Expression of glucocorticoid receptor isoforms and associations with serine/arginine-rich protein 30c and 40 in patients with systemic lupus erythematosus.

Objectives: To investigate the expression of glucocorticoid receptor (GR) isoforms in patients with systemic lupus erythematosus (SLE), confirm the main GR isoforms involving in glucocorticoids (GC) resistance, and explore the associations of GR isoforms with serine/arginine-rich protein (SRp) 30c and SRp40.

Methods: Seventy patients with SLE and thirty-eight age- and sex-matched controls were recruited. All patients received prednisone (0.

Clinicopathological analysis on small cell carcinoma of the prostate in chinese patients.

Objective: To explore the clinical and pathological characteristics of small-cell carcinoma (SmCC) of the prostate and applicable treatment methods.

Methods: We reported three cases of SmCC of the prostate diagnosed from 1999 to 2011 at the Chinese PLA General Hospital. We also reviewed clinical and pathological data of 26 cases in China reported over the same period.

A case of biliary cystadenocarcinoma with malignant seeding of the tract after percutaneous catheter drainage.

Biliary cystadenocarcinoma is rare tumor that originates from the hepatobiliary epithelium, and its clinical diagnosis is difficult during the preoperative course. A 65-year-old woman with biliary cystadenocarcinoma was misdiagnosed as hepatic abscess and underwent ultrasonography-guided percutaneous catheter drainage. Ten months later, the patient was re-admitted to our department with a mucin-producing cauliflower-like mass measuring 10x10x5 cm³ at the site of puncture.

[Progression of preoperative regional arterial infusion chemotherapy in advanced gastric cancer].

The outcome of surgery alone for advanced gastric cancer is unsatisfactory. Local recurrence rate and distant metastasis rate are still high in postoperative patients. In recent years, people have paid more attention to neo- adjuvant chemotherapy, because it can reduce tumor loading, degrade the staging, increase the surgery excision rate and improve the long-term survival.

Long-term outcome of patients with lamivudine after early cessation of hepatitis B immunoglobulin for prevention of recurrent hepatitis B following liver transplantation.

Background: The aim of this study is to examine the efficacy of long-term prophylaxis with lamivudine (LAM) after a course of post-operative hepatitis B immunoglobulin (HBIG) in patients who underwent liver transplantation (LT) for hepatitis B virus (HBV)-related disease.

Result: The medical records of HBV-infected patients who underwent a LT in our institution between July 2001 and May 2005 were reviewed. There were 15 liver transplant recipients who were administered HBIG for <18 months and used LAM as a maintenance prophylaxis regime enrolled in this study.

[The prevention of hepatolithiasis and biliary stricture post choledochojejunostomy].

Objective: To investigate the prevention of hepatolithiasis and biliary stricture post choledochojejunostomy using choledochoscopy technique and evaluate feasibility and efficacy of choledochojejunostomy and artificial valve of efferent loop in preventing reflux.

Methods: To analyze the data of 47 patients with hepatolithiasis who had been operated with Roux-en-Y cholangiojejunostomy and artificial valve of efferent loop to prevent bilio-intestinal regurgitation. Of the patients, 19 were marked with silver nip at the jejunum export of bilio-intestinal anastomosis.

[Relationship between chemosensitivity in vitro and the expression of GRP78 in non-small cell lung cancer].

Background: The expressive level of glucose-regulated protein 78 (GRP78) is elevated and correlated with resistance of chemotherapy drugs in breast cancer cell. However, little is known about the relationship between its expression and drug resistance in non-small cell lung cancer (NSCLC). The aim of this study was to explore the relationship between drug resistance and the expression of GRP78 in NSCLC.

[Preoperative superselective intra-internal iliac arterial chemotherapy for invasive bladder cancer and curative analysis].

Objective: To study clinical effects of preoperative intra-internal iliac-arterial chemotherapy for invasive bladder cancer.

Methods: 14 cases of invasive bladder cancer underwent superselective intra-internal iliac-arterial chemotherapy before conservative cystectomy.

Results: After 2-3 week therapy, reduction of cancer volume (20%-50%), clotted by thrombus in the blood vessels of the cancer or circumferential tissue, and decreased bleeding were found.

[The experiment research of OB glue used in tracheoanastomosis].

Resect a segment of canine cervical trachea. The length of resected trachea is from 1-4cm and 5-8cm. In the first group, one dog was used for each length and two dogs were used for each length in the second group, therefore twelve were used in the experiment.