The Usefulness of Carotid Artery Doppler Measurement as a Predictor of Early Death in Sepsis Patients Admitted to the Emergency Department.

This study aims to verify whether the blood flow velocity and the diameter size, measured through intra-carotid artery Doppler measurements performed on sepsis patients visiting the emergency department, are useful as tools for predicting the risk of early death. As a prospective study, this research was performed on sepsis patients who visited a local emergency medical center from August 2021 to February 2023. The sepsis patients' carotid artery was measured using Doppler imaging, and they were divided into patients measured for the size of systolic and diastolic mean blood flow velocity and diameter size: those measured for their qSOFA (quick sequential organ failure assessment) score and those measured using the SIRS (systemic inflammatory response syndrome) criteria.

Gut microbiome and metabolome signatures in liver cirrhosis-related complications.

Background/aims: Shifts in the gut microbiota and metabolites are interrelated with liver cirrhosis progression and complications. However, causal relationships have not been evaluated comprehensively. Here, we identified complication-dependent gut microbiota and metabolic signatures in patients with liver cirrhosis.

Multistrain Probiotics Alleviate Diarrhea by Modulating Microbiome-Derived Metabolites and Serotonin Pathway.

Diarrhea, a common gastrointestinal symptom in health problems, is highly associated with gut dysbiosis. The purpose of this study is to demonstrate the effect of multistrain probiotics (Sensi-Biome) on diarrhea from the perspective of the microbiome-neuron axis. Sensi-Biome (Lactiplantibacillus plantarum, Bifidobacterium animalis subsp.

The Effects of an App-Based Physical Activity Program on Colorectal Cancer Patients Undergoing Chemotherapy: A Randomized Controlled Trial.

Background: Colorectal cancer is one of the most common malignancies worldwide. Oxaliplatin, which is used as adjuvant chemotherapy, affects quality of life by causing oxaliplatin-induced peripheral neuropathy in colorectal cancer patients.

Objectives: This study examined the effects of an application (app)-based physical activity program for alleviating peripheral neuropathy symptoms in colorectal cancer patients undergoing chemotherapy.

Straightforward Magnetic Resonance Temperature Measurements Combined with High Frame Rate and Magnetic Susceptibility Correction.

Proton resonance frequency shift (PRFS) is an MRI-based simple temperature mapping method that exhibits higher spatial and temporal resolution than temperature mapping methods based on T1 relaxation time and diffusion. PRFS temperature measurements are validated against fiber-optic thermal sensors (FOSs). However, the use of FOSs may introduce temperature errors, leading to both underestimation and overestimation of PRFS measurements, primarily due to material susceptibility changes caused by the thermal sensors.

Multi-strain probiotics alleviate loperamide-induced constipation by adjusting the microbiome, serotonin, and short-chain fatty acids in rats.

Constipation is one of the most common gastrointestinal (GI) disorders worldwide. The use of probiotics to improve constipation is well known. In this study, the effect on loperamide-induced constipation by intragastric administration of probiotics Consti-Biome mixed with SynBalance® SmilinGut ( PBS067, LRH020, subsp.

-derived short-chain fatty acids and indole compounds attenuate nonalcoholic fatty liver disease by modulating gut-liver axis.

Emerging evidences about gut-microbial modulation have been accumulated in the treatment of nonalcoholic fatty liver disease (NAFLD). We evaluated the effect of and on the NAFLD pathology and explore the molecular mechanisms based on multi-omics approaches. Human stool analysis [healthy subjects ( = 25) and NAFLD patients ( = 32)] was performed to select NAFLD-associated microbiota.

Standardized patient experiences study on clinical performance evaluation of nursing college students' ability: A qualitative study.

Background: Nursing students' direct exposure to patients is limited, thus affecting their performance in practical clinical settings in the healthcare field, including hospitals or communities. Therefore, various clinical situation scenarios, using standardized patients trained to act like real patients (i.e.

Abnormal thalamocortical connectivity of preterm infants with elevated thyroid stimulating hormone identified with diffusion tensor imaging.

While thyroid disturbances during perinatal and postnatal periods in preterm infants with congenital hypothyroidism reportedly disrupt neuronal development, no study has considered the effect of thyroid disturbances in premature infants with subclinical hypothyroidism with elevations of thyroid stimulating hormone. We aimed to identify altered fiber integrity from the thalamus to cortices in preterm infants with subclinical hypothyroidism. All preterm infants born were categorized according to thyroid stimulating hormone levels through serial thyroid function tests (36 preterm controls and 29 preterm infants with subclinical hypothyroidism).

Development of a scale for assessing meal satisfaction in older adults: Meal satisfaction assessment questionnaire (MSAQ).

This meal satisfaction assessment questionnaire for older adults (MSAQ) focuses on assessing meal satisfaction rather than only measuring physical functioning or the risk of malnutrition in older people. By looking at the factors that influence meal satisfaction in older adults through a comprehensive literature review, this study develops a scale for measuring meal satisfaction in older people. For content and face validation, a 61-item questionnaire was administered to 290 people using a five-point scale.

The Effects of Forest Therapy on Immune Function.

We conducted a systematic review of the effects of a forest therapy program on adults' immune function. We used PICO-SD (participants, interventions, comparisons, outcomes, study design) to identify key items. The participants were adults over the age of 18 and the intervention was forest therapy.

Comparing audio- and video-delivered instructions in dispatcher-assisted cardiopulmonary resuscitation with drone-delivered automatic external defibrillator: a mixed methods simulation study.

This study compared first responders' cardiopulmonary resuscitation (CPR) performance when a dispatcher provides audio instructions only and when both audio and video instructions are given. In the simulation, an automatic external defibrillator (AED) was delivered via drone in response to a cardiac arrest occurring outside a hospital setting. Participants' qualitative experiences were also explored.

Analysis of Children's Physical Characteristics Based on Clustering Analysis.

This study assessed the physical development, physical fitness (muscular endurance, muscular strength, flexibility, agility, power, balance), and basal metabolic rate (BMR) in a total of 4410 children aged six (73-84 months) residing in Korea. Their physical fitness was visually classified according to the physical fitness factor and-considering that children showed great variations in the physical fitness criteria depending on their physique and body composition-the study aimed to assess characteristics such as physique and BMR, the precursor for fat-free mass, based on the physical health clusters selected through a multivariate approach. As a result, the physical health clusters could be subdivided into four clusters: balance (1), muscular strength (2), low agility (3), and low physical fitness (3) cluster.

Effect of Korea red ginseng on nonalcoholic fatty liver disease: an association of gut microbiota with liver function.

Background: Korea Red Ginseng (KRG) has been used as remedies with hepato-protective effects in liver-related condition. Microbiota related gut-liver axis plays key roles in the pathogenesis of chronic liver disease. We evaluated the effect of KRG on gut-liver axis in patients with nonalcoholic statohepatitis by the modulation of gut-microbiota.

Nutritional Status and Diet Style Affect Cognitive Function in Alcoholic Liver Disease.

Malnutrition and cognitive dysfunction are typical features of alcoholic liver disease (ALD) and are correlated with the development of complications. The aim of this study is to explore the effect of nutritional state and diet on cognitive function in ALD. A total of 43 patients with compensated alcoholic cirrhosis were enrolled, and a neuropsychological test was assessed according to body mass index (BMI, <22 and ≥22).

Development and Validation of the Happiness Scale for Middle-Aged Women Based on Existence, Relation, and Growth Theory.

Purpose: This study aimed at developing a happiness assessment scale for middle-aged women (HAS-MW) in Korea.

Methods: Preliminary items for the scale were drafted from the results of literature review and personal interviews and open-ended questions with women in the community. The interviews were based on the theory of existence, relatedness, and growth.

Propagation and Attenuation Characteristics of an Ultrasonic Beam in Dissimilar-Metal Welds.

Ultrasonic inspection of welds joining dissimilar metals in nuclear power plants has proven to be a challenge, because the ultrasonic waves are subject to diffraction, distortion, scattering, and noise. These perturbations are due to their interactions with coarse-grained microstructures having anisotropic and heterogeneous metallurgical properties that can promote ultrasonic attenuation. In this paper, to improve the reliability of ultrasonic testing for dissimilar-metal welds (DMWs), ultrasonic beam characteristics for DMWs with a buttering layer were investigated in order to analyze the beam distortion phenomenon caused by inhomogeneous anisotropic properties and coarse grains.

Mechanical Properties of Coal Ash Particle-Reinforced Recycled Plastic-Based Composites for Sustainable Railway Sleepers.

This experimental research investigates the mechanical properties of municipal plastic waste-based particulate composites reinforced with coal ash (CA), the by-product of thermal power plants, for sustainable railway sleepers. Six series of sustainable composites filled with inorganic mineral fillers, including CA, were prepared by a twin-screw extruder and a compression molding machine. The effect of mix design variables-such as filler type, contents and the particle size of the filler-on mechanical properties-including tensile, compression and flexural properties-and morphology were characterized.

and ameliorate progression of non-alcoholic fatty liver disease through modulation of the gut microbiome.

Targeting the gut-liver axis by modulating the gut-microbiome can be a promising therapeutic approach in nonalcoholic fatty liver disease (NAFLD). The aim of this study was to evaluate the effects of single species and a combination of and in NAFLD mice model. Six-week male C57BL/6J mice were divided into 9 groups (n = 10/group; normal, Western diet, and 7 Western diet-strains [10 CFU/g, 8 weeks]).

The Factors Influencing Meal Satisfaction in Older Adults: A Systematic Review and Meta-analysis.

Purpose: The aim of this study was to identify factors influencing meal satisfaction in older adults.

Methods: Authors searched four databases Ovid MEDLINE, Ovid EMBASE, the Cochrane Library, and KoreaMed using the following key search terms: "(elderly-mp. OR aged), AND (meal OR food OR eating OR feeding), AND satisfaction.

Effects of the Computer Desk Level on the Musculoskeletal Discomfort of Neck and Upper Extremities and EMG Activities in Patients with Spinal Cord Injuries.

Background: Computers are used as a means of social communication, for work and other purposes. However, patients with spinal cord injuries may have a higher risk than normal individuals with musculoskeletal problems when using computers owing to their inability to control respective postures due to problems in motor and sensory functioning.

Objectives: This study is aimed at identifying the effect of computer desk heights on musculoskeletal discomforts of the neck and upper extremities and EMG activities in patients with spinal cord (C6) and upper thoracic spinal cord injuries.

Immunological measurement of aspartate/alanine aminotransferase in predicting liver fibrosis and inflammation.

Background/aims: Enzymatic analysis of aspartate/alanine aminotransferase (AST/ALT) does not exactly represent the progression of liver fibrosis or inflammation. Immunoassay for AST (cytoplasmic [c] AST/mitochondrial [m] AST) and ALT (ALT1/ALT2) has been suggested as one alternatives for enzymatic analysis. The objective of this study was to evaluate the efficacy of immunoassay in predicting liver fibrosis and inflammation.

Influence of proprioceptive neuromuscular facilitation therapeutic exercise on woman with temporomandibular joint disorder: a case study.

The purpose of this study was to determine the effect of therapeutic exercise for a woman with temporomandibular joint disorder. She was 31 year old and had limitation in the opening of mouth. When opening the mouth, she complained pain in the temporomandibular joint and noise.