FRAX-Based Intervention Thresholds for Osteoporosis Treatment in Ukraine.

Objectives: Osteoporosis, in addition to its consequent fracture burden, is a common and costly condition. FRAX is a well-established, validated, web-based tool which calculates the 10-year probability of fragility fractures. A FRAX model for Ukraine has been available since 2016 but its output has not yet been translated into intervention thresholds for the treatment of osteoporosis in Ukraine; we aimed to address this unmet need in this analysis.

FEATURES OF BONE METABOLISM AND THEIR INFLUENCE ON ARTERIAL WALL STIFFNESS IN POSTMENOPAUSAL WOMEN WITH CONTROLLED UNCOMPLICATED HYPERTENSION.

The aim of this study was to investigate the features of bone metabolism and their influence on the arterial wall stiffness in postmenopausal women with a controlled uncomplicated arterial hypertension (AH). The study involved 44 women (main group) with the mean age of 69.04±0.

Epigenetic enzymes: A role in aging and prospects for pharmacological targeting.

The development of interventions aimed at improving healthspan is one of the priority tasks for the academic and public health authorities. It is also the main objective of a novel branch in biogerontological research, geroscience. According to the geroscience concept, targeting aging is an effective way to combat age-related disorders.

[Vertebral pain syndrome and quality of life in senior women with vertebral fractures depending on their quantity and localization.].

The features of vertebral pain (VP) and quality of life in postmenopausal women were analyzed depending on the number and location of vertebral fractures (VF). It was found that the intensity of pain in thoracic and lumbar spines, according to McGill pain index, was significantly higher in patients with two or more VF compared to women without any fractures, and absence of differences in subjects with a single VF. Most indices of 11-component Numerical Rating Scale at the thoracic spine were significantly higher only in females with two or more VF.

Bone Mineral Density and Risk of Osteoporotic Fractures in Women with Parkinson's Disease.

Osteoporosis and Parkinson's disease (PD) are two important age-related diseases, which have an influence on pain, physical activity, disability, and mortality. The aim of this research was to study the parameters of bone mineral density (BMD), frequency, and 10-year probability of osteoporotic fractures (OFs) in females with Parkinson's disease (PD). We have examined 113 postmenopausal women aged 50-74 years old which were divided into 2 groups (I, control group (CG),  = 53 and II, subjects with PD,  = 60).

Calcium intake in an adult Ukrainian population.

Unlabelled: This is a first large epidemiological study of calcium intake in Ukrainian population. The data from 1518 outpatient subjects aged 20-89 years old showed that the mean level of calcium intake composed 615.6 mg/day (735.

Bone Mineral Density, TBS, and Body Composition Indexes in Ukrainian Men with Parkinson's Disease.

Introduction: Current research studies demonstrate the changes of bone mineral density (BMD) in subjects with Parkinson's disease (PD); however, data about bone quality and body composition (BC) indexes are insufficient. The aim of the study was to assess the parameters of BMD, ВС, and trabecular bone score (TBS) in PD males.

Materials And Methods: We performed a cross-sectional case-control research design and examined 76 males aged 50-77 years old, who were divided into two groups: first group including men without PD (=38) and the second group including subjects with PD (=38).