Prebiotics: Comprehensive analysis of sources, structural characteristics and mechanistic roles in disease regulation.

Prebiotics are nondigestible components that comprise short-chain carbohydrates, primarily oligosaccharides, which are converted into beneficial compounds by probiotics. Various plant substances with prebiotic properties provide substantial health benefits and are used to prevent different diseases and for medical and clinical applications. Consuming prebiotics gives impeccable benefits since it aids in gut microbial balance.

RT-qPCR Analysis of Inflammatory & Apoptotic Factors-Related Gene Expression in ZIKV-Infected IFNAR1 Mice.

ZIKV was a mosquito-borne neglected tropical pathogen until it spread into the Pacific and South America, followed by large human outbreaks related to congenital abnormalities in neonates and neurological disorders in adults. The following study used the C57BL/6 IFNAR1 receptor knockout (IFN AR1) mouse model to understand the role of selected cytokines and apoptotic factors in the pathogenicity of ZIKV strain PRVABC59. Mice infected with 10 particles of Zika viruses died until 9 days post infection.

Mitoquinone improves porcine embryo development through modulating oxidative stress and mitochondrial function.

Oxidative stress caused by excess reactive oxygen species (ROS) is one of the main causes of low efficiency in in vitro production of embryos. These ROS can cause mitochondrial dysfunction and apoptosis, resulting in poor embryo development. Therefore, to prevent mitochondrial damage and apoptosis caused by ROS, we investigated the effects of mitoquinone (MitoQ), a mitochondrial-targeted antioxidant, on the in vitro culture (IVC) of porcine embryos.

Active maintenance of working memory contents affects functioning of attentional filtering.

Salient objects are well known to capture attention. Furthermore, a stimulus associated with the attention-capturing objects could infiltrate into working memory. This was recently formulated as filter disruption theory.

Quality Variation of Pork Bellies by Cutting Manner and Quality Grade.

In the meat industry, the quality grading system is commonly applied to classify carcasses based on quality and value. Presently, to facilitate consumer convenience, pork bellies are prepared into slices and retailed in supermarkets and butchers. The objective of this study was to assess the effect of quality grade (QG) and retail cutting manner on the quality properties of pork bellies.

A Simulation-Based Approach for Evaluating the Effectiveness of Robotic Automation Systems in HMR Product Loading.

The food industry has tried to enhance production processes in response to the increasing demand for safe, high-quality Home Meal Replacement (HMR) products. While robotic automation systems are recognized for their potential to improve efficiency, their high costs and risks make them less accessible to small and medium-sized enterprises (SMEs). This study presents a simulation-based approach to evaluating the feasibility and impact of robotic automation on HMR production, focusing on two distinct production cases.

Screening Germplasms and Detecting Quantitative Trait Loci for High Sucrose Content in Soybean.

Sucrose is a desirable component of processed soybean foods and animal feed, and thus, its content is used as an important characteristic for assessing the quality of soybean seeds. However, few studies have focused on the quantitative trait loci (QTLs) associated with sucrose regulation in soybean seeds. This study aims to measure the sucrose content of 1014 soybean accessions and identify genes related to high sucrose levels using QTL analysis.

Recent Methods for Evaluating Crop Water Stress Using AI Techniques: A Review.

This study systematically reviews the integration of artificial intelligence (AI) and remote sensing technologies to address the issue of crop water stress caused by rising global temperatures and climate change; in particular, it evaluates the effectiveness of various non-destructive remote sensing platforms (RGB, thermal imaging, and hyperspectral imaging) and AI techniques (machine learning, deep learning, ensemble methods, GAN, and XAI) in monitoring and predicting crop water stress. The analysis focuses on variability in precipitation due to climate change and explores how these technologies can be strategically combined under data-limited conditions to enhance agricultural productivity. Furthermore, this study is expected to contribute to improving sustainable agricultural practices and mitigating the negative impacts of climate change on crop yield and quality.

ROS Gateway: Enhancing ROS Availability across Multiple Network Environments.

As the adoption of large-scale model-based AI grows, the field of robotics is undergoing significant changes. The emergence of cloud robotics, where advanced tasks are offloaded to fog or cloud servers, is gaining attention. However, the widely used Robot Operating System (ROS) does not support communication between robot software across different networks.

Effect of Endurance Exercise Training on Gut Microbiota and ER Stress.

Regular exercise as part of one's lifestyle is well-recognized for its beneficial effect on several diseases such as cardiovascular disease and obesity; however, many questions remain unanswered regarding the effects of exercise on the gut environment. This study aimed to investigate the impact of long-term endurance exercise on modulating inflammation and endoplasmic reticulum (ER) stress. Fifteen-week-old male Sprague-Dawley (SD) rats were subjected to six months of endurance treadmill training, while age-matched controls remained sedentary.

Experimental Evaluation of Geometric and Environmental Effects on Mechanically Fastened Non-Crimp Fabric Composites.

Corresponding to marine environmental regulations is important in shipbuilding and marine industries. The application of lightweight composite materials on ships is an effective approach to reducing the emission of greenhouse gases. The mechanical fastening method is a good candidate to assemble composites and conventional metals.

RETRACTED: Lee et al. Myogenesis Effects of RGX365 to Improve Skeletal Muscle Atrophy. 2023, , 4307.

The journal retracts the article, "Myogenesis Effects of RGX365 to Improve Skeletal Muscle Atrophy" [...

Revolutionizing Molecular Design for Innovative Therapeutic Applications through Artificial Intelligence.

The field of computational protein engineering has been transformed by recent advancements in machine learning, artificial intelligence, and molecular modeling, enabling the design of proteins with unprecedented precision and functionality. Computational methods now play a crucial role in enhancing the stability, activity, and specificity of proteins for diverse applications in biotechnology and medicine. Techniques such as deep learning, reinforcement learning, and transfer learning have dramatically improved protein structure prediction, optimization of binding affinities, and enzyme design.

Fabrication and evaluation of chitosan-coated nanostructured lipid carriers for co-delivery of paclitaxel and PD-L1 siRNA.

This study aimed to develop a nanostructured lipid carrier (NLC) capable of co-delivering paclitaxel (PTX) and programmed death-ligand 1 (PD-L1) small interfering RNA (siRNA) to enhance PTX bioavailability and bolster immunity through PD-L1 knockdown. We prepared a PTX-loaded NLC (P-NLC) and coated it with positively charged chitosan (Chi) to create P-NLC-Chi, which was subsequently conjugated to siRNA (P-NLC-Chi-siRNA). The P-NLC-Chi formulation was optimized using the Box-Behnken design.

Metamagnetic transition and meta-stable magnetic state in Co-doped FeGaTe.

The transition between the ferromagnetic (FM) and anti-ferromagnetic (AFM) phases in van der Waals (vdW) magnets has been extensively studied since the discovery of vdW magnets, due to the importance of both transitions within a single material. Recently, among vdW magnets, FeGaTe (FGaT) has garnered significant attention for its robust FM properties that remain stable above room temperature. Also, the FM to AFM phase transition in this material has been achieved through substitutional Co-atom doping at Fe sites.

Sex ratio and conception rates of fresh/vitrified embryos at different developmental stages by ovum pick up in Hanwoo cows.

Embryo transfer plays a crucial role in enhancing the breeding value of livestock; it has been applied in Hanwoo cattle, which is a popular breed for beef production in Korea. Both -derived (IVD) and -produced (IVP) embryos are used for this purpose; however, IVP embryos have been preferred recently owing to advancements in ovum pick-up (OPU) technology and genomic selection. Despite technological advancements, comprehensive data on large-scale OPU/IVEP/embryo transfer in Hanwoo cows are lacking.

Evaluation of conical 9 well dish on bovine oocyte maturation and subsequent embryonic development.

The Conical 9 well dish (C9 well dish) is characterized by a decreasing cross-sectional area towards the base. This design was hypothesized to enhance embryonic development by emulating the physical environment through density modulation. Comparative analyses revealed no significant difference in nuclear maturation rates between the C9 well dish and the 5-well dish.

Feeding dietary non-starch polysaccharides supplemented with xylanase could improve the performance of broilers.

The impact of dietary non-starch polysaccharides (NSP) on performance and carcass traits of broilers fed wheat-bran substituted into corn-soybean meal-based diets supplemented with xylanase was investigated. A total of 280 (7-day-old) Ross 308 broilers were randomly allotted to one of five dietary treatments with 8 replicates, 7 chicks per pen. Treatments were; i) CON: Control diet, ii) CON-X (CON + 3,000 U/kg xylanase), iii) L-X: low NSP (2% wheat bran in CON + 3,000 U/kg xylanase), iv) M-X: medium NSP (4% wheat bran in CON + 3,000 U/kg xylanase), v) H-X: higher NSP (8% wheat bran in CON+ 3,000 U/kg xylanase).

Effects of phytogenic feed additives in growing and finishing pigs under different stocking density.

This study was to investigate effects of different phytogenic feed additives (PFA) in grower finishing pigs with stressed by high stocking density. A total of 84 growing pigs ([Landrace × Yorkshire] × Duroc) with initial body weight (BW) of 28.23 ± 0.

Capsicum annuum NAC4 (CaNAC4) Is a Transcription Factor with Roles in Biotic and Abiotic Stresses.

Transcription factors (TFs) regulate gene expression by binding to DNA. The NAC gene family in plants consists of crucial TFs that influence plant development and stress responses. The whole genome of Capsicum annuum shows over 100 NAC genes (CaNAC).

Cestrum tomentosum L.f. Extracts against Colletotrichum scovillei by Altering Cell Membrane Permeability and Inducing ROS Accumulation.

Chili pepper anthracnose, caused by Colletotrichum spp., is a significant biotic stress affecting chili fruits globally. While fungicide application is commonly used for disease management due to its efficiency and costeffectiveness, excessive use poses risks to human health and the environment.