Dietary Modification as a Part of Prescription in Inflammatory Lesions of Oral Cavity: A Need of the Hour.

Food is an integral aspect of human life and constitutes major portion of the intake on a daily basis. The dietary patterns are highly distinctive not only for any religion but also for geographic locations. Even a particular geographic location might show vast distinctiveness in terms of consumption of food on a day-to-day basis.

Similarity Index Analysis of the Manuscript: A Viewpoint.

Fabrication, falsification, and plagiarism have been considered the major academic/scientific misconduct in writing the research.1 In recent decades, plagiarism detection has become relatively easy with the evolution of newer software.2,3 Undoubtedly, many scientific journals evaluate the received manuscripts for plagiarism/similarity index and strictly refuse to consider manuscripts with higher similarity index for further publication process.

A Critical Appraisal on the "Level-of-evidence" Classification Systems.

Evidence-based medicine is about analyzing the evidence and then utilizing the same analysis in making clinical decisions. The key element of evidence-based medicine is the hierarchical system of categorizing evidence. This hierarchy is known as the "levels of evidence".

Pyroptosis and Oral Cancer.

Cell death is a basic biological occurrence which is required for the existence and growth of an organism. Programmed cell death sustains tissue homeostasis facilitating the elimination of redundant cells. When an infectious disease sets in, cells that have been infected by pathogens prove harmful to the host eclls.

Pediatricians' Self-Efficacy Affects Frequency of Giving Oral Health Advice, Conducting Oral Examination, and Prescribing Referrals.

To assess the role of pediatricians' self-efficacy on frequency of enquiring about dental visits, conducting oral examinations, and prescription of referrals to dentists.
Pediatricians and pediatric medicine residents in public hospitals in Singapore completed a self-administered written questionnaire between April and October 2015. Participants' demographics, training, knowledge of oral health, perceived importance of oral health, and confidence in health-promoting behaviors were assessed.

Histomorphological Evidence of Cellular Cannibalism in Ameloblastoma.

Aim: To study the cellular cannibalism (CC) in the tumor cells of ameloblastoma.

Materials And Methods: Hematoxylin and eosin (HE)-stained sections of ameloblastoma cases (50) were retrieved from the archived specimens and screened for cellular cannibalism (CC) by stellate reticulum-like cells. Further characterization of CC was performed using CD68 and lysozyme antibodies.

Prosthetic Rehabilitation of Microstomia Patients: A Systematic Review of Published Case Reports and Case Series.

Statement Of Problem: Prosthetic techniques commonly employed for the rehabilitation of edentulous patients might not be adequate in the treatment of patients with microstomia.

Purpose: The purpose of this paper is to systematically review all the prosthetic techniques that have been used in the oral rehabilitation of patients with microstomia.

Materials And Methods: Data sources, including PubMed, Google Scholar, SCOPUS and Web of Science, were searched for case reports and case series published through September 2017.

Use of Tilapia Hepcidin in Oral Cancer Therapeutics: A Proposal.

Tilapia hepcidin (TH), an antimicrobial peptide (AMP) derived from tilapia () forms an important component of the fish innate immune defense. However, the functionality of TH is not just limited to its antimicrobial actions, significant applications in cancer research remain an area to be explored. Antimicrobial peptides derived from fish and shrimp demonstrated anticancer activities in addition to their previously discovered antimicrobial action.

Use of X-ray Diffraction Technique of Hair for Oral Cancer Detection: A Proposal.

Techniques that contribute to early diagnosis of oral potentially malignant disorders (OPMDs) and oral squamous cell carcinoma (OSCC) till now followed are vital staining, light-based detection systems along with various histological, cytological, molecular and imaging techniques. In spite of histopathological technique being the gold standard, diagnosis by taking random biopsies of both clinically normal and the suspected oral area is impractical, since various serious downsides are associated with it and are also not appropriate for repetitive sampling at multiple sites. A screening test which is non-invasive, safe without exposing an individual to X-radiation and more consistent than any other current method is direly required.

Effect of Formalin Fixation on Surgical Margins in Patients With Oral Squamous Cell Carcinoma.

Purpose: Formalin fixation causes shrinkage of surgical margins, which can result in the underestimation of tumor-free margins. The purpose of this study was to show the effect of formalin fixation on surgical margins. Another aim of this study was to evaluate surgical margin shrinkage after fixation of oral squamous cell carcinoma (OSCC) specimens of the gingivobuccal sulcus (GBS).

Inventory Analysis in a Private Dental Hospital in Bangalore, India.

Introduction: There are various approaches for inventory management. Of all the inventory control systems, ABC (Always, Better, Control) and VED (Vital, Essential, Desirable) matrix is most suitable for dental stores. We could not find any literature pertaining to inventory analysis in a private dental hospital.

Techniques to Evaluate Dental Erosion: A Systematic Review of Literature.

This article reviews different techniques for evaluating dental erosion, weighs the advantages and disadvantages of these techniques, and presents the latest trends in the study of dental erosion. In May 2014, an initial search was carried out in the PubMed/MEDLINE database of indexed journals from 1975 to 2013 using the following keywords: dental erosion; dental erosion In-vitro; and dental erosion in-vivo. Bibliographic citations from the papers found were then used to find other useful sources.

Bipartite Task of Immunity in Cancer Progression.

The spontaneous regression and remission from malignancy was defined by Everson and Cole as "the partial or complete disappearance of a malignant tumor in the absence of all treatment, or in the presence of therapy which is considered inadequate to exert significant influence on neoplastic disease."

Messenger Services on Smartphone: Changing Trends of Communication in Dental Practice.

A smartphone has become an integral part of human life. It is estimated that there will be 200 million smartphone users in India by the end of 2016 and India will become the second largest smartphone market in the world.(1) Accordingly, Internet use on mobile has also flourished extraordinarily, and by the end of 2017, there will be 314 million Internet users in India.

Junk DNA: Prospects for Oral Cancer Research.

About 98% of human genes are transcribed into noncoding ribonucleic acid (RNA), which is known by the name of "junk DNA." Unlike its name, it has been proved by now that junk deoxyribonucleic acid (DNA) can have some functional activities.

Bioimpedance Assessment of Oral Squamous Cell Carcinoma with Clinicopathological Correlation.

Aim: Molecular alterations at membrane, cytosol and nuclear level in cancer cells/tissue show variations in bioimpedance measure. In the present study, bioimpedance assessment and comparison was investigated between oral squamous cell carcinoma (OSCC) and normal tissue. Study further involves clinicopathological correlation of bioimpedance values in OSCC.

Inflammation and Oral Cancer: An Update Review on Targeted Therapies.

In the recent past, numerous inflammation-mediated molecular pathways have been explored and studied as important events in carcinogenesis with respect to oral squamous cell carcinoma (OSCC). These pathways are engaged in numerous stages during tumorigenesis; which includes processes, like initiation, promotion, malignant conversion, invasion and metastasis. The inflammation-mediated/related carcinogenesis pathways reported in OSCC involves COX-2, epidermal growth factor receptor (EGFR), p38a MAP kinase, NF-kB, STAT, RhoC, PPARy, etc.

Comparative evaluation and correlation of salivary total antioxidant capacity and salivary pH in caries-free and severe early childhood caries children.

Background: Dental caries is a major problem in preschool children. The contribution of saliva in providing defense during caries process is of primary importance. pH buffer capacity through bicarbonate, phosphate and protein buffer systems have universal acceptance as a caries defense mechanism.

The effect of alloplastic bone graft and absorbable gelatin sponge in prevention of periodontal defects on the distal aspect of mandibular second molars, after surgical removal of impacted mandibular third molar: a comparative prospective study.

Aim: Recent studies claim that haemostatic agents can be used as bone graft substitutes. The aim of this study was to compare the efficacy of alloplastic bone graft with absorbable gelatin sponge in prevention of periodontal defects distal to mandibular second molar after the surgical removal of impacted mandibular third molars.

Materials And Methods: A prospective, randomized, single-blind split-mouth study was designed.

MicroRNA in oral cancer research: future prospects.

MicroRNA (miRNA) and related therapeutic approaches hold great promise in the field of cancer managements. Various studies on epithelial malignancies have shown encouraging results on various fronts. Its association with invasion, tumor growth, epithelial mesenchymal transition (EMT), angiogenesis, cancer stem cells (CSCs), metastasis and refects the diversified role of miRNA.

Pseudomembranous Type of Oral Candidiasis is Associated with Decreased Salivary Flow Rate and Secretory Immunoglobulin A Levels.

Saliva plays an important role in maintaining microbial homeostasis in the oral cavity, while salivary gland hypofunction predisposes the oral mucosa to pathologic alteration and increases the risk for oral candidiasis. This study sought to determine the salivary flow rate (SFR) and secretory immunoglobulin A (SIgA) levels in HIV-positive and HIV-negative individuals and evaluate their relationship with the determinants of oral candidiasis. Sixty HIV-positive (30 with and 30 without oral candidiasis) and 30 healthy HIV-negative individuals were enrolled.

Inherited Oral Cancer: A Rare Reality.

Majority of oral cancers (around 90-95%) found today are caused by various environmental factors. These generally include the chemical and physical carcinogens, like tobacco, diet, microorganisms, radiations, etc. The remaining 5% of the cases are caused by inherited mutated genes carrying the defect.

ABO blood groups and oral premalignancies: A clinical study in selected Indian population.

Background: The ABO blood group antigens are present on the surface of red blood cells and various epithelial cells. As the majority of human cancers are derived from epithelial cells, changes in blood group antigens constitute an important aspect of human cancers. The aim of the study was to establish clinical usefulness of ABO blood group as a predisposing factor in early diagnosis and management of patients with oral precancerous lesions/conditions.

The comparative evaluation of the effects of tongue cleaning on existing plaque levels in children.

The present study compared and evaluated the effects of tongue scraping and tongue brushing on existing plaque levels in children. The investigation was a single blind, stratified comparison of three parallel groups of children who performed either tongue scraping or tongue brushing along with tooth brushing or only tooth brushing twice daily under professional supervision for a 21 day period. Dental plaque was recorded using the plaque index described by Silness and Loe at baseline, on day 10 and on day 21.