3 results match your criteria: "Dansk Center for Aldringsforskning (DARC)[Affiliation]"
Article Synopsis
- Telomeres are protective DNA structures at the ends of chromosomes that are linked to cellular aging and show a negative correlation with chronological age in human tissues.
- While there is a weak connection between telomere length and overall mortality, they are thought to contribute to various age-related diseases.
- This has sparked interest in creating treatments aimed at elongating telomeres to potentially combat aging and its associated diseases.
Article Synopsis
- Telomeres help prevent cancer by limiting cell division, but short telomeres can also lead to chromosome instability, contributing to cancer development.!
- Certain diseases show a link between short telomeres and increased cancer risk, but using telomere length as a reliable cancer predictor has largely failed.!
- Scientists are exploring the connection between telomeres, telomerase, and cancer to create new treatment strategies in cancer therapy.!
In 2009 the Nobel Prize in Medicine was awarded to EH Blackburn, CW Greider and JW Szostak for their work on "How chromosomes are protected by telomeres and the enzyme telomerase". Telomeres are specialized DNA structures localized at the end of linear chromosomes. Telomeres are known as the biological clock of the cell, since they shorten with each cell division.
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