1 results match your criteria: "DIFACQUIM Research Group Department of Pharmacy School of Chemistry[Affiliation]"
Diversity and Chemical Space Characterization of Inhibitors of the Epigenetic Target G9a: A Chemoinformatics Approach.
ACS Omega
August 2023
DIFACQUIM Research Group Department of Pharmacy School of Chemistry, Universidad Nacional Autónoma de México, Mexico City 04510, Mexico.
G9a is a histone-lysine methyltransferase that performs the mono- and dimethylation of lysine 9 at histone 3 of the nucleosome. It belongs to the SET PKMT family, and its methylations are related to promoter repression and activation. G9a is a promising epigenetic target.
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