New metal complexes derived from a Schiff base called 3-acetylcoumarin benzoylhydrazone were synthesized, characterized, and analyzed using various spectroscopic techniques and computational methods.
The study revealed that the ligands exhibit different coordination dynamics in the complexes, showing tridentate and bidentate behavior depending on the metal ion involved.
The synthesized complexes demonstrated significant cytotoxic activity against human cancer cell lines, particularly complex C2, which outperformed the parent ligand and indicated enhanced anticancer properties when metal ions were incorporated.