Physiological monitoring of movement and manoeuvrability during a military skiing exercise.

Introduction: Military forces receive training in various high-altitude warfare techniques to safeguard border regions and lives. Skiing is one of such practices where research evidences are limited. Therefore, a study was conducted to continuously monitor the physiological status of soldiers during military skiing practice to quantify the actual demands.

Hypoxia related genes modulate in similar fashion in skin fibroblast cells of yak (Bos grunniens) adapted to high altitude and native cows (Bos indicus) adapted to tropical climate during hypoxia stress.

The present study was conducted to understand transcriptional response of skin fibroblast of yak (Bos grunniens) and cows of Bos indicus origin to hypoxia stress. Six primary fibroblast cell lines derived from three individuals each of Ladakhi yak (Bos grunniens) and Sahiwal cows (Bos indicus) were exposed to low oxygen concentration for a period of 24 h, 48 h and 72 h. The expression of 10 important genes known to regulate hypoxia response such as HIF1A, VEGFA, EPAS1, ATP1A1, GLUT1, HMOX1, ECE1, TNF-A, GPx and SOD were evaluated in fibroblast cells of Ladakhi yak (LAY-Fb) and Sahiwal cows (SAC-Fb) during pre- and post-hypoxia stress.

Physiological benefits of Akkermansia muciniphila under high-altitude hypoxia.

When sojourners visit to high altitude, various symptoms may appear in the body including gastrointestinal symptoms such as poor appetite or nausea, vomiting, and incapacitating. The gastrointestinal tract is a key organ involved in the development of acute mountain sickness (AMS). The intestinal epithelial lining is covered by mucus layer.

Quantification of physiological and mental workloads of faster and slower finishers of a long-distance military training activity.

Background: Long-distance runs with equipment are practised in military training establishments to develop physical stamina and prepare for battles. A study was planned to quantify and compare the physiological and mental workloads of the early and late finishers of a military endurance run through the jungle terrain of north-eastern India in hot and humid conditions.

Methods: Twenty-five soldiers of the Indian Army completed a 15 km run through a rural and jungle track with 6.

Health Risk Assessment of Heavy Metals Due to Wheat, Cabbage, and Spinach Consumption at Cold-Arid High Altitude Region.

Soil and water from the trans-Himalayan high-altitude region contain high concentrations of various heavy metals. Vegetables and cereals such as cabbage, spinach, and wheat are most prone to heavy metal accumulation from soil and water which can be toxic for human consumption. It has yet to be studied how consumption of vegetables and cereal with excess heavy metal content can affect human health in high altitude areas.

Health Risk Assessment of Heavy Metals Through Cow Milk Consumption in Trans-Himalayan High-Altitude Region.

Consumption of heavy metals contaminated dairy milk may affect human health. No such studies have been carried out at the high-altitude region to assess the human health risk after consuming dairy milk. To this end, this study reveals the evaluation of selected heavy metals in dairy milk in the summer and winter seasons, followed by the assessment of heavy metals health risk.

Ursolic acid ameliorates hypobaric hypoxia-induced skeletal muscle protein loss via upregulating Akt pathway: An experimental study using rat model.

Hypobaric hypoxic stress leads to oxidative stress, inflammation, and disturbance in protein turnover rate. Aggregately, this imbalance in redox homeostasis is responsible for skeletal muscle protein loss and a decline in physical performance. Hence, an urgent medical need is required to ameliorate skeletal muscle protein loss.