5 results match your criteria: "Dışkapı Yıldırım Bayezit Training and Research Hospital[Affiliation]"

Objectives: The aim of the present study was to assess thiol/disulfide (SS) homeostasis as a novel indicator of oxidative stress in patients with obstructive sleep apnea (OSA) and to investigate the effect of continuous positive airway pressure (CPAP) therapy on oxidative parameters.

Study Design: Prospective clinical study.

Methods: A total of 104 subjects, 44 in an OSA group and 60 in two control groups (control simple snoring group, control OSA group) were included.

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Objectives: To investigate a novel oxidative stress marker, thiol/disulphide literature homeostasis, in patients with idiopathic sudden sensorineural hearing loss, and to compare the results with healthy controls for the first time.

Methods: Thirty-two patients with idiopathic sudden sensorineural hearing loss and 30 healthy individuals were included in the study. Serum native thiol, total thiol and disulphide levels were measured, and disulphide/native thiol and disulphide/total thiol ratios were determined in all subjects.

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Purpose: To investigate the association between metabolic syndrome and prostate cancer risk in Turkish men.

Methods: We examined data from 220 patients with prostate cancer and 234 men in a control group with benign biopsy results, who had a serum prostate-specific antigen (PSA) level ⩾ 4 ng/ml, or an abnormal digital rectal examination finding and who underwent transrectal ultrasound-guided prostate biopsy at two main training and research hospitals between February 2009 and April 2013. Metabolic syndrome was diagnosed according to The Society of Endocrinology and Metabolism of Turkey metabolic-syndrome criteria.

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Article Synopsis
  • The discrepancy between Gleason scores from prostate biopsies and prostatectomies is a common issue; this study aims to identify predictive features in biopsies for GS upgrading in patients with scores ≤6 who undergo radical retropubic prostatectomy.
  • A retrospective analysis of 321 men showed that 40.8% experienced GS upgrading, with significant predictors being prostate volume <40 cc, a higher percentage of cancer in any biopsy core, and having more than one core positive for cancer.
  • The findings suggest that patients with small prostates and multiple positive biopsy cores should receive thorough counseling regarding treatment options due to their increased risk of upgrading.
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