detachment from linoleum surface: influence of liquid flow rate and cleaner type.

The aim of this research is to analyse the impact of surface cleaner type and hydrodynamic flow on bacterial detachment. For that purpose, a new liquid flow chamber was constructed and applied. In experiments, was grown on linoleum surfaces that are used in health care institutions.

Innovative antimicrobial lignins: Extraction and characterization for advanced hydrogel applications.

The antioxidant and antimicrobial activities of lignin are often emphasized; however, not every type exhibits these properties. In this work, water-soluble fractions of alkali lignin (AL), poly-(caffeyl alcohol) lignin (PCFA), pyrolytic lignin (PL) and grape seed lignin (GSL) were prepared. The original and water-soluble lignin fractions were comprehensively characterized using high-resolution 2D NMR spectroscopy.

Pharmacokinetics of the systemic application of hyaluronic acid for joint arthritis treatment.

Frequent degenerative joint diseases, known as arthritis, are characterized by joint inflammation and cartilage breakdown. Various arthritis types are traditionally managed with intra-articular injections of hyaluronan or its derivatives. However, intravenous administration of hyaluronan is emerging as a vital alternative, particularly because intra-articular injections can be challenging for clinicians when targeting small or swollen joints.

Anti-Cancer Potential of a new Derivative of Caffeic Acid Phenethyl Ester targeting the Centrosome.

Anaplastic Large Cell Lymphoma (ALCL) is an aggressive T-cell lymphoma affecting children and young adults. About 30% of patients develop therapy resistance therefore new precision medicine drugs are highly warranted. Multiple rounds of structure-activity optimization of Caffeic Acid Phenethyl Ester have resulted in CM14.

Disgust sensitivity in the first trimester predicts anxiety levels in advanced pregnancy.

Problem: Disgust contributes to anxiety-based psychopathology, and in turn, anxiety increases disgust proneness.

Background: Disgust and anxiety undergo significant changes in pregnancy, but no previous study has examined their longitudinal associations in this time period.

Aim: This prospective longitudinal study aimed to identify longitudinal associations between disgust sensitivity and state anxiety across the three trimesters of pregnancy, while exploring the directionality of the effect between those two variables.

Significant Tumor Inhibition of Trimethyl-152-[L-aspartyl]pheophorbide a in Tumor Photodynamic Therapy‡.

A novel pheophorbide derivative, trimethyl-152-[L-aspartyl]pheophorbide a was synthesised and investigated for anti-tumor activity. The prepared photosensitizer had good absorption in the phototherapeutic window and high ROS yields. It exhibited excellent phototoxicity higher than reference compound m-THPC when irradiated by 650 nm light in vitro, and obvious photodynamic anti-tumor effect in vivo.

Using normative models pre-trained on cross-sectional data to evaluate intra-individual longitudinal changes in neuroimaging data.

Longitudinal neuroimaging studies offer valuable insight into brain development, ageing, and disease progression over time. However, prevailing analytical approaches rooted in our understanding of population variation are primarily tailored for cross-sectional studies. To fully leverage the potential of longitudinal neuroimaging, we need methodologies that account for the complex interplay between population variation and individual dynamics.

Cerebellocerebral connectivity predicts body mass index: a new open-source Python-based framework for connectome-based predictive modeling.

Background: The cerebellum is one of the major central nervous structures consistently altered in obesity. Its role in higher cognitive function, parts of which are affected by obesity, is mediated through projections to and from the cerebral cortex. We therefore investigated the relationship between body mass index (BMI) and cerebellocerebral connectivity.

In memoriam: Carl J. Carrano : July 14, 1950-January 26, 2022.

This article is a celebration of the life and work of Carl J. Carrano who, from a childhood in Long Island, New York, built a career in bioinorganic chemistry, especially in the context of metal uptake and halogen metabolism in microbes and marine organisms.

Preserving the Biologically Coherent Generic Concept of , 'Plant Destroyer'.

is a long-established, well known and globally important genus of plant pathogens. Phylogenetic evidence has shown that the biologically distinct, obligate biotrophic downy mildews evolved from at least twice. Since, cladistically, this renders 'paraphyletic', it has been proposed that evolutionary clades be split into multiple genera (Runge et al.

Selective Carbon Dioxide Hydrogenation to Olefin-Rich Hydrocarbons by Cu/FeOx Nanoarchitectures Under Atmospheric Pressure.

The conversion of carbon dioxide into fuels and fine chemicals is a highly desirable route for mitigating flue gas emissions. However, achieving selectivity toward olefins remains challenging and typically requires high temperatures and pressures. Herein, we address this challenge using 12 nm copper nanoparticles supported on FeOx micro-rods, which promote the selective hydrogenation of CO to light olefins (C-C) under atmospheric pressure.

Podocyte A20/TNFAIP3 Controls Glomerulonephritis Severity via the Regulation of Inflammatory Responses and Effects on the Cytoskeleton.

A20/Tnfaip3, an early NF-κB response gene and key negative regulator of NF-κB signaling, suppresses proinflammatory responses. Its ubiquitinase and deubiquitinase activities mediate proteasomal degradation within the NF-κB pathway. This study investigated the involvement of A20 signaling alterations in podocytes in the development of kidney injury.

Less reactogenic whole-cell pertussis vaccine confers protection from infection.

Pertussis resurged over the last decade in most countries that replaced the traditional whole-cell pertussis vaccines (wP) by the less reactogenic acellular pertussis vaccines (aP). The aP vaccines induce a Th2-polarized immune response and by a yet unknown mechanism hamper the clearance of from infected nasopharyngeal mucosa. The aP-induced pertussis toxin-neutralizing antibodies effectively prevent the life-threatening pertussis pneumonia in infants, but aP-elicited immunity fails to prevent infection of nasopharyngeal mucosa and transmission of .

'I couldn't live without hope': A qualitative study using reflexive thematic analysis on approaches to hope and prognostic awareness among people with advanced disease.

Background: Hope plays a pivotal role in enhancing the quality of life and coping strategies of individuals living with advanced diseases. The nature of the relationship between hope and prognostic awareness is unclear.

Aim: To explore the experiences and meanings of hope and their association with prognostic awareness among people with advanced incurable diseases.

Extent of surgical repair and outcomes after surgery for type A aortic dissection.

Background: Acute Stanford type A aortic dissection is a severe emergency condition that, if left untreated, is associated with a high mortality rate. The extent of surgical repair may impact the outcomes of these patients.

Method: Patients operated for acute type A aortic dissection from a multicentre European registry were included.

Preparation of a potentially synbiotic dairy product fortified with galactooligosaccharides.

We assessed the chemical, microbiological, rheological and sensory parameters of a fermented dairy product (FDP) containing a galactooligosaccharide (GOS) preparation. This was made from a solution of dried whey and skim milk containing 25% (w/w) lactose using a new enzyme with high transgalactosylation activity (Nurica: Danisco A/S). Conversion of the high initial lactose content enabled a good yield of 56% GOS to be achieved.

Reflections on the Potential and Risks of AI for Scientific Article Writing after the AI Endorsement by Some Scientific Publishers: Focusing on Scopus AI.

The introduction of ChatGPT3 in 2023 disrupted the field of artificial intelligence (AI). ChatGPT uses large language models (LLMs) but has no access to copyrighted material including scientific articles and books. This review is limited by the lack of access to: (1) prior peer-reviewed articles and (2) proprietary information owned by the companies.

Verbal encouragement in coaching: enhancing small-sided game performance in youth basketball players.

Background: Verbal coach encouragement is a key motivational strategy that enhances skill development, game strategy execution, and team cohesion. In youth basketball, where players are still developing technical and decision-making abilities, coach encouragement can play a crucial role in sustaining effort, improving focus, and fostering resilience under small-sided games (SSGs). This study investigated how coach encouragement (CE) influences young basketball players' technical performance and psychophysiological responses during competitive gameplay.

Jurassic Park approached: a coccid from Kimmeridgian cheirolepidiacean Aintourine Lebanese amber.

With the exception of a fly and a mite from the Triassic of Italy, all Mesozoic amber arthropods are from the Cretaceous. Late Jurassic Lebanese amber from Aintourine revealed a completely preserved adult coccid male (wing length 0.8 mm), gen.

Serum drug levels and medication adherence in heart failure: A comparative cohort analysis.

Objective: To determine changes in medication adherence in two cohorts of heart failure patients differing by year of data collection and using a direct method of adherence detection - serum drug level testing.

Methods: We added a second cohort of patients to a prospective monocentric registry of chronic heart failure patients (LEVEL-CHF registry). The two cohorts share the same inclusion criteria but differ by the year of enrolment (2018 and 2020).

Cutaneous Hemangioma With Epithelioid Features Harboring TPM3/4::ALK Fusions: A Distinct Entity or a Molecular Variant of Epithelioid Hemangioma?

Vascular neoplasms with epithelioid cytomorphology encompass a wide spectrum of benign and malignant lesions, including epithelioid hemangioma (EH), cutaneous epithelioid angiomatous nodule (CEAN), epithelioid hemangioendothelioma (EHE), and epithelioid angiosarcoma (EAS). Recently, the first case of a cutaneous hemangioma with epithelioid features harboring a TPM3::ALK fusion was reported. Herein, we report 4 additional cases, including 1 case with an alternate TPM4::ALK fusion, and expand on the clinicopathologic and molecular genetic features of these unusual vascular lesions.

Efficacy of human papillomavirus vaccines in the prevention of male genital diseases: a systematic review.

Objectives: To evaluate the results of randomised controlled trials (RCTs) regarding the efficacy of human papillomavirus (HPV) vaccination in preventing male genital-related diseases.

Methods: A systematic search of English language literature using PubMed, Scopus, and Cochrane Library was performed in April 2024 according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) protocol.

Results: Evidence from four RCTs (including 7008 male participants) support the efficacy of the quadrivalent HPV vaccine in preventing genital warts and persistent HPV infection in HPV-naïve men.

Evaluating Perinatal Health in Europe: A Comparison of Routine Population Birth Data Sources.

Background: International comparisons of population birth data provide essential benchmarks for evaluating perinatal health policies.

Objectives: This study aimed to describe routine national data sources in Europe by their ability to provide core perinatal health indicators.

Methods: The Euro-Peristat Network collected routine national data on a recommended set of core indicators from 2015 to 2021 using a federated protocol based on a common data model with 16 data items.

Description of Heterorhabditis americana n. sp. (Rhabditida, Heterorhabditidae), a new entomopathogenic nematode species isolated in North America.

Background: Heterorhabditis are important biological control agents in agriculture. Two Heterorhabditis populations, S8 and S10, were isolated from agricultural soils in the United States of America. Molecular analyses, based on mitochondrial and nuclear genes, showed that these populations are conspecific and represent a novel species of the "Bacteriophora" clade.