1,802 results match your criteria: "Damascus University.[Affiliation]"

Introduction And Importance: This is a case of giant renal angiomyolipoma treated with partial nephrectomy without pre-embolization of the supplying arteries.

Case Presentation: The patient presented for regular checkup, a mass in the left flank was found on examination. No other symptoms were present.

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Article Synopsis
  • - The case discusses a 53-year-old man with alcoholic cardiomyopathy (ACM) who presented symptoms like shortness of breath and abdominal swelling, leading to a diagnosis of ACM, liver cirrhosis, and a rare isolated right atrial (RA) thrombus.
  • - Initial tests missed the RA mass, but advanced imaging techniques ultimately identified a large thrombus measuring 40x22x18 mm, prompting treatment with medication and a procedure called mechanical thrombectomy.
  • - The case highlights that isolated RA thrombosis is a rare complication of ACM, emphasizing the importance of using multiple imaging methods, especially transesophageal echocardiography, for accurate diagnosis and management in such cardiac cases.
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Study Objective: This study aims to assess the prevalence of both classic and non-classic pain sites in patients with ischemic heart disease, emphasizing the importance of recognizing and not disregarding non-classic symptoms.

Methods: This cross-sectional study included 100 patients diagnosed with coronary artery disease (CAD) who were admitted to two major hospitals in Syria. classic pain was identified as pain located in the precordial area, with or without radiation to the neck, jaw, left shoulder or arm.

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Background: Dental simulation games are virtual educational games that help children get familiar with different dental procedures. This study aimed to evaluate the pretreatment exposure to the "Baby Panda Dental Care" game in reducing pain and anxiety in comparison with the tell-show-do (TSD) technique during primary molars pulpotomy for patients aged 6-10 years.

Materials And Methods: It was a triple-blinded, two-arm, parallel-group, randomized, active-controlled trial.

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Total anomalous pulmonary venous connection is a rare congenital anomaly that has four anatomical subtypes. In the supracardiac type, the common pulmonary vein confluence usually drains into the left innominate vein via a vertical vein; however, it may drain into the superior vena cava. Herein, we present a successful surgical repair of a rare type of total anomalous pulmonary venous connection in which the common pulmonary vein confluence was draining directly into the superior vena cava without a vertical vein.

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This review delves into the intricate interplay between caffeine consumption and schizophrenia, examining evidence from epidemiological and clinical studies. While epidemiological research offers conflicting findings regarding the association between coffee intake and schizophrenia risk, clinical studies reveal diverse impacts of caffeine on symptomatology and cognition in individuals with schizophrenia. Some epidemiological studies suggest a potential protective effect of coffee consumption against schizophrenia, whereas others fail to establish a significant correlation.

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Breast self-examination among female medical students at Damascus University: A cross-sectional study.

Heliyon

August 2024

Professor of Medical Oncology, Vice Dean for Scientific Affairs, Faculty of Medicine, Damascus University, Almazzeh, Damascus, Syria.

Article Synopsis
  • Breast cancer is a major health issue in Syria, especially among young women, and breast self-examination (BSE) is emphasized as an important method for early detection due to limited access to medical centers for mammograms.
  • A cross-sectional study at Damascus University's medical faculties gathered data from 589 female students to assess their knowledge and attitudes toward BSE, using a structured online questionnaire.
  • Findings revealed that while most students had heard of BSE, only 57% had a positive attitude towards it, and many feared the implications of breast cancer, indicating a need for better education and awareness efforts.
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Osteochondromas, the most frequent type of bone tumor, develop from the metaphysis region of bones. Osteochondroma often occurs in bones, however, it is rare when it comes to rib tumors. It is often asymptomatic and observed incidentally.

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Introduction: Obesity is a worldwide pandemic that has many contributing factors. There is very scarce data available on this issue for the population in Syria. We aim to evaluate the body mass index and related obesity rates of medical students as they are the role model for the general population.

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Introduction: Celiac disease is a disease triggered by a protein called gluten. Celiac disease has intestinal and extraintestinal manifestations. Bronchiectasis is a permanent dilation of the bronchi that causes symptoms, such as cough producing a large amount of sputum, recurrent respiratory infections, and breathlessness.

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Introduction And Importance: This case study presents the clinical details of a 37-year-old woman who presented with an asymptomatic swelling in the right supraclavicular region, ultimately diagnosed as a carotid body tumor (CBT).

Case Presentation: The patient's medical background, which included her brother's CBT, prompted further investigation. Upon clinical examination and imaging studies, a tissue mass surrounding the right internal carotid artery was identified.

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Posterior fossa dermoid cysts are uncommon benign congenital abnormalities. Meningitis is seen as a primary symptom in these situations, more rarely we can find cerebral abscesses. In this case, we describe a 4-year-old Syrian boy who presented with headaches and frequent vomiting as his major complaints.

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Background It is difficult to determine the optimal method for restoring endodontically treated teeth, as several factors affect this decision. Functional requirements and the amount of remaining coronal tissue are considered the most important factors in choosing the best restoration for those teeth. Endocrown was introduced as a conservative alternative for endodontically treated and coronally damaged teeth.

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Background and objectives Mucogingival plastic surgery is a surgical procedure performed to prevent or correct anatomical, developmental, or traumatic defects. The problem of gingival recession is common in dental practice, causing pain and dentin hypersensitivity for the patient, and remains difficult to treat surgically at the second surgical site used to harvest the connective graft. Many alternatives have been used to replace connective grafts, but none have been as effective.

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Mediastinal diffuse large B-cell lymphoma (DLBC) may manifest in different presentations including systemic symptoms and local mass symptoms. We report two cases of diffuse large B-cell lymphoma presenting with pulmonary artery compression symptoms. The first case is of a 38-year-old Asian man which mimicked pulmonary embolism, and the second one is of a 27-year-old Asian woman who presented with fainting and respiratory symptoms due to local mass effect.

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Crosstalk between circular RNAs and the STAT3 signaling pathway in human cancer.

Biochim Biophys Acta Gene Regul Mech

December 2024

Department of Microbiology, Faculty of Veterinary Medicine, Hama University, Hama, Syria; Faculty of Dentistry, Arab Private University of science and Technology, Hama, Syria.

Article Synopsis
  • Circular RNAs (circRNAs) are unique RNA molecules formed by reverse splicing, and they play significant roles in cancer progression by affecting the STAT3 signaling pathway.
  • Research indicates that the expression of circRNAs related to STAT3 is often disrupted in various cancers, where they can either inhibit tumors or promote their growth.
  • This review highlights the need for further exploration of the relationship between circRNAs and the STAT3 pathway, suggesting that understanding this interaction could lead to new cancer treatment strategies.
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Social media has become a source of disseminating information to the public during the COVID-19 outbreak which has been a great advantage for healthcare centers. However, foreign anti-vaccination campaigns on social media increased the disbelief in vaccine safety. To our knowledge, the effects of social media on COVID-19 vaccine acceptance are not well-studied in low-income countries.

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Article Synopsis
  • Menstrual blood, often seen as waste, contains valuable health information through its components like endometrial cells and immune cells that can help diagnose various conditions such as hormonal imbalances and cervical cancer.
  • This review explores the potential for using menstrual blood as a non-invasive diagnostic tool, highlighting its composition and recent advancements in medical research.
  • It also addresses challenges in menstrual blood testing, such as ethical issues, lack of standardized collection methods, extensive validation needs, and societal stigma, which must be overcome to enhance personalized healthcare for menstruating individuals.
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Article Synopsis
  • Kimura's disease (KD) is a chronic inflammatory disorder that mainly affects the subcutaneous tissue, causing painless nodules and elevated eosinophil and IgE levels, particularly in the Asian region and Syria.
  • A 23-year-old male presented with swelling and pain in the preauricular area, systemic symptoms, and significant weight loss over seven months before being diagnosed with KD after a fine-needle aspiration showed no abnormal cells.
  • This case is notable as the second recorded instance of KD in Syria and highlights the need for further research on its prevalence and effective treatment options.
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Introduction And Importance: Hydatid cyst disease is a zoonotic disease caused by and is recognized as a significant health issue in many countries, particularly Mediterranean countries. Hydatid cysts in the musculoskeletal system are rare, with only a few reported cases. These usually occur as secondary cysts resulting from the hematogenous dissemination from primary sites.

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Treatment of recurrent uveitis and ankylosing spondylitis with Golimumab: a case report, Letter to Editor.

Ann Med Surg (Lond)

August 2024

Department of Rheumatology, Faculty of Medicine, Damascus University, Damascus, Syrian Arab Republic.

Article Synopsis
  • Uveitis is a common complication in about 23% of ankylosing spondylitis patients, posing significant treatment challenges.
  • A 32-year-old male who had recurrent anterior uveitis and inflammatory back pain was eventually diagnosed with ankylosing spondylitis and found clinical remission after starting Golimumab.
  • Clinical guidelines support using drugs like etanercept and adalimumab for recurrent uveitis in ankylosing spondylitis, but Golimumab has also shown effectiveness in difficult cases resistant to other treatments.
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Primary Sjögren's syndrome without ocular manifestation: a case report.

Ann Med Surg (Lond)

August 2024

Department of Rheumatology, Faculty of Medicine, Damascus University, Damascus, Syria.

Introduction And Importance: Sjögren's Syndrome is a systemic immune disorder, manifested in dry eyes and mouth. Primary Sjögren's syndrome without ocular manifestation is seldom mentioned in the literature.

Case Presentation: The authors report a case of a 48-year-old female who complained of dryness of mouth and dysphagia for 6 months.

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Background: Opalski syndrome is a rare variant of Wallenberg syndrome (lateral medullary syndrome) that demonstrates concomitant ipsilateral hemiplegia due to infarctions within the lateral medulla and the cervical spinal cord, which also extend to the post-pyramidal decussation to affect the corticospinal tract.

Case Presentation: A 56-year-old man initially presented with a unilateral headache with right cervical pain. Consequently, he developed symptoms that indicate Wallenberg syndrome: vertigo, dysphonia, dysarthria, right limb ataxia with a tendency to fall, and ptosis, in addition to ipsilateral hemiparesis.

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Background: Warfarin patients who need dental extraction face the problem of bleeding and no sufficient hemostasis results in dry socket and postoperative pain. This study aimed to evaluate and compare the efficacy of the topical application of tranexamic acid-soaked absorbable Gelfoam (TXA-Gel) and saline-soaked absorbable Gelfoam (saline-Gel) in relieving postoperative pain following bilateral simple extraction of permanent mandibular molars in warfarin patients.

Methods: This was a randomized, triple-blinded, split-mouth, active-controlled clinical trial.

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Background And Objectives: Surface roughness is one of the most important factors that play an important role in increasing the connection between the surface of the tooth and the applied restoration. Due to the increased interest in zirconia and the improvement of its mechanical and aesthetic properties, studies have increased that work to improve and increase its surface roughness so that it can be used as a veneer in the future. This study aims to compare the effect of two types of lasers on the surface of highly transparent zirconia to evaluate the surface roughness resulting from the two techniques.

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