Effect of Stir-Frying, Boiling, and Baking on Hexaconazole Residue Levels in Welsh Onion ( L.).

Hexaconazole, a triazole insecticide, is widely used to control rust disease in Welsh onions. Residue levels of pesticides vary based on the cooking methods. Although studies on hexaconazole residue have involved vegetables such as cabbage, research on Welsh onion is limited.

Effectiveness of a blended (distance and in-person) simulation education program on advanced cardiac life support for nursing students using the PARTNER model.

Background: The incidence of acute cardiac arrest is increasing and is directly linked to patient survival, highlighting the critical role of nurses. Advanced nursing skills for cardiac arrest patients, such as self-directed pre-learning applied to various clinical situations, require a systematic blended learning approach to integrate knowledge and enhance clinical performance through face-to-face practice. The purpose of this study is to evaluate the effectiveness of a blended simulation education program for Advanced Cardiac Life Support (ACLS) using the PARTNER model.

The impact and transformation evaluation of art intervention in public space on ancient villages: a case study of Tengchong, Yunnan Province.

As the need for balancing cultural heritage preservation with economic development becomes increasingly urgent, the sustainable development of ancient villages has emerged as a critical issue. This study focuses on the ancient villages of Tengchong, Yunnan, to examine the profound impact of art intervention in public spaces on their development. Through literature review, QGIS analysis, questionnaire surveys, and hierarchical analysis, the study reveals that art intervention plays a pivotal role in enhancing the environmental appearance (0.

Modulatory roles of capsaicin on thermogenesis in C2C12 myoblasts and the skeletal muscle of mice.

Capsaicin, a polyphenol, is known to regulate energy expenditure and thermogenesis in adipocytes and muscles. However, its role in modulating uncoupling proteins (UCPs) and adenosine triphosphate (ATP)-dependent thermogenesis in muscles remains unclear. This study investigated the mechanisms underlying the role of capsaicin in modulating the UCP- and ATP-dependent thermogenesis in C2C12 myoblasts, as well as the gastrocnemius (GM) and soleus muscles (SM) of mice.

Review of Cathepsin K Inhibitor Development and the Potential Role of Phytochemicals.

Cathepsin K plays a pivotal role in bone resorption and has emerged as a prominent therapeutic target for treating bone-related diseases such as osteoporosis. Despite significant advances in synthetic inhibitor development, none have achieved FDA approval due to safety and efficacy challenges. This review highlights the potential of phytochemicals as alternative inhibitors, emphasizing their natural origin, structural diversity, and minimal adverse effects.

Exploring Voice Acoustic Features Associated with Cognitive Status in Korean Speakers: A Preliminary Machine Learning Study.

: To develop a non-invasive cognitive impairment detection system using speech data analysis, addressing the growing global dementia crisis and enabling accessible early screening through daily health monitoring. : Speech data from 223 Korean patients were collected across eight tasks. Patients were classified based on Korean Mini-Mental State Examination scores.

MetAP2 as a Therapeutic Target for Obesity and Type 2 Diabetes: Structural Insights, Mechanistic Roles, and Inhibitor Development.

Type 2 Diabetes Mellitus (T2DM) and obesity are globally prevalent metabolic disorders characterized by insulin resistance, impaired glucose metabolism, and excessive adiposity. Methionine aminopeptidase 2 (MetAP2), an intracellular metalloprotease, has emerged as a promising therapeutic target due to its critical role in regulating lipid metabolism, energy balance, and protein synthesis. This review provides a comprehensive analysis of MetAP2, including its structural characteristics, catalytic mechanism, and functional roles in the pathophysiology of T2DM and obesity.

Development and Validation of the COVID-19 Infection Fear Scale in a Collectivist Cultural Context: A Study From South Korea.

Objective: Understanding the specific fears associated with coronavirus disease-2019 (COVID-19), particularly within different cultural contexts, is crucial for developing effective mental health interventions. This study aims to develop and validate the COVID-19 Infection Fear Scale (CIFS) in a collectivist cultural context such as Korea.

Methods: A total of 1,002 adults aged 19 to 70 participated in an online survey in May 2020.

A spatially-heterogeneous impact of fencing on the African swine fever wavefront in the Korean wild boar population.

In October 2019, South Korea's first case of African swine fever (ASF) was reported in wild boar in the north of the country. Despite the implementation of a 2300 km-long fencing strategy, the ASF wavefront continued to invade southward. Our study aimed to investigate the ASF wavefront dynamics in different regions of South Korea, as well as to assess the effectiveness of the fencing measures on ASF dispersal and wavefront velocity.

Emotional Touch Nursing Competencies Model of the Fourth Industrial Revolution: Instrument Validation Study.

Background: The Fourth Industrial Revolution is transforming the health care sector through advanced technologies such as artificial intelligence, the Internet of Things, and big data, leading to new expectations for rapid and accurate treatment. While the integration of technology in nursing tasks is on the rise, there remains a critical need to balance technological efficiency with empathy and emotional connection. This study aims to develop and validate a competency model for emotional touch nursing that responds to the evolving demands of the changing health care environment.

Sulfur powder utilization and denitrification efficiency in an elemental sulfur-based membrane bioreactor with coagulant addition.

The integration of elemental sulfur-based autotrophic denitrification with membrane bioreactor (MBR) technology offers a cost-effective solution for nitrate removal; however, stable operation demands efficient sulfur utilization and phosphorus management. This study explores sulfur consumption dynamics and the impacts of coagulant injection on denitrification efficiency. Sulfur consumption was closely correlated with nitrate removal rates, highlighting the critical role of stoichiometric sulfur availability for sustained denitrification.

Understanding Grandparent Caregiving in Korean and U.S. Culture: An Analysis Using Role Theory.

This study explored grandparent caregiving experiences in Korea and the United States. Using a phenomenological approach, semi-structured interviews were conducted with 20 custodial grandparents (10 in Korea, 10 in the United States) to understand their lived experiences. Under the guidance of role theory, the caregivers' experiences were explained by themes of role consensus, role conformity, and role conflict.

Anti-Cancer Effect of Sulforaphane in Human Pancreatic Cancer Cells Mia PaCa-2.

Background: Pancreatic cancer is difficult to treat early as it has no early symptoms. The presence of sulforaphane (SFN) in cruciferous vegetables has been found to possess anti-cancer effects in gastric and colon cancers. Glycogen synthase kinase-3 beta (GSK-3β), a serine/threonine kinase, plays a significant role in pancreatic cancer progression, influencing tumor growth, metastasis, and treatment resistance.

A comprehensive pyrolysis-gas chromatography/mass spectrometry analysis for the assessment of microplastics in various salts.

Analytical pyrolysis-gas chromatography/mass spectrometry(Py-GC/MS) was chosen to quantify microplastics(MPs) in edible salts: sea salt(SS), deep-sea salt(DSS), rock salt(RS), and lake salt(LS). Samples were filtered by two-step using 20 μm(MPs20) and 1 μm(MPs1) filters. Two Py-GC/MS methods with split ratios of 100/1 for high-level and 10/1 for low-level MPs were used.

Spontaneous detection of F and viscosity using a multifunctional tetraphenylethene-lepidine probe: Exploring environmental applications.

Excessive fluoride ions (F) in drinking water and food is harmful for human health and the environment. Therefore, a fluorescent probe tetraphenylethylene-quinoline (P-1) is developed with multiple sensing properties for the sequential detection of tert-butyldiphenylsilyl chloride (TBDS), F, and viscosity. Sensor P-1 first recognized TBDS and then observed an intramolecular charge transfer process, which produced an intermediate sensor P-2 in addition to fluorescence quenching at 576 nm.

Assessment of Digestion and Absorption Properties of 1,3-Dipalmitoyl-2-Oleoyl Glycerol-Rich Lipids Using an In Vitro Gastrointestinal Digestion and Caco-2 Cell-Mediated Coupled Model.

The digestion and absorption properties of 1,3-dipalmitoyl-2-oleoyl glycerol (POP)-rich lipids was evaluated using in vitro gastrointestinal digestion and a Caco-2 cell-mediated coupled model. Caco-2 cell viability and monolayer integrity were assessed by an MTT assay and transepithelial electrical resistance. The IC50 for bile salts, pancreatin, and free fatty acid (FFA) were 0.

Distribution of Dietary Phospholipids in Selected Agri-Foods: Versatile Nutraceutical Ingredients.

Phospholipids (PLs) play a crucial role in the nutraceutical field due to their various health benefits, including supporting acetylcholine production, enhancing cell membrane fluidity, and promoting cognitive functions. This study aimed to investigate the PL composition of selected agri-foods, including grains, vegetables, and fruits, and assess the effects of cooking methods. The major PLs identified in most agri-foods were phosphatidylethanolamine (PE) and phosphatidylcholine (PC).

A seventeen-year, population-based study to identify dynamic patterns of interfering neck pain and its burden in South Korea.

Aim: The aim of this study were to introduce a profile of a nationwide cohort for patients with neck pain and to identify the patterns of recurrent neck pain over time.

Methods: Health insurance data for 1,127,323 patients (43.5 ± 11.

The role of MELK in cancer and its interactions with non-coding RNAs: Implications for therapeutic strategies.

In the evolving landscape of cancer research, the identification of key molecular players that contribute to the disease's progression and resistance against treatments has become paramount. Among these, Maternal Embryonic Leucine Zipper Kinase (MELK) has emerged as a critical regulator of cancer cell proliferation, survival, and therapy evasion. Concurrently, the significance of non-coding RNAs (ncRNAs), including microRNAs (miRNAs) and long non-coding RNAs (lncRNAs), in modulating gene expression and cancer phenotypes has been increasingly recognized.

Application and renovation evaluation of Dalian's industrial architectural heritage based on AHP and AIGC.

This paper takes the example of industrial architectural heritage in Dalian to explore design scheme generation methods based on generative artificial intelligence (AIGC). The study compares the design effects of three different tools using the Analytic Hierarchy Process (AHP). It first establishes the key indicator weights for the renovation of industrial architectural heritage, with the criterion layer weights as follows: building renovation 0.

Wildlife-Vehicle Collisions and Mitigation: Current Status and Factor Analysis in South Korea.

Severe habitat loss and fragmentation due to extensive road development have escalated wildlife-vehicle collisions (WVCs) as one of the major causes of wildlife mortality. This study, spanning 9 years from 2009 to 2017, presents comprehensive WVC data in South Korea, including species composition, seasonal and regional patterns, and road factors influencing WVCs, aiming to analyze their impact and propose effective mitigation strategies. We collected WVC data with road variables for 9 years from 4561 km of nationwide monitoring road sections and analyzed the data to understand the relationship between WVCs and road characteristics, as well as species-specific patterns.