[Features of chromosome segregation in unfertilized human oocytes].

Mechanisms of abnormal chromosomal segregation in female meiosis and factors exerting influence on unfertilized human oocytes have been analysed in vitro. The differences in results of cytological studies on the rate of aneuploidy have been reviewed. The advanced maternal age is primarily associated with disturbances in oocyte meiosis.

[Effect of concentration of spermatozoids on fertilization of oocytes and human embryo development in vitro].

The correlation between sperm insemination concentrations, rates of normal and abnormal fertilization and embryo development was investigated. For male factor patients fertilization rates are significantly lower than for female factor. We have found the increased fertilization rate for male factor, if insemination concentration increased from 10 x 10(4) to 15 x 10(4) per 1 ml.

[Relationship between the frequency of cultured oocytes fertilization and morphology of human sperm].

The study has evaluated 304 cases under of vitro fertilization. Positive correlations were shown of semen parameters and fertilization rate. The individual spectrum of different sperm morphological types was shown to be constant.