Management of depression. Current trends in primary care.

Depression is a common illness that may be difficult to detect, especially in patients with concurrent illness. Fortunately, depression is usually treatable. Identifying the optimal antidepressant agent requires careful consideration of the patient's age, health status, and history of response to antidepressants.

Adult meningitis. Rapid identification for prompt treatment.

To be effective, treatment of meningitis should be based on the history and physical examination, careful examination of the cerebrospinal fluid, and good clinical judgment regarding the most likely pathogen. Meningitis in adults is usually caused by certain common viruses and bacteria, although atypical pathogens should be considered in immunocompromised patients. Supportive therapy measures are appropriate for viral disease, and intravenous acyclovir (Zovirax) may be given if infection with herpes simplex virus is suspected.