Teaching an Adult with ASD Independent Toileting Skills.

Independence with the toilet is an important life skill. Individuals with Autism Spectrum Disorder (ASD) may present with several deficits that impair their ability to independently use the toilet and often individuals with ASD require more support than is provided in typical toilet training methods, including behavioral toilet training methods. This current study is a demonstration of the use of an intensive toilet training procedure with one eighteen-year-old adult male with ASD and below-average levels of adaptive functioning to successfully void in the toilet and reduce accidents.

Comparative Analysis of Medical School and Physician Assistant Education and the Use of Provisional Licenses.

The current shortage of physicians in the United States has prompted a reevaluation of medical education and licensure pathways. This paper analyzes medical school and physician assistant education, highlighting the differences in training, clinical experience, and licensing requirements. Additionally, the paper explores the emerging role of postgraduate licensure (PGL) programs, which allow unmatched medical graduates to obtain provisional licenses and practice under attending physician supervision.

A spin-flip study of the diradical isomers of pyrrole, furan, and thiophene.

Heteroaromatic species are commonly found in complex gaseous mixtures, from tobacco smoke to petroleum and asphaltene combustion products. At high temperatures, C-H bond rupture produces various dehydro radical isomers. We have used the spin-flip formulation of equation-of-motion coupled cluster theory with single and double substitutions (EOM-SF-CCSD) to characterize the energies and wave functions of the lowest lying singlet and triplet states of the diradical (2,3), (2,4), (2,5), and (3,4) di-dehydro isomers of pyrrole, furan, and thiophene.

Prey size and ecological separation in spinosaurid theropods based on heterodonty and rostrum shape.

Members of the dinosaur clade Spinosauridae had numerous traits attributed to feeding in or around water, and their feeding apparatus has often been considered analogous to modern crocodylians. Here we quantify the craniodental morphology of Spinosauridae and compare it to modern Crocodylia. We measured from spinosaurid and crocodylian skeletal material the area of alveoli as a proxy for tooth size to determine size-heterodonty.

Comparing development-matched and age-matched play targets: A replication and extension.

Previous research has supported selecting development-matched targets rather than age-matched targets to teach play skills to children with autism spectrum disorder. However, few studies have been conducted, and replications and extensions of this research are needed. The current study replicated Pane et al.

Tau pathology in the dorsal raphe may be a prodromal indicator of Alzheimer's disease.

Protein aggregation in brainstem nuclei is thought to occur in the early stages of Alzheimer's disease (AD), but its specific role in driving prodromal symptoms and disease progression is largely unknown. The dorsal raphe nucleus (DRN) contains a large population of serotonin (5-hydroxytryptamine; 5-HT) neurons that regulate mood, reward-related behavior, and sleep, which are all disrupted in AD. We report here that tau pathology is present in the DRN of individuals 25-80 years old without a known history of dementia, and its prevalence was comparable to the locus coeruleus (LC).

Reliability of Goniometric Techniques for Measuring Hip Flexor Length Using the Modified Thomas Test.

Background: The modified Thomas test (MTT) is commonly used to assess the flexibility of hip musculature, including the iliopsoas, rectus femoris, and tensor fascia latae. This measurement is important to include in a comprehensive musculoskeletal examination. However, existing research shows conflicting results regarding its reliability, particularly due to variations in controlling pelvic tilt during testing, which may lead to inaccurate measurements of hip extension when quantifying the test outcomes.

Iron-coated Komodo dragon teeth and the complex dental enamel of carnivorous reptiles.

Komodo dragons (Varanus komodoensis) are the largest extant predatory lizards and their ziphodont (serrated, curved and blade-shaped) teeth make them valuable analogues for studying tooth structure, function and comparing with extinct ziphodont taxa, such as theropod dinosaurs. Like other ziphodont reptiles, V. komodoensis teeth possess only a thin coating of enamel that is nevertheless able to cope with the demands of their puncture-pull feeding.

Reliability of a Musculoskeletal Imaging Competency Examination for Physical Therapists.

Introduction: The Burley Readiness Examination (BRE) for Musculoskeletal (MSK) Imaging Competency assesses physical therapists' baseline MSK imaging competency. Establishing its reliability is essential to its value in determining MSK imaging competency. The purpose of this study was to test the reliability of the BRE for MSK Imaging Competency among physical therapists (PTs) with varying levels of training and education.

Interaction of serotonin/GLP-1 circuitry in a dual preclinical model for psychiatric disorders and metabolic dysfunction.

Isolation of rodents throughout adolescence is known to induce many behavioral abnormalities which resemble neuropsychiatric disorders. Separately, this paradigm has also been shown to induce long-term metabolic changes consistent with a pre-diabetic state. Here, we investigate changes in central serotonin (5-HT) and glucagon-like peptide 1 (GLP-1) neurobiology that dually accompany behavioral and metabolic outcomes following social isolation stress throughout adolescence.

Applying the 2022 Cardiovascular and Pulmonary Entry-Level Physical Therapist Competencies to Physical Therapist Education and Practice.

Background And Purpose: Competency-based education (CBE) is an emerging topic within physical therapy (PT). It has emerged to assure all stakeholders that physical therapist education program graduates are proficient in the requisite knowledge, skills, and behaviors (KSBs) essential for entry-level practice. Competencies have existed within cardiovascular and pulmonary (CVP) PT since 1980, updated in 2008, and most recently updated in 2022.

Validation of the Survey of Sleep Quality in the Pediatric Intensive Care Unit (SSqPICU).

Study Objectives: Observational data suggest pediatric intensive care unit-related sleep and circadian disruption (PICU-SCD) affects many critically ill children. Multicenter trials exploring PICU-SCD have been impractical because measuring sleep in this setting is challenging. This study validates a questionnaire for caregivers to describe children's sleep in the PICU.

Starting the Conversation Around the Ethical Use of Artificial Intelligence in Applied Behavior Analysis.

Artificial intelligence (AI) is increasingly a part of our everyday lives. Though much AI work in healthcare has been outside of applied behavior analysis (ABA), researchers within ABA have begun to demonstrate many different ways that AI might improve the delivery of ABA services. Though AI offers many exciting advances, absent from the behavior analytic literature thus far is conversation around ethical considerations when developing, building, and deploying AI technologies.

The Promises and Possibilities of Artificial Intelligence in the Delivery of Behavior Analytic Services.

Artificial intelligence (AI) has begun to affect nearly every aspect of our daily lives and nearly every industry and profession. Many readers of this journal likely work in one or more areas of behavioral health. For readers who work in behavioral health and who are interested in AI, the purpose of this article is to highlight the pervasiveness of AI research being conducted around many facets of behavioral health service delivery.

Optimizing schools of cytology: Discussions from the 2022 ASC/IAC Cytology Education Symposium, North American Strategies, and European Symbiosis.

This report highlights information and outcomes from the November 2022 ASC/IAC joint Cytology Education Symposium, an annual conference organized by the Cytology Programs Review Committee. The manuscript provides information on shared educational opportunities and practices for cytology students and other learners in anatomic pathology, discusses recruitment strategies for schools of cytology, conveys teaching resources, introduces perspectives on virtual microscopy and online learning, and transmits information about wellness of students in schools of cytology.

Variations on the Bergman Cyclization Theme: Electrocyclizations of Ionic Penta-, Hepta-, and Octadiynes.

The Bergman cyclization of ()-hexa-3-ene-1,5-diyne to form the aromatic diradical -benzyne has garnered attention as a potential antitumor agent due to its relatively low cyclization barrier and the stability of the resulting diradical. Here, we present a theoretical investigation of several ionic extensions of the fundamental Bergman cyclization: electrocyclizations of the penta-1,4-diyne anion, hepta-1,6-diyne cation, and octa-1,7-diyne dication, leveraging the spin-flip formulation of the equation-of-motion coupled cluster theory with single and double substitutions (EOM-SF-CCSD). Though the penta-1,4-diyne anion exhibits a large cyclization barrier of +66 kcal mol, cyclization of both the hepta-1,6-diyne cation and octa-1,7-diyne dication along a previously unreported triplet pathway requires relatively low energy.

Disordered eating is not associated with musculoskeletal injury in university athletes.

Musculoskeletal injuries and disordered eating are prevalent in varsity-level athletes but are not associated in our participants.

Alcohol inhibits sociability via serotonin inputs to the nucleus accumbens.

Social interaction is a core component of motivational behavior that is perturbed across multiple neuropsychiatric disorders, including alcohol use disorder (AUD). Positive social bonds are neuroprotective and enhance recovery from stress, so reduced social interaction in AUD may delay recovery and lead to alcohol relapse. We report that chronic intermittent ethanol (CIE) induces social avoidance in a sex-dependent manner and is associated with hyperactivity of serotonin (5-HT) neurons in the dorsal raphe nucleus (DRN).

Commentary: Is Wearable Fitness Technology a Medically Approved Device? Yes and No.

Wearable technologies, i.e., activity trackers and fitness watches, are extremely popular and have been increasingly integrated into medical research and clinical practice.

Physical therapy students' application of an imaging decision rule for acute knee pain.

Background: Evidence supports direct referral for imaging by physical therapists. Accuracy and self-efficacy for imaging decisions have not been investigated in entry-level doctor of physical therapy (DPT) students.

Objective: The purpose of this study was to understand the relationship between entry-level DPT instruction and accuracy and self-efficacy for imaging referral due to acute knee trauma.