmitted infections (STIs) that are diagnosed in infertile couples (cps). In cases with their simultaneous presence in a patient (mixed STI, MSTIs), treatment is complicated by the different sensitivity of microorganisms to antibacterial drugs. Moreover, in cases of complicated infections, the empirical treatment should be started before obtaining the results of drug susceptibilities.

Deviations of patients with drug addiction value and meaning sphere functioning.

Objective: The aim of this article is to study empirically drug addicts value-meaning sphere disorders.

Patients And Methods: Materials and methods: To study the drug addicts value-meaning sphere disorders indicators, Schwarz's «Value Questionnaire» and a structured interview of the respondents, aimed at studying the specifics of their meaning constructs, was used.

Results: Results: Meaning structure disorders are analyzed on the basis of the constructs and images of fixed imagination, which are used by drug addicts to describe the role of the addictive agent in their life, description.

Indicators of inflammation in the pathogenesis of unstable angina.

Objective: The aim: Research of blood lipid spectrum, level of anti-inflammatory cytokines and C-reactive protein of coronary heart disease patients.

Patients And Methods: Materials and methods: There was examined 61 patients with unstable angina, who had been on hospital care in the cardiology department of the Lviv National Emergency Hospital. Their average age was 68.

Condition of mineralized tooth tissue in a population of 15-year-old adolescents living in a region of Ukraine with slightly exceeded fluorine concentration in the water.

Introduction: Fluorine is a common element in nature; however, the difference between a beneficial dose and a toxic dose for the organisms is small. The main source of fluoride for humans is water in addition to food.

Objective: The aim of this study was to estimate the degree of severity of pathological changes, namely, caries or fluorosis, in the mineralized tooth tissue of 15-year-old adolescents with respect to their hygienic and nutritional habits, and the content of fluorine in drinking water, soil and plant products.

Minimally invasive and traditional operative techniques in surgical treatment of acute complicated pancreatitis.

Objective: Introduction: The issue of surgical treatment of acute pancreatitis, in particular the choice of operative technique, is becoming increasingly relevant. The aim: To work out surgical approach in patients with acute complicated pancreatitis (ACP) using minimally invasive and traditional operative techniques.

Patients And Methods: Materials and methods: 170 patients underwent surgery for ACP.

Physical activity as an important element in organizing and managing the lifestyle of populations in urban and rural environments.

Introduction: Physical activity is one of the basic needs of people throughout their lives. Physical activity prevents many diseases, including cardiovascular diseases, which have the highest mortality rate, both among urban and rural populations in Poland. The average life expectancy in Poland and the European Union is increasing.

Intensification of antiviral therapy for chronic hepatitis B with autoleukocyte immunization.

Introduction: The article presents a new method of intensification of antiviral therapy for chronic hepatitis B with intradermal autoleukocyte immunization during treatment with a drug of nucleotide analogues - tenofovir (patent UA 113873 U, 2017); other curative vaccines for chronic hepatitis B are also regarded.

Objective: The research involves patients with chronic hepatitis B (30), whose replication of HBV DNA decreased to a certain level after long-lasting (over 2 years) antiviral therapy, its further reduction ceased. These patients underwent intradermal autoleukocyte immunization for intensification of antiviral therapy.

The case of septical form of listeriosis with numerous abscesses of liver.

The article describes the case of a septic form of a listeriosis with multiple abscesses of the liver. Given clinical example illustrates the severe course of listeriosis with the development of septicemia and lesions of internal organs. Despite the adequate etiotropic and pathogenetic treatment for listeriosis meningoencephalitis, there was a lethal outcome of the disease.

Cholesterol-Based Grafted Polymer Brushes as Alignment Coating with Temperature-Tuned Anchoring for Nematic Liquid Crystals.

Novel alignment coating with temperature-tuned anchoring for nematic liquid crystals (NLCs) was successfully fabricated in three step process, involving polymerization of poly(cholesteryl methacrylate) (PChMa) from oligoproxide grafted to the glass surface premodified with 3-aminopropyltriethoxysilane. Molecular composition, thickness, wettability of the PChMa coating and its alignment action for a NLC were examined with time of flight-secondary ion mass spectrometry, ellipsometry, contact angle measurements, polarization optical microscopy and commercially produced PolScope technique allowing for mapping of the optic axis and optical retardance within the microscope field view. We find that the PChMa coating provides a specific monotonous increase (decrease) in the tilt angle of the NLC director with respect to the substrates normal upon heating (cooling) referred to as anchoring tuning.

Is Localized Scleroderma Caused by Borrelia burgdorferi?

Despite considerable achievements in the study of localized scleroderma, the etiology of the disease has not been investigated completely. Borrelia burgdorferi-the agent of Lyme disease-is suggested to be one of the possible etiological factors of localized scleroderma. However, among scientists, this hypothesis is quite controversial.

New Method of Inhibition of Activity of Tumor Necrosis Factor Alpha In Patients with Psoriasis.

Introduction: A new method of reduction of tumor necrosis factor alpha activity via intradermal immunization with inactivated autoleukocytes (patent UA97493 (2015) [1]) has been presented in the article. New patents from various countries have been analyzed [2-7].

Objective: Patients with psoriasis (24) with high level of tumor necrosis factor alpha in their blood (.

[The effect of long-chain polyunsaturated ω-3 fatty acids on the arterial stiffness parameters in patients with diabetes mellitus type 2 and cardiovascular autonomic neuropathy].

Objective: To analyze the effect of long-chain (LC) polyunsaturated w-3 fatty acids (PUFAs) on the daily arterial stiffness parameters in patients with type 2 diabetes (DM2) and cardiovascular autonomic neuropathy (CAN).

Material And Methods: The study involved 39 patients with DM2 and verified functional stage of CAN. Patients were divided into 2 groups: therapy group (n=21) and control group (n=18).

History of the terror of the communist regime of the Soviet Union in relation to doctors of Soviet Ukraine.

This paper presents information about the victimization of doctors, medical scientists and the staff of scientific and medical schools of soviet Ukraine, during the years from 1919 to 1953. It includes details of 622 doctors who were persecuted, of whom 142 were shot and 337 were deported to concentration camps. It describes the repression of Ukrainian medical scientists, of whom nearly 50 were arrested and 7 were shot.

The contribution of Ukrainian physicians to world medicine.

This paper gives information about fifty physicians, from the Middle Ages to the present, who have enriched world medicine. It describes the contribution made both by Ukrainian physicians and those of other nationalities, who worked in Ukrainian lands occupied by Russia, Poland, Austria-Hungary and Romania. The paper notes the contribution that these physicians have made to modern medical science, paying special attention to their achievements and published work.